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30 items found for "Nina Babel"
- Dr. Josephine (Pina) Cardarelli - Dr. GPCR Podcast
Pina Cardarelli, CSO of GPCR Therapeutics.
- Label-free LC-MS based assay to characterize small molecule compound binding to cells
Here we developed and validated a label-free, liquid chromatography-mass spectrometry (LC-MS) based cell
- APEX2/AUR Biosensor: A Powerful Tool for Protein Interaction and Trafficking
Therefore, it’s a great molecular tool for proximity labeling approaches in living cells. During this process, APEX2 can label proteins in the vicinity, allowing the capture of a snapshot of After the labeling reaction, the researchers purified and biotinylated proteins (those that have been labeled by APEX2) and analyzed them using quantitative proteomics such as tandem mass tags.
- Fluorescent Ligands Targeting Intracellular Allosteric Binding Site of the Chemokine Receptor CCR2
August 2022 "Fluorescently labeled ligands are versatile molecular tools to study G protein-coupled receptors Starting from previously reported intracellular CCR2 antagonists, several tetramethylrhodamine (TAMRA)-labeled
- Identification of A2BAR as a potential target in colorectal cancer using novel fluorescent GPCR...
As well, fluorescent ligands were effective at monitoring real-time A2BAR receptor labeling using live-imaging modalities, and displayed high efficiency when used to label complex 3D cellular systems such as tumor
- C1-inhibitor influence on platelet activation by thrombin receptors agonists
Methods Platelets were isolated from healthy donor whole blood and then labeled with anti-CD62P and PAC1
- Conservation of Allosteric Ligand Binding Sites in G-Protein Coupled Receptors
These sites cluster at nine distinct locations, and each can be found in many different proteins.
- 📰 GPCR Weekly News, September 25 to October 1, 2023
Matthew Eddy and lab research on GPCR signaling mechanisms using NMR spectroscopy with labeled receptors extracellular chloride ion Illuminating GPCR signaling mechanisms by NMR spectroscopy with stable-isotope labeled
- 📰 GPCR Weekly News, May 13 to 19, 2024
via JAK1/STAT3 signal pathway A fluorescently-tagged tick kinin neuropeptide triggers peristalsis and labels Binders, Drugs, and more Silicon-Rhodamine Functionalized Evocalcet Probes Potently and Selectively Label
- GPCR/endocytosis/ERK signaling/S2R is involved in the regulation of the internalization...
We recently have shown that fluorescently labeled Hst1 (F-Hst1) targets and activates mitochondria, presenting
- 📰 GPCR Weekly News, May 15 to 21, 2023
and Signaling Monitoring the Reversibility of GPCR Signaling by Combining Photochromic Ligands with Label-free
- 📰 GPCR Weekly News, June 3 to June 9, 2024
7012 Crinetics Announces Positive Initial Findings at ENDO 2024 for Atumelnant in Two Ongoing, Open-Label
- 📰 GPCR Weekly News, November 6 to November 12, 2023
Diseases Sosei Heptares Operational Highlights and Consolidated Results for the Third Quarter and First Nine
- 📰 GPCR Weekly News, March 6 to 12, 2023
GPCR-targeting drugs: A renewed focus on a ubiquitous group of proteins arcoscreen will be at Bio-Europe 2023 in Basel
- Therapeutic validation of an orphan G protein‐coupled receptor
With the cloning revolution, several unidentified receptors have been found and were labelled as “orphan
- 📰 GPCR Weekly News, September 11 to 17, 2023
Niña Caculitan. GPCR Activation and Signaling Characterization of the real-time internalization of nine GPCRs reveals
- 📰 GPCR Weekly News, September 18 to 24, 2023
cancer Methods & Updates in GPCR Research Target immobilization on glass microfiber membranes as a label-free
- 📰 GPCR Weekly News, February 27 to March 5, 2023
Approach to Modern Drug Discovery Arcoscreen will present in the start-up village at Future Labs Live Basel
- 📰 GPCR Weekly News, January 1 to 7, 2024
Molecular Generation Models in Biological Properties Characterization of the real-time internalization of nine
- Unlocking the Future of Medicine: Advancements in GPCR Research
the Selective TACR2 Antagonist Tumonolide and its Aldehyde from a Marine Cyanobacterium Fluorophore-Labeled
- 📰 GPCR Weekly News, May 27 to June 2, 2024
Conference Crinetics Announces Positive Initial Findings At Endo 2024 For Atumelnant In Two Ongoing, Open-Label
- 📰 GPCR Weekly News, March 13 to 19, 2023
Monitoring the Reversibility of GPCR Signaling by Combining Photochromic Ligands with Label-free Impedance
- New role of β-arrestins in MOR signaling
According with the National Institute on Drug Abuse (NIDA) nearly 92, 000 Americans died from drug-involved
- 📰 GPCR Weekly News
Genetic Code Expansion To Enable Site-Specific Bioorthogonal Labeling of Functional G Protein-Coupled
- 📰 GPCR Weekly News, March 25 to March 31, 2024
This week's highlight includes congrats to: Junyi Liang, Niña Caculitan, and Adam W Smith for their research immobilization with enhanced fouling resistance, salt tolerance, and chromatographic performance Fluorine-19 labeling
- GPCR Updates: Celebrating Breakthroughs, New Course Launches Soon, and Exclusive Discounts! | Aug 26 - Sep 1, 2024
Updates in GPCR Research A nondestructive membrane engineering method using an amphiphilic polymer Labeling
- 📰 GPCR Weekly News, January 30 to February 5, 2023
Genetic code expansion to enable site-specific bioorthogonal labeling of functional G protein-coupled
- Adhesion GPCR Consortium Newsletter - May 2024
identifies extended synaptotagmin 1 as an intracellular interaction partner of GPR133 using proximity labeling