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January 2022 "After securing FDA approval for Wegovy last year, Novo Nordisk is strengthening its position

News Duke University Celebrates Nobel Prize Winner Robert Lefkowitz’s 50 Years of Scientific Discovery Novo Nordisk Foundation Grants Fuel Exciting GPCR and Signaling Protein Research Tools First-In-Class Drug

drugmaker Septerna amasses $288M in IPO Surrounded by AI bio giants, tiny startup Nabla Bio makes de novo

and Clinical Pharmacology 2026 GPCR Jobs Senior Associate Scientist - Global Research Technologies Novo Nordisk Scientist I - Global Research Technologies Novo Nordisk Postdoctoral Associate Research Technologist

Hey there, curious minds! Want to know what’s buzzing in the world of GPCRs? Join us for this week’s update, where you’ll find all the latest breakthroughs and exciting developments in GPCR research. We can’t wait to share it with you! This Week’s Highlights: Harnessing Deep Mutational Scanning for Enhanced Drug Discovery Cam Sinh Lu GPCR-BSD: a database of binding sites of human G-protein coupled receptors under diverse states Fan Liu , Han Zhou , Xiaonong Li , Liangliang Zhou , Chungong Yu , Haicang Zhang , Dongbo Bu 🤩 Seriously, why would you want to miss out on all the awesomeness that comes with a DrGPCR Premium Membership ? As a premium member , you have access to all the complimentary perks as well as: Dr. GPCR University 🎥 Access to the recorded classes of GPCR Courses and talks from Symposia 💲 Discounted GPCR courses GPCR Forum Initiate a vibrant conversation or seek assistance GPCR Events to keep you informed and engaged GPCR Jobs connecting candidates with positions Direct line to the Dr. GPCR community members Networking is crucial in professional endeavors :) Big Update! Starting in 2025, content access to Classified GPCR News will only be reserved for Premium Members. This strategic decision to limit free content is essential as we need to increase revenue to support the community. Classified GPCR News  Let’s dive into the   Classified GPCR News from November 4th to 10th, 2024 Industry News Lexaria Updates Fast-Moving GLP-1 'Arm's Race' Developments Five protein-design questions that still challenge AI Prix Galien USA: Domain Therapeutics Nominated for the Prestigious Best Startup Award Tectonic Therapeutic Announces Positive Phase 1a Results in AHA 2024 Presentation for TX45, a Long-acting, Fc-Relaxin Fusion Protein Nxera Pharma and Antiverse partner on GPCRs Nxera Pharma’s Partner Centessa Initiates Phase 2 Trial with ORX750, a Novel Orexin Receptor 2 (OX2R) Agonist AI, Synthetic Biology and Drug Discovery- with Aikium's Dr Venkatesh Mysore Trevena teeters in dangerous territory, terminating CEO and other execs amid strategic review Trevena Reports Third Quarter 2024 Results and Provides Business Update GPCR Events, Meetings, and Webinars NEW November 18 - 20, 2024 | 7th CB1 & CB2 Targeting Drug Development Summit November 25 - 26, 2024 | 6th International Conference on Stem Cell, Tissue Engineering and Regenerat November 25 - 27, 2024 | 1st Virtual GPCR Forum Conference November 26 - 28, 2024 | GPCRs-Targeted Drug Discovery Summit Europe December 10 - 12, 2024 | Pharmacology 2024 January 13 - 16, 2025 | PepTalk 2025 January 25 - 29, 2025 | SLAS 2025 February 15 - 16, 2025 | Structural and Functional Approaches in GPCR Drug Discovery February 15 - 19, 2025 | BPS 2025 February 16 - 21, 2025 | Harnessing the Power of Advanced Multimodal Approaches to GPCR Drug Discovery March 12 - 14, 2025 | NextGen Biomed 2025 March 25 - 28, 2025 | 10th German Pharm-Tox Summit April 1 - 5, 2025 | XXIII GEM Meeting in 2025 April 3 - 6, 2025 | ASPET 2025 April 14 - 17, 2025 | 20th Drug Discovery Chemistry April 24 - 27, 2025 | American Physiology Summit 2025 April 25 - 30, 2025 | AACR Annual Meeting 2025 May 12 - 15, 2025 | PEGS 2025 May 20 - 22, 2025 | SLAS Europe 2025 June 16 - 19, 2025 | BIO International Convention 2025 July 12 - 17, 2026 | 20th World Congress of Basic and Clinical Pharmacology GPCR Jobs Scientist I Cell Biology - Tectonic Therapeutic NEW Senior Principal Scientist, Medicinal Chemistry PhD fellowship in GPCR mechanosensing Senior Scientist, GPCR Pharmacology Research Associate - Professor Graeme Milligan Postdoc in Molecular Pharmacology - The Hauser Group Postdoctoral Scholar – iPSC in cardiac and endothelial cell function Protein Biochemist/Structural Biologist Senior Scientist/Staff Scientist, Computational Chemistry GPCR Activation and Signaling Pathophysiological significance and modulation of the transient receptor potential canonical 3 ion channel Smad transcription factors as mediators of 7 transmembrane G protein-coupled receptor signalling The voltage sensitivity of G-protein coupled receptors: Unraveling molecular mechanisms and physiological implications Sphingosine-1-phosphate activates LRRC8 volume-regulated anion channels through Gβγ signalling GPCR Binders, Drugs, and more PGE2 Binding Affinity of Hemocyte Membrane Preparations of Manduca sexta and Identification of the Receptor-Associated G Proteins in Two Lepidopteran Species GPCRs in Neuroscience Role of the GRK2/3 N-terminus in discriminating the endocytic effects of opioid agonist drugs GPCRs in Oncology and Immunology GPR56: GPCR as a guardian against ferroptosis Methods & Updates in GPCR Research Memprot.GPCR-ModSim: Modelling and simulation of membrane proteins in a nutshell Ciliary length variations impact cilia-mediated signaling and biological responses Structural and Molecular Insights into GPCR Function GPCR-BSD: a database of binding sites of human G-protein coupled receptors under diverse states Become a Premium Member! 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Biochemistry Post Doctoral Fellow Postdoc Position Senior Associate Scientist - Global Research Technologies Novo Nordisk Scientist I - Global Research Technologies Novo Nordisk Join Dr.

Pessac (Bordeaux) AI-Powered Drug Discovery and Antibody Innovation: DeciBio Q&A with Sean McClain, Founder

Hoist the sails, GPCR sailors! The GPCR ship is setting sail on a grand voyage across the vast ocean of research. Dive in and explore the depths in this week's GPCR update! This Week’s Highlights: SNX9 family mediates βarrestin-independent GPCR endocytosis Valeria Robleto , Ya Zhuo , Joseph Crecelius , Sara Benzow , Adriano Marchese Cannabinoid regulation of angiotensin II-induced calcium signaling in striatal neurons Rafael Rivas-Santisteban , Ana Muñoz , Jaume Lillo , Iu Raïch , Ana Rodríguez-Pérez , Gemma Navarro , José Labandeira-García , Rafael Franco Endomembrane GPCR signaling: 15 years on, the quest continues Davide Calebiro , Tamara Miljus , Shannon O'Brien Advances in the molecular understanding of GPCR-arrestin complexes Ivana Petrovic , Stephan Grzesiek , Polina Isaikina NMR spectroscopy reveals insights into mechanisms of GPCR signaling Larissa Silva , Anuradha Wijesekara , Matthew Eddy At Dr. GPCR, the journey is just beginning! We are dedicated to enhancing our community and delivering exceptional services to achieve our goal of leading a vibrant and healthy life , all thanks to the incredible potential of our beloved GPCRs. Join our fantastic tribe today by becoming a DrGPCR Premium Member ! Embrace the excitement of supporting us and unlocking incredible perks such as: Dr. GPCR University 🎥 Access to the recorded classes of GPCR Courses and talks from Symposia 💲 Discounted GPCR courses GPCR Forum Start an engaging discussion or request help in your research. GPCR Events You can start planning and save some dates in 2025 . GPCR Jobs Looking for a job or offering one? This is the place! Book a session with our Chief Match Maker. Direct line to the Dr. GPCR community members Build connections with other GPCR fans :) So much more to come! Big Update! 🚨 From 2025 onwards, only Premium Members will get the golden key to unlock the Classified GPCR News treasure trove. Why, you ask? We're working hard to keep the lights on and the coffee brewing by sprinkling a bit of magic on our revenue stream. It's all for the greater good! Classified GPCR News  Let’s dive into the   Classified GPCR News from November 11th to 17th, 2024 Industry News Centessa Launches Phase 2 Trial of ORX750 for Narcolepsy and IH Crinetics Pharmaceuticals Reports Third Quarter 2024 Financial Results and Provides Business Update Aelis Farma announces the positive results of its clinical Phase 1/2 Study with AEF0217 in young adults with Down syndrome Novartis pays Schrödinger $150M, bets billions on the back end to form drug discovery pact Aequorin: superior choice for GPCR calcium signalling GPCR: Structural Insights and Role in Drug Discovery Orion Biotechnology has a new website GPCR Events, Meetings, and Webinars November 25 - 26, 2024 | 6th International Conference on Stem Cell, Tissue Engineering and Regenerat ion November 25 - 27, 2024 | 1st Virtual GPCR Forum Conference November 26 - 28, 2024 | GPCRs-Targeted Drug Discovery Summit Europe December 10 - 12, 2024 | Pharmacology 2024 January 13 - 16, 2025 | PepTalk 2025 January 25 - 29, 2025 | SLAS 2025 February 15 - 16, 2025 | Structural and Functional Approaches in GPCR Drug Discovery February 15 - 19, 2025 | BPS 2025 February 16 - 21, 2025 | Harnessing the Power of Advanced Multimodal Approaches to GPCR Drug Discovery March 12 - 14, 2025 | NextGen Biomed 2025 March 25 - 28, 2025 | 10th German Pharm-Tox Summit April 1 - 5, 2025 | XXIII GEM Meeting in 2025 April 3 - 6, 2025 | ASPET 2025 April 14 - 17, 2025 | 20th Drug Discovery Chemistry April 24 - 27, 2025 | American Physiology Summit 2025 April 25 - 30, 2025 | AACR Annual Meeting 2025 May 12 - 15, 2025 | PEGS 2025 May 20 - 22, 2025 | SLAS Europe 2025 June 16 - 19, 2025 | BIO International Convention 2025 July 12 - 17, 2026 | 20th World Congress of Basic and Clinical Pharmacology GPCR Jobs Scientist I Cell Biology - Tectonic Therapeutic Senior Principal Scientist, Medicinal Chemistry PhD fellowship in GPCR mechanosensing Senior Scientist, GPCR Pharmacology Research Associate - Professor Graeme Milligan Postdoc in Molecular Pharmacology - The Hauser Group Postdoctoral Scholar – iPSC in cardiac and endothelial cell function Protein Biochemist/Structural Biologist Senior Scientist/Staff Scientist, Computational Chemistry GPCR Activation and Signaling SNX9 family mediates βarrestin-independent GPCR endocytosis A non-canonical mechanism of GPCR activation cGMP-dependent pathway and a GPCR kinase are required for photoresponse in the nematode Pristionchus pacificus Visualization of endogenous G proteins on endosomes and other organelles Mechanical stress and anionic lipids synergistically stabilize an atypical structure of the angiotensin II type 1 receptor (AT1) Identification and functional analysis of six melanocortin-4-receptor-like (MC4R-like) mutations in goldfish (Carassius auratus) Identification of a vital transcription factor of the alanine aminotransferase in the brown planthopper and its upstream regulatory pathways Divergent roles of DRY and NPxxY motifs in selective activation of downstream signalling by the apelin receptor GPR68 supports AML cells through the calcium/calcineurin pro-survival pathway and confers chemoresistance by mediating glucose metabolic symbiosis GPCR Binders, Drugs, and more Kinetic Basis for the Design of Azobenzene-Based Photoswitchable A2a Adenosine Receptor Ligands GPCRs in Cardiology, Endocrinology, and Taste Mechanistic Insights Into Redox Damage of the Podocyte in Hypertension Endurance exercise attenuates Gαq-RNAi induced hereditary obesity and skeletal muscle dysfunction via improving skeletal muscle Srl/MRCC-I pathway in Drosophila Chemogenetic activation of hepatic G12 signaling ameliorates hepatic steatosis and obesity GPCRs in Neuroscience GNG5 is a novel regulator of Aβ42 production in Alzheimer's disease Cannabinoid regulation of angiotensin II-induced calcium signaling in striatal neurons Receptor-dependent influence of R7 RGS proteins on neuronal GIRK channel signaling dynamics GPCRs in Oncology and Immunology Gallein, G protein βγ subunits inhibitor, suppresses the TGF-α-induced migration of hepatocellular carcinoma cells via inhibition of the c-Jun N-terminal kinase Methods & Updates in GPCR Research Conserved pattern-based classification of human odorant receptor multigene family Reviews, GPCRs, and more Endomembrane GPCR signaling: 15 years on, the quest continues Bound by the love for cholesterol: A transporter meets a GPCR Advances in the molecular understanding of GPCR-arrestin complexes Cholesterol sensing goes vegetarian Structural and Molecular Insights into GPCR Function NMR spectroscopy reveals insights into mechanisms of GPCR signaling Structural plasticity of arrestin-G protein coupled receptor complexes as a molecular determinant of signaling Become a Premium Member! 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Principal Scientist, In vitro pharmacology Senior Associate Scientist - Global Research Technologies Novo Nordisk Scientist I - Global Research Technologies Novo Nordisk Postdoctoral Associate Research Technologist

Principal Scientist, In vitro pharmacology Senior Associate Scientist - Global Research Technologies Novo Nordisk Scientist I - Global Research Technologies Novo Nordisk Postdoctoral Associate Research Technologist

Announces $103 Million Series A Financing Co-Led by MPM BioImpact and Novo Holdings Neurocrine Biosciences Principal Scientist, In vitro Pharmacology Senior Associate Scientist - Global Research Technologies Novo Nordisk Scientist I - Global Research Technologies Novo Nordisk Postdoctoral Associate Research Technologist

Biochemistry Post Doctoral Fellow Postdoc Position Senior Associate Scientist - Global Research Technologies Novo Nordisk Scientist I - Global Research Technologies Novo Nordisk Join Dr.

Principal Scientist, In vitro pharmacology Senior Associate Scientist - Global Research Technologies Novo Nordisk Scientist I - Global Research Technologies Novo Nordisk Postdoctoral Associate Research Technologist

Get your space suits on, GPCR cadets! The GPCR rocket is all fueled and ready to blast off into a galaxy of incredible advancements, now powered up with a series of cosmic GPCR events for the year ahead. It’s time to mark your calendars and save the dates—let’s make some stellar memories together! 🚀✨ This Week’s Highlights: Congrats to: Ya-Tzu Li , our notable contributor, for her superb undergrad paper along with Hao-Jen Hsu , Chun-Chun Chang , et al.   about State transitions of coupled Gi-protein: Insights into internal water channel dynamics within dopamine receptor D3 from in silico submolecular analyses Joseph Crecelius , Adriano Marchese , et al. for their excellent work on Receptor determinants for ß-arrestin functional specificity at C-X-C chemokine receptor 5 (CXCR5) Panjamaporn Sangwung , Alejandra Tomas , Kyle Sloop , et al. for their outstanding study on Class B1 GPCRs: insights into multireceptor pharmacology for the treatment of metabolic disease Milena Malcharek , Graham Ladds , et al. for their extensive research on The role of receptor activity-modifying proteins in obesity and diabetes mellitus Maleesha Ubhayarathna , Christopher Langmead , Gregory Stewart , et al. for their fantastic review on Molecular and structural insights into the 5-HT2C receptor as a therapeutic target for substance use disorders Leigh Walker , Christopher Langmead , Andrew Lawrence , et al. for their remarkable analysis on Targeting muscarinic receptors for the treatment of alcohol use disorders: Opportunities and hurdles for clinical development 👨‍💻 Why would you want to miss out on all the fun with a DrGPCR Premium Membership ? Being a premium member means you get to enjoy all the freebies plus: Access to the recorded classes of GPCR Courses . That's right, you're about to level up your knowledge game! Discounted GPCR courses - because who doesn't love a good deal?  Exclusive access to private groups  Over 30 recorded talks from Symposia - that's a lot of brain food!  Job listings for candidates and positions to connect! Exciting event listings to keep you on your toes  Direct line to all the cool cats in the GPCR community - Networking is key, right?  Big Update! From 2025, only Premium Members will have access to Classified GPCR News. This transition will enable us to invest in higher-quality content and resources, ensuring our community gets the very best insights and updates! Classified GPCR News  Let’s dive into the   Classified GPCR News from October 28th to November 3rd, 2024 Industry News Nxera Pharma Operational Highlights and Consolidated Results for the Third Quarter and First Nine Months of 2024 Nasdaq debutante Septerna swells its IPO to $331m Nxera Pharma and Antiverse Enter Collaboration To Design Novel GPCR- Targeted Antibody Therapeutics Using Generative AI Zombie Fungi Hijack Hosts’ Brains GPCR Therapeutics, Inc. has received Orphan Drug Designation (ODD) from the FDA for its hematopoietic stem cell mobilization agent It’s not just obesity. Drugs like Ozempic will change the world GPCR Events, Meetings, and Webinars November 5 - 7, 2024 | 16th Annual PEGS Europe   NEW November 25 - 26, 2024 | 6th International Conference on Stem Cell, Tissue Engineering and Regenerat November 25 - 27, 2024 | 1st Virtual GPCR Forum Conference November 26 - 28, 2024 | GPCRs-Targeted Drug Discovery Summit Europe NEW December 10 - 12, 2024 | Pharmacology 2024 NEW January 13 - 16, 2025 | PepTalk 2025 NEW January 25 - 29, 2025 | SLAS 2025 NEW February 15 - 16, 2025 | Structural and Functional Approaches in GPCR Drug Discovery NEW February 15 - 19, 2025 | BPS 2025 NEW February 16 - 21, 2025 | Harnessing the Power of Advanced Multimodal Approaches to GPCR Drug Discovery NEW March 12 - 14, 2025 | NextGen Biomed 2025 NEW March 25 - 28, 2025 | 10th German Pharm-Tox Summit NEW April 1 - 5, 2025 | XXIII GEM Meeting in 2025 NEW April 3 - 6, 2025 | ASPET 2025 NEW   April 14 - 17, 2025 | 20th Drug Discovery Chemistry NEW   April 24 - 27, 2025 | American Physiology Summit 2025 NEW April 25 - 30, 2025 | AACR Annual Meeting 2025 NEW May 12 - 15, 2025 | PEGS 2025 NEW May 20 - 22, 2025 | SLAS Europe 2025 NEW June 16 - 19, 2025 | BIO International Convention 2025 July 12 - 17, 2026 | 20th World Congress of Basic and Clinical Pharmacology GPCR Jobs Scientist I Cell Biology - Tectonic Therapeutic PhD fellowship in GPCR mechanosensing Senior Scientist, GPCR Pharmacology Research Associate - Professor Graeme Milligan Postdoc in Molecular Pharmacology - The Hauser Group Postdoctoral Scholar – iPSC in cardiac and endothelial cell function Protein Biochemist/Structural Biologist Senior Scientist/Staff Scientist, Computational Chemistry GPCR Activation and Signaling GPCR signalling: Yet another variant route in a highly complex road map Transactivation of the EGF receptor as a novel desensitization mechanism for G protein-coupled receptors, illustrated by dopamine D2-like and β2 adrenergic receptors Receptor determinants for ß-arrestin functional specificity at C-X-C chemokine receptor 5 (CXCR5) State transitions of coupled Gi-protein: Insights into internal water channel dynamics within dopamine receptor D3 from in silico submolecular analyses GPCRs in Cardiology, Endocrinology, and Taste Adipose tissue in older individuals: a contributing factor to sarcopenia Asprosin regulates male reproduction in teleosts: an in vitro study in Channa punctata GPCRs in Neuroscience Neuron specific quantitation of Gαolf expression and signaling in murine brain tissue Regulator of G protein signaling 6 (RGS6) in dopamine neurons promotes EtOH seeking, behavioral reward, and susceptibility to relapse GPCRs in Oncology and Immunology The GPCR adaptor protein Norbin controls the trafficking of C5aR1 and CXCR4 in mouse neutrophils Mechanistic exploration of bioactive constituents in Gnetum gnemon for GPCR-related cancer treatment through network pharmacology and molecular docking The Effect of Cancer-Associated Mutations on Ligand Binding and Receptor Function - A Case for the 5-HT2C Receptor Reviews, GPCRs, and more Functional consequences of spatial, temporal and ligand bias of G protein-coupled receptors Ligand bias at the muscarinic acetylcholine receptor family: Opportunities and challenges Class B1 GPCRs: insights into multireceptor pharmacology for the treatment of metabolic disease The role of receptor activity-modifying proteins in obesity and diabetes mellitus Molecular and structural insights into the 5-HT2C receptor as a therapeutic target for substance use disorders Targeting muscarinic receptors for the treatment of alcohol use disorders: Opportunities and hurdles for clinical development Chemokine CXCL13-CXCR5 signaling in neuroinflammation and pathogenesis of chronic pain and neurological diseases Structural and Molecular Insights into GPCR Function Native mass spectrometry prescreening of G protein-coupled receptor complexes for cryo-EM structure determination Molecular Basis of MC1R Activation: Mutation-Induced Alterations in Structural Dynamics Molecular determinants of neuropeptide-mediated activation mechanisms in tachykinin NK1 and NK2 receptors Become a Premium Member! 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Good day readers! This week we’ve curated 20 GPCR papers, 3 new events, 9 industry news, and 3 job opportunities! Discover our comprehensive coverage of GPCRs, We welcome GPCR paper suggestions! Submit your publications to Hello@DrGPCR.com for consideration. This week's highlight: Dr. Matthew T Eddy and his team's research on A2A adenosine receptor activation by G protein and mutations. Are you looking to hire? Or maybe looking for your next opportunity? Our Chief Matchmaker, Mark Schmeizl, is here to assist you. Simply complete this form to get in touch with him. November Dr. GPCR Newsletter is out now. Subscribe for this month's video featuring Dr. Alix Rouault. Ensure to catch the upcoming episodes of Dr. GPCR Podcast featuring Dr. Neil Grimsey and Dr. Katarzyna Marcinkiewicz. Be sure to look at the Classified GPCR News from November 27th to December 3rd, 2023. GPCR Activation and Signaling DANGER Signals Activate G -Protein Receptor Kinases Suppressing Neutrophil Function and Predisposing to Infection After Tissue Trauma Single-molecule visualization of human A2A adenosine receptor activation by a G protein and constitutively activating mutations Distinct activation mechanisms of β-arrestin-1 revealed by 19F NMR spectroscopy Role of protease activated receptor 4 (PAR4) in mouse models of acute and chronic kidney injury GPCR Binders, Drugs, and more High-throughput virtual screening of potential inhibitors of GPR52 using docking and biased sampling method for Huntington's disease therapy Rational design of highly stabilized and selective adrenomedullin analogs Novel multi-target ligands of dopamine and serotonin receptors for the treatment of schizophrenia based on indazole and piperazine scaffolds-synthesis, biological activity, and structural evaluation Flavonoids as G Protein-coupled Receptors Ligands: New Potential Therapeutic Natural Drugs GPCRs in Cardiology, Endocrinology, and Taste Phenylacetyl glutamine (PAGln) enhances cardiomyocyte death after myocardial infarction through β1 adrenergic receptor Comparative transcriptomic analysis of mammary gland tissues reveals the critical role of GPR110 in palmitic acid-stimulated milk protein and fat synthesis GPCRs in Neuroscience Targeting sensory neuron GPCRs for peripheral neuropathic pain GPCRs in Oncology and Immunology Expression prevalence and dynamics of GPCR somatostatin receptors 2 and 3 as cancer biomarkers beyond NET: a paired immunohistochemistry approach The combination of brentuximab vedotin and chidamide synergistically suppresses the proliferation of T-cell lymphoma cells through the enhancement of apoptosis Methods & Updates in GPCR Research Modulating signalling lifetime to optimise a prototypical animal opsin for optogenetic applications Imaging flow cytometry of tumoroids: A new method for studying GPCR expression GPCR molecular dynamics forecasting using recurrent neural networks A method for multiple-sequence-alignment-free protein structure prediction using a protein language model Reviews, GPCRs, and more Potential of olfactory neuroepithelial cells as a model to study schizophrenia: A focus on GPCRs (Review) Structural and Molecular Insights into GPCR Function Fully activated structure of the sterol-bound Smoothened GPCR-Gi protein complex Deep Learning Dynamic Allostery of G-Protein-Coupled Receptors Industry News Sosei Heptares to take back GPCR agonist after GSK changes course All-rounder among receptors inspires drug research Tectonic Therapeutic Announces Start of First Clinical Program for GPCR-Targeted Biologic Trevena Announces Acceptance of Abstract Examining the Use of OLINVYK in Patients with Acute Burn Injuries Carmot Therapeutics Enters into Definitive Merger Agreement with Roche New Clinical Trial Explores Novel Target In Parkinson’s Treatment GPCR Events, Meetings, and Webinars January 16 - 19, 2024 | 23rd Annual PEP Talk February 3 - 7, 2024 | SLAS2024 International Conference and Exhibition February 11 - 14, 2023 | 2024 BPS Annual Meeting March 5 - 7, 2024 | 3rd GPCRs - Targeted Drug Discovery Summit March 23 - 24, 2024 | Ligand Recognition and Molecular Gating Seminar March 24 - 29, 2024 | Ligand Recognition and Molecular Gating Conference April 1 - 4, 2024 | 19th Annual Drug Discovery Chemistry April 4 - 7, 2024 | American Physiology Summit April 5 - 10, 2024 | AACR Annual Meeting April 22 - 23, 2024 | Endocrine Metabolic GPCRs May 13 - 17, 2024 | 20th Annual PEGS Boston Summit May 16 - 19, 2024 | ASPET 2024 May 27 - 29, 2024 | SLAS Europe 2024 Conference and Exhibition June 2 - 7, 2024 | Chemotactic Cytokines NEW June 9 - 14, 2024 | 2024 Phosphorylation and G-Protein Mediated Signaling Networks NEW June 25 - 29, 2024 | FENS Forum 2024 October 2 - 4, 2024 | 9th GPCRs in Medicinal Chemistry NEW October 23 - 25, 2024 | 11th Adhesion GPCR Workshop July 12 - 17, 2026 | 20th World Congress of Basic and Clinical Pharmacology 2026 GPCR Jobs NEW Principal scientist – oncology biomarker expert NEW Postdoctoral Fellow NEW Scientific Assistant Scientist Lead Researcher Post-Doctoral Fellow Sr Scientist in Obesity, Muscle, and Metabolism Post-Doctoral Fellow Explore Dr. GPCR Ecosystem

July 2022 "I’m happy to share that I’m starting a new position as Scientific co-founder LASEREDD Therapeutics

Subject in TRV045 Proof-of-Concept Trial Evaluating S1PR Mechanism of Action and Target Engagement Novo Nordisk's GLP-1 for Type II diabetes approved for first-line treatment The Lundbeck Foundation is awarding

University’s first female Professor of Chemistry, former president of the Royal Society of Chemistry and Founder highly prestigious international award – exemplified by the fact that other winners this year are the co-founders

Submit a logo design by Nov 1st on the Logo Contest page. relatedness Industry News Nobel Laureates Highlight Symposium Celebrating Lefkowitz’s 50 Years at Duke Novo Nordisk stops Ozempic kidney trial after early signs of success Sosei and PharmEnable extend neurological

Immunotherapy Drug HTL0039732 Exscientia Business Update for Second Quarter and First Half of 2023 Novo Nordisk to acquire Inversago Pharma to develop new therapies for people living with obesity, diabetes

Health (RHU) SPRINT consortium grant to progress its proprietary CCR8 antibody candidate to the clinic Novo Radioligand Therapy Production Plant Novartis’ Lutathera reduces disease progression risk in GEP-NET trial Novo Nordisk hits $500 billion in market value as it flags soaring demand for Wegovy, Ozempic Dr.

December 2021 OMass Therapeutics's founder, Carol Robinson, has been awarded the prestigious Louis-Jeantet Prize for Medicine 2022 by the Louis-Jeantet Foundation and the 2022 Benjamin Franklin Medal in Chemistry from The Franklin Institute "Huge congratulations to our founder, Carol Robinson, who has been awarded the prestigious Louis-Jeantet Prize for Medicine 2022 by the Louis-Jeantet Foundation and the 2022 Benjamin

Submit your logo design by Nov 1st on the Logo Contest page. Company in Immuno-Oncology, Domain Therapeutics, Presents Groundbreaking Advancements at ESMO 2023 Novo Nordisk to Buy Hypertension Treatment from KBP Biosciences Exscientia to Present New Preclinical Data

and Provides Business Update Crinetics Pharmaceuticals: Paltusotine Phase 3 Data Presented At ENDO Novo Nordisk to Acquire Inversago Pharma GPCR Events, Meetings, and Webinars NEW Antiverse: Reimagining Therapeutic

Michel Bouvier, J Silvio Gutkind, and team found that Gαs is essential for GRK selectivity and gene regulation Channel Drug Developer Maxion Therapeutics Appoints Eva-Lotta Allan as Chair of its Board of Directors Novo Nordisk and Evotec collaborate to launch LAB eN², a translational drug discovery accelerator, to address

enable the identification of selective antagonists Industry News Inside the FDA's Form 483 findings at Novo Nordisk's North Carolina semaglutide plant Excellerate Bioscience Announces Site Relocation AI can help

Raised To Discover And Advance Novel Oral Small Molecule Medicines Targeting G Protein-Coupled Receptors Novo Nordisk A/S: Semaglutide 2.4 mg reduces the risk of major adverse cardiovascular events by 20% in adults

Indeed, incretin-based drugs like Novo Nordisk's Wegovy and Eli Lilly's Zepbound are advancing diabetes