GPCR Podcast << Back to podcast list Dr. Nicola J. Smith About Dr. Nicola J. Smith Dr. Nicola J Smith is an expert in molecular pharmacology with a track record in exploring GPCR structure-function Smith’s team has made advances in the understanding of how an orphan GPCR exerts its effects both in from other receptors) for orphan GPCRs, named GPCR-CoINPocket. Her career goal is to leverage this expertise to establish a research program that takes orphan GPCRs

GPCR Podcast << Back to podcast list Brendan Wilkins About Brendan Wilkins "Brendan completed his undergraduate G protein-coupled receptor (GPCR), GPR37L1. Brendan’s PhD project focuses on the orphan GPCR GPR146. GPCRs. GPCR Thanks for listening to this podcast episode This short survey will help us understand your needs

< GPCR News < GPCRs in Oncology and Immunology Activation of orphan receptor GPR132 induces cell differentiation Here, we showed that genetic activation of the orphan GPCR GPR132 significantly induced cell differentiation In summary, this study demonstrated that activation of orphan GPR132 represents a potential strategy GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs, and more Methods & Updates in GPCR Research GPCRs in Neuroscience GPCRs in Cardiology, Endocrinology, and Taste GPCRs

< GPCR News < GPCRs in Oncology and Immunology Orphan receptor GPR50 attenuates inflammation and insulin GPR50 (G protein-coupled receptor 50) is an orphan GPCR that shares the highest sequence homology with Source Contribute to the GPCR News Coming soon Become a Contributor Classified GPCR News Call for GPCR papers GPCR Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs, and more Methods & Updates in GPCR Research GPCRs in Neuroscience GPCRs in Cardiology

December 6, 2024 Abstract "GPR87 is a G protein-coupled seven-transmembrane receptor first described as an orphan receptor, these data are preliminary and inconsistent, and IUPHAR is currently considering GPR87 as an orphan Authors Katrin Sak Tags Carcinogenesis , GPR87 , LPA receptor , Metastasis , Orphan GPCR , P2Y receptor GPCR News GPCR Jobs Call for GPCR papers GPCR Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs, and more Methods & Updates in GPCR Research GPCRs

< GPCR News < GPCRs in Oncology and Immunology The orphan G protein-coupled receptor 141 expressed in Here, we demonstrate that GPR141, an orphan GPCR belonging to the class A receptor family, suppresses Source Contribute to the GPCR News Coming soon Become a Contributor Classified GPCR News Call for GPCR papers GPCR Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs, and more Methods & Updates in GPCR Research GPCRs in Neuroscience GPCRs in Cardiology

< GPCR News < GPCRs in Oncology and Immunology High expression of GPR50 promotes the proliferation, migration GPR50 is an orphan GPCR. News Coming soon Become a Contributor Classified GPCR News Call for GPCR papers GPCR Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs, and more Methods & Updates in GPCR Research GPCRs in Neuroscience GPCRs in Cardiology, Endocrinology, and Taste GPCRs

GPCR Podcast << Back to podcast list Dr. Simone Prömel & Dr. Ines Liebscher About Dr. of the Adhesion GPCR Latrophilin-1. GPCR Ecosystem About Dr. Ines Liebscher Dr. During her medical studies in Leipzig, she had her first encounter with an orphan GPCR as the subject Her postdoctoral work leads her to investigate a whole family of orphan receptors: adhesion GPCRs.

< GPCR News < GPCRs in Oncology and Immunology Structural Basis for the Recognition of GPRC5D by Talquetamab G-protein-coupled receptor class C group 5 member D (GPRC5D), an orphan GPCR predominantly expressed Classified GPCR News Call for GPCR papers GPCR Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs, and more Methods & Updates in GPCR Research GPCRs GPCR News and get weekly notifications about the GPCR field Share < Previous Next >

< GPCR News < GPCRs in Oncology and Immunology GPR176 promotes fibroblast-to-myofibroblast transition Miyashima, Hironobu Ishimaru, Kazuhito Tsuboi Tags Fibroblast , Fibrosis , Gpr176 , Myofibroblast , Orphan GPCR , TGFβ1 Source Contribute to the GPCR News Coming soon Become a Contributor Classified GPCR News Call for GPCR papers GPCR Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs, and more Methods & Updates in GPCR Research GPCRs in Neuroscience

Retreat 2023 About Program Registration Logo Contest Committee Sponsors GPCR Retreat Program < Back to Thursday, November 2nd / 1:45 PM - 2:45 PM Title: Virion Display to Discover a Novel Ligand of the Orphan My interests in research are primarily directed towards methods that study GPCRs and GPCR signaling, GPCR Previous Event Next Event Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires 22nd GPCR Retreat Sponsored by

GPCR Podcast << Back to podcast list Dr. Nariman Balenga About Dr. I followed my interest in allergy and GPCRs by joining the lab of Dr. I was fascinated by the multitude of processes that are regulated/dysregulated by GPCRs and RGS proteins A fungal serine protease allergen with GPCR-modulating features was discovered as a new biomarker and I studied the function of RGS5, calcium-sensing receptor, and an orphan adhesion GPCR, GPR64/ADGRG2 in

GPCR Podcast << Back to podcast list Dr. Brian Bender About Dr. Brian Bender Dr. Brain’s work there primarily focused on structure prediction of GPCRs from sparse experimental data. screen large compound libraries with the goal of finding new chemical matter to probe understudied and orphan Brian is one of the organizers of the upcoming Transatlantic ECI GPCR Symposium . Dr. GPCR Ecosystem Thanks for listening to this podcast episode This short survey will help us understand

GPCR Podcast << Back to podcast list Dr. Hannes Schihada About Dr. My project involved the development of FRET/BRET -based GPCR conformational biosensors, which can be a Marie Sklodowska Curie PostDoc Fellowship in order to investigate and find better ligands for the orphan class A GPCRs , GPR3 , GPR6 , and GPR12 . GPCR Ecosystem Thanks for listening to this podcast episode This short survey will help us understand

< GPCR News < GPCRs in Oncology and Immunology The binding mechanism of an anti-multiple myeloma antibody to the human GPRC5D homodimer Published date June 19, 2024 Abstract "GPRC5D is an atypical Class C orphan News Coming soon Become a Contributor Classified GPCR News Call for GPCR papers GPCR Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs, and more Methods & Updates in GPCR Research GPCRs in Neuroscience GPCRs in Cardiology, Endocrinology, and Taste GPCRs

Full Agenda Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Download PDF Program Our first main research aspect is the identification of endogenous ligand of GPCRs. Our third main research aspect is working mechanism of GPCR. We also identified that orphan receptor GPR64 forms complex with β-arrestin-1 and CFTR at apical membrane (Cell 2021, 2023, Nature 2023b), bile acids or its derivatives by GPCRs (Nature 2020)."

< GPCR News < GPCRs in Oncology and Immunology Dynamic Phosphoproteomics of BRS3 Activation Reveals the for Cell Migration Published date June 25, 2023 Abstract "Bombesin receptor subtype-3 (BRS3) is an orphan News Coming soon Become a Contributor Classified GPCR News Call for GPCR papers GPCR Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs, and more Methods & Updates in GPCR Research GPCRs in Neuroscience GPCRs in Cardiology, Endocrinology, and Taste GPCRs

GPCR Podcast << Back to podcast list Dr. Alexander S. Hauser About Dr. Alexander S. methods to identify human signaling systems and thereby discovered endogenous peptides activating several orphan Award” for his work on GPCRs. Dr. Alexander S. GPCR Ecosystem Thanks for listening to this podcast episode This short survey will help us understand

GPCR Podcast << Back to podcast list Dr. Ralf Jockers About Dr. His laboratory was among the first to demonstrate the oligomerization of GPCRs. He established the concept of ligand-independent functions of orphan receptors in heterodimers with other GPCRs. His lab was among the first to discover mitochondrial functions of GPCRs.

GPCR Podcast << Back to podcast list Dr. Françoise Bachelerie About Dr. Paris-Saclay University with expertise in immunology and virology related to Host/Virus interactions and GPCR FB’ team has identified the orphan CXCR7/ACKR3 receptor as being the 2nd receptor for CXCL12, which behaves nomenclature for chemokine receptors that are categorized into a large subgroup of G protein–coupled (GPCR GPCR Thanks for listening to this podcast episode This short survey will help us understand your needs

GPCR Podcast << Back to podcast list Dr. David E. Computational Receptor Biology at the University of Copenhagen where he leads a research cluster for GPCR He later identified physiological hormones of such under characterized ‘orphan’ receptors and functional Join me a learn more about David’s work, his career trajectory, and GPCRdb. Dr. David E. GPCR Ecosystem Thanks for listening to this podcast episode This short survey will help us understand

< GPCR News < GPCRs in Oncology and Immunology GPR37 expression as a prognostic marker in gliomas: a GPR37 is an orphan G protein-coupled receptor (GPCR) that is implicated in different physiological pathways News Coming soon Become a Contributor Classified GPCR News Call for GPCR papers GPCR Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs, and more Methods & Updates in GPCR Research GPCRs in Neuroscience GPCRs in Cardiology, Endocrinology, and Taste GPCRs

GPCR Podcast << Back to podcast list Dr. Antony A. Boucard Jr About Dr. Antony A. Boucard Jr. Dr. It is then that his interest bloomed for the study of GPCRs while joining the group of Dr. In this institution dear to the heart of GPCR enthusiasts given that its faculty personnel included Dr After a relocation to Stanford University where he pioneered work on ligand discovery for then orphan adhesion GPCRs, Dr.

< GPCR News < GPCRs in Oncology and Immunology [Inhibitory effect of downregulating G protein-coupled Classified GPCR News Call for GPCR papers GPCR Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs, and more Methods & Updates in GPCR Research GPCRs and molecular insights into GPCR function GPCR Activation and Signaling More from Dr. GPCR News and get weekly notifications about the GPCR field Share < Previous Next >

< GPCR News < GPCRs in Oncology and Immunology GprC of the nematode-trapping fungus Arthrobotrys flagrans News Coming soon Become a Contributor Classified GPCR News Call for GPCR papers GPCR Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs, and more Methods & Updates in GPCR Research GPCRs in Neuroscience GPCRs in Cardiology, Endocrinology, and Taste GPCRs GPCR News and get weekly notifications about the GPCR field Share < Previous Next >

Full Agenda Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Download PDF Program map of thermogenic fat Vasiliki Karagiannakou GAIN Domain Dynamics And Its Relevance For Adhesion GPCR This made me pursue my higher education in the field of adhesion GPCRs. Emmanouil Kyrloglou on the web Adhesion GPCR Consortium LinkedIn A single cell GPCR map of thermogenic , located within the GPCR autoproteolysis inducing (GAIN) domain.

Full Agenda Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Download PDF Program GPCR Community Presentation Breaking Barriers: My Journey from Mexico to the Heart of the Dr. GPCR Ecosystem and beyond About Monserrat Avila Zozaya "My doctoral research was focused on investigating My research focuses on understanding the molecular mechanisms of adhesion GPCRs (aGPCRs) in lymphatic GPCR < Previous Session Next Session >

Full Agenda Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Download PDF Program function The NTF Release Sensor Approach for Drug Discovery for Human Adhesion GPCRs Stephanie Häfner bioSens-All: A Multiparametric BRET-Based Platform for Comprehensive Profiling of adhesion GPCR Signaling Stephanie Häfner Abstract "G Protein-coupled receptors (GPCRs) are common drug targets, yet no approved ), with a particular focus on the adhesion GPCRs (aGPCRs) family.