Hello everyone! Check out our latest coverage of GPCRs this week, featuring 15 insightful research papers and industry updates. Stay informed with the latest GPCR research and industry news. This week's highlight includes congrats to: Cam Sinh Lu, for his first Dr. GPCR contributor article Extracellular signal-regulated kinases – a potential pathway for GPCR-targeted drug discovery Nicola J Smith, Lauren T May, and Natasha L Grimsey for their work on Highlights and hot topics in GPCR research from 'Down Under' Dr. GPCR University Today marks the final day of the Dr. GPCR University workshop on Advanced Data Analysis for GPCR Pharmacology, led by the esteemed Dr. Sam Hoare. It's been a remarkable experience with participants joining us from around the globe. We're thrilled to announce that Dr. Terry Kenakin will return for two consecutive courses in September and October 2024. Stay tuned for more details, and be ready to register in July 2024. Dr. GPCR Podcast We have thrilling news—Episode 153 of the Dr. GPCR Podcast featuring Dr. Jacek Mokrosiński is live! Titled "Embracing Networking for Professional Growth" Our podcast episodes are now available in video format on our website. Revisit your favorite episodes and catch up on any you’ve missed. Tune in and enjoy the visual experience! Dr. GPCR Matchmaking Read Mark's job spotlight article for a Principal Scientist in In Vitro Pharmacology! Mark recently discussed this exciting opportunity with Beth Fleck, Director of In Vitro Pharmacology at Crinetics Pharmaceuticals! GPCR Event Highlight We are delighted to announce our first in-person event in collaboration with the Adhesion GPCR Consortium: The 11th Adhesion GPCR Workshop will be held in vibrant Mexico City from October 23 to 25, 2024. Join the global GPCR community and share your research—submit your abstract using this form. We are also seeking sponsors to support this exciting event that unites scientists worldwide to explore all aspects of adhesion GPCR biology. Interested in sponsoring? Please email us at Hello@DrGPCR.com. Let’s dive into the Classified GPCR News from May 20th to 26th, 2024. Adhesion GPCRs Adhesion G Protein-Coupled Receptor Gpr126 (Adgrg6) Expression Profiling in Diseased Mouse, Rat, and Human Kidneys GPCR Activation and Signaling Differential regulation of G protein-coupled receptor-associated proteins in the caudate and the putamen of cynomolgus macaques following chronic ethanol drinking GRK5 is required for adipocyte differentiation through ERK activation GPCR Binders, Drugs, and more Flipping the GPCR Switch: Structure-Based Development of Selective Cannabinoid Receptor 2 Inverse Agonists Development of Putative Bivalent Dicovalent Ligands for the Adenosine A1 Receptor GPCRs in Cardiology, Endocrinology, and Taste Sodium/Potassium ATPase Alpha 1 Subunit Fine-tunes Platelet GPCR Signaling Function and is Essential for Thrombosis GPCRs in Oncology and Immunology Enterococcus-derived tyramine hijacks α2A-adrenergic receptor in intestinal stem cells to exacerbate colitis The EBI2 receptor is coexpressed with CCR5 in CD4+ T cells and boosts HIV-1 R5 replication Methods & Updates in GPCR Research Evaluation and comparison of colorimetric outputs for yeast-based biosensors in laboratory and point-of-use settings Quantitative proteomics reveals CLR interactome in primary human cells Exploiting Cell-Based Assays to Accelerate Drug Development for G Protein-Coupled Receptors TOR signaling regulates GPCR levels on the plasma membrane and suppresses the Saccharomyces cerevisiae mating pathway Reviews, GPCRs, and more Highlights and hot topics in GPCR research from 'Down Under' Apelin receptor dimer: Classification, future prospects, and pathophysiological perspectives Structural and Molecular Insights into GPCR Function Bilayer lipids modulate ligand binding to atypical chemokine receptor 3 Industry News New cannabinoid CB1 receptor antagonists disclosed in Inversago patent Orion Biotechnology will be attending BIO 2024 Antiverse is attending BIO 2024 Septerna to Present Preclinical Data from GPCR Drug Discovery Engine at ENDO 2024 The Promise of Oxytocin: Novel Approaches for Targeting Oxytocin Receptors in Autism Spectrum Disorder and Psychiatric Disorders GPCR Events, Meetings, and Webinars NEW June 1 - 4, 2024 | ENDO 2024 NEW June 3 - 6, 2024 | BIO 2024 June 2 - 7, 2024 | Chemotactic Cytokines June 4, 2024 | Live Webinar ‘It All Starts With a Protein – Protein Sciences as a Key to Success in Drug Discovery’ June 9 - 14, 2024 | 2024 Phosphorylation and G-Protein Mediated Signaling Networks June 25 - 29, 2024 | FENS Forum 2024 October 2024 | Biologics US 2024 October 2 - 4, 2024 | 9th GPCRs in Medicinal Chemistry October 23 - 25, 2024 | 11th Adhesion GPCR Workshop July 12 - 17, 2026 | 20th World Congress of Basic and Clinical Pharmacology 2026 GPCR Jobs HIGHLIGHT Principal Scientist, In vitro pharmacology NEW Senior Scientist - Receptor Pharmacology NEW PostDoctoral Scientist Senior Research Associate/Associate Scientist, Protein Science Post-Doctoral Fellow—Pharmacology/Cell Biology/Biochemistry Post Doctoral Fellow Postdoc Position Senior Associate Scientist - Global Research Technologies Novo Nordisk Scientist I - Global Research Technologies Novo Nordisk Join Dr. GPCR Ecosystem

September 2022 Regulator of G Protein Signaling 20 Correlates with Long Intergenic Non-Coding RNA (lincRNAs

Remember to check out the weekly Classified GPCR News from August 14 to 20, 2023 Adhesion GPCRs Amelioration November 2 - 4, 2023) MPGPCR Conference (November 15 -17, 2023) ASCEPT Annual Scientific Meeting (November 20

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Dr. GPCR Podcast << Back to podcast list Dr. Jennifer Pluznick About this episode Dr. Pluznick discovered that olfactory receptors in mice are also expressed in their kidneys and blood vessels. Her research is focused on the role of chemosensory GPCRs in regulating renal and cardiovascular function, and identifying renal/cardiovascular olfactory receptor ligands, and relating them to whole-animal physiology. This work contributes to a better understanding of how the kidney helps maintain homeostasis in humans. Jennifer is currently an assistant professor of physiology at the Johns Hopkins School of Medicine. She received her undergraduate degree in biology from Truman State University and earned her Ph.D. in renal physiology from the University of Nebraska Medical Center. She then spent five years training as a postdoctoral fellow in the laboratory of Michael Caplan at Yale University, where she studied both renal physiology and sensory biology systems and focused on olfaction. Dr. Jennifer Pluznick on the web John Hopkins Pluznick Lab Pubmed Ted Talk Dr. GPCR Ecosystem Thanks for listening to this podcast episode This short survey will help us understand your needs to bring you exciting and informative content; this short survey should take 5 minutes to fill. Listen and subscribe to where you get your podcasts. << Previous Podcast Episode Next Podcast Episode >>

Even though Maria stumbled upon the GPCR field, her 20 years in both academia and in the industry working