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6 items found for "PLCβ"
- G Protein-coupled Receptor-mediated Membrane Targeting of PLCγ2 is Essential for Neutrophil Chemotaxis
current dogma is that chemoattractants G protein-coupled receptors (GPCRs) activate β phospholipase C (PLCβ ) while receptor tyrosine kinases (RTKs) activate γ phospholipase C (PLCγ). chemoattractant/GPCR-mediated membrane recruitment of PLCγ2 constitutes GPCR-mediated phospholipase C (PLC receptor (GPCR) , calcium-promoted Ras inactivator (CAPRI) , chemotaxis , neutrophils , phospholipase C (PLC
- Ascitic Shear Stress Activates GPCRs and Downregulates Mucin 15 to Promote OvarianCancer Malignancy
Katherine Maturen, Analisa DiFeo, David Nordsletten Tags G-protein coupled receptors (GPCR) , NF-κB , PLCβ
- Stimulation of ectopically expressed muscarinic receptors induces IFN-γ but suppresses IL-2 production by inhibiting activation of pAKT pathways in primary T cells
G-protein-coupled muscarinic receptors (M1 and synthetic hM3Dq) can activate primary mouse T cells if PLCβ1 Resting peripheral hM3Dq+PLCβ1 (hM3Dq/β1) T cells did not respond to clozapine, an hM3Dq agonist, unless they were preactivated by TCR and CD28 stimulation which increased hM3Dq and PLCβ1 expression.
- Gi/o GPCRs drive the formation of actin-rich tunneling nanotubes in cancer cells via a Gβγ/PKCα/FARP1/Cdc42 axis
Subsequent signaling analysis reveals a strict requirement of phospholipase C β3 (PLCβ3) and its downstream
- Coronavirus Porcine Epidemic Diarrhea Virus Utilizes Chemokine Interleukin-8 to Facilitate Viral Replication by Regulating Ca2+ Flux
Finally, we identified that G protein-coupled receptor (GPCR)-phospholipase C (PLC)-inositol trisphosphate G protein-coupled receptor (GPCR)-phospholipase C (PLC)-inositol trisphosphate receptor (IP3R)-SOC signaling
- Plenary Lecture | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
that arrestin can mediated AT1R/TRPC3 or M3R/TRPC3 coupling by forming a complex of AT1R/β-arrestin-1/PLCγ