Apoptosis Pathways Spliceosome mutations are associated with clinical response in a phase 1b/2 study of the PLK1

elevation produced by GCGR activation and promotes expression of phosphoenolpyruvate carboxykinase 1 (PCK1 We verify endocytosis-dependent induction of PCK1 expression by endogenous GCGRs in primary hepatocytes

mGluR5), can lead to sustained calcium signaling and activation of transcription factors like CREB and Elk1

Immunology Spliceosome mutations are associated with clinical response in a phase 1b/2 study of the PLK1 decitabine in relapsed or refractory acute myeloid leukemia Published date November 1, 2023 Abstract "PLK1 A phase 1b trial of the PLK1 inhibitor onvansertib (ONV) combined with decitabine (DAC) demonstrated PLK1 inhibition with ONV in combination with DAC could be a potential therapy in R/R AML patients, particularly Silberman , Eunice S Wang , Amer M Zeidan Tags AML , Biomarker , Hypomethylating agents , Onvansertib , PLK1

quantification (iTRAQ) analysis, and we found that GPR50 promoted HCC was closely related to CCT6A and PGK1 Taken together, GPR50 may promote HCC progression via CCT6A-induced proliferation and PGK1-induced migration

monkey kidney epithelial cells (Vero) and Lilly Laboratories cell-porcine kidney 1 epithelial cells (LLC-PK1