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6 items found for "PLK1"

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📰 GPCR Weekly News, October 30 to November 4, 2023
Apoptosis Pathways Spliceosome mutations are associated with clinical response in a phase 1b/2 study of the PLK1
Glucagon receptor-mediated regulation of gluconeogenic gene transcription is endocytosis-dependent..
elevation produced by GCGR activation and promotes expression of phosphoenolpyruvate carboxykinase 1 (PCK1 We verify endocytosis-dependent induction of PCK1 expression by endogenous GCGRs in primary hepatocytes
An overview of the compartmentalized GPCR Signaling: Relevance and Implications
mGluR5), can lead to sustained calcium signaling and activation of transcription factors like CREB and Elk1

Spliceosome mutations are associated with clinical response in a phase 1b/2 study of the PLK1 inhibitor onvansertib in combination with decitabine in relapsed or refractory acute myeloid leukemia
Immunology Spliceosome mutations are associated with clinical response in a phase 1b/2 study of the PLK1 decitabine in relapsed or refractory acute myeloid leukemia Published date November 1, 2023 Abstract "PLK1 A phase 1b trial of the PLK1 inhibitor onvansertib (ONV) combined with decitabine (DAC) demonstrated PLK1 inhibition with ONV in combination with DAC could be a potential therapy in R/R AML patients, particularly Silberman , Eunice S Wang , Amer M Zeidan Tags AML , Biomarker , Hypomethylating agents , Onvansertib , PLK1
High expression of GPR50 promotes the proliferation, migration and autophagy of hepatocellular carcinoma cells in vitro
quantification (iTRAQ) analysis, and we found that GPR50 promoted HCC was closely related to CCT6A and PGK1 Taken together, GPR50 may promote HCC progression via CCT6A-induced proliferation and PGK1-induced migration
Coronavirus Porcine Epidemic Diarrhea Virus Utilizes Chemokine Interleukin-8 to Facilitate Viral Replication by Regulating Ca2+ Flux
monkey kidney epithelial cells (Vero) and Lilly Laboratories cell-porcine kidney 1 epithelial cells (LLC-PK1