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Until recently, itch pathophysiology was poorly understood and treatments were poorly effective in relieving

desensitized PAR2 have been misconceived as antagonists, and this has impeded a better understanding of the pathophysiological uniquely modulates PAR2-mediated cellular signaling and is a useful pharmacological tool for studying the pathophysiological

August 2022 "Aims: The pathophysiological mechanism(s) underlying non-alcoholic fatty liver disease (

Although GPCRs are implicated in the pathophysiology of Alzheimer's disease (AD), biased GPCR signaling Here, we generated a G protein-biased GPR3 mouse model to investigate the physiological and pathophysiological

Emerging evidence suggests that G protein-coupled receptor (GPCR) kinases (GRKs) are associated with the pathophysiology

GPCRs are involved in a variety of physiological and pathophysiological processes.

Much remains to be known regarding the details of neuropeptide signaling and how it contributes to pathophysiology

this review, we discuss what is currently known regarding the contribution of mGluR2 and mGluR3 to the pathophysiology

the historic context of pepducin development for each receptor, as well as the structural, signaling, pathophysiologic

molecular mechanism for the brain-region-specific modulation of TrkB functions during development and under pathophysiological

The human islet GPCRome is not a static entity, but one that is altered under pathophysiological conditions

maintaining good health since they have a substantial participation in a wide variety of processes of human pathophysiology

expression by any leukocyte type and, if correct, would change current concepts of ACKR1 involvement in pathophysiology

The pathophysiology is not fully understood, but the working hypothesis postulates that a combination

Therefore, a better understanding of the pathophysiology of hepatic fibrosis and the development of related

discovery – opportunities and threats Given the functional relevance of ORs in different physiological and pathophysiological Finally, direct evidence that ectopically expressed OR drives pathophysiological processes remains a

hypertension, this highlights the potential for GRK2 to promote VSMC growth and exacerbate hypertensive pathophysiological

GPCRs in Cardiology, Endocrinology, and Taste Clinical, Pathophysiologic, Genetic, and Therapeutic Progress

GPCRs in Cardiology, Endocrinology, and Taste Pathophysiology and pharmacology of G protein-coupled receptors

Neuroscience GPCR interactions involving metabotropic glutamate receptors and their relevance to the pathophysiology

Structural Biologist Senior Scientist/Staff Scientist, Computational Chemistry GPCR Activation and Signaling Pathophysiological

topics in GPCR research from 'Down Under' Apelin receptor dimer: Classification, future prospects, and pathophysiological

C. elegans GPCR interactions involving metabotropic glutamate receptors and their relevance to the pathophysiology

synaptic transmission The multifaceted role of the CXC chemokines and receptors signaling axes in ALS pathophysiology

Given their pathophysiological significance in pain, addiction and depression opioid receptors represent

GPCRs in Oncology and Immunology Clinical, pathophysiologic, genetic and therapeutic progress in Primary

phospho-drug-associated pruritus in a humanized mouse model GPCRs in Cardiology, Endocrinology, and Taste The Genetic Pathophysiology

scavenging role however to fully understand the role of canonical chemokine receptors scavenging population pathophysiology