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137 items found for "Pei Ling Chia"
Posts (75)
- Verily links up with Sosei Heptares for GPCR drug discovery
January 2022 "G-protein-coupled receptors’ star has been on the rise in biotech in recent years as researchers have discovered the vast potential for GPCR-targeting drugs in treating a range of health conditions, from cancer and genetic disorders to inflammation and metabolic imbalances. Among those hitching their wagons to that star are Verily and Sosei Heptares , which have struck a research agreement to discover new GPCR targets that’ll fuel the development of potential drug candidates. The financial details of the strategic collaboration weren’t released, but Sosei Heptares ’ past two team-ups in GPCR-based drug discovery have clocked in at $1 billion—with Genentech—and, just last November, $2.6 billion in a partnership with Neurocrine." Read more at the source #DrGPCR #GPCR #IndustryNews
- ADGRL3 genomic variation implicated in neurogenesis and ADHD links functional effects to the...
October 2022 ADGRL3 genomic variation implicated in neurogenesis and ADHD links functional effects to GIP has been linked to the pathogenesis of diabetes mellitus, and our analyses suggest a potential link
- Integrative model of the FSH receptor reveals the structural role of the flexible hinge region
Structurally, the extensive extracellular domain, which contains the hormone-binding site and is linked to the transmembrane domain by the hinge region (HR), is characteristic for these receptors.
Other Pages (62)
- Exploiting frequent and specific expression of PRL3 in pediatric solid tumors for first-in-child use of PRL3-zumab humanized antibody
Hern Wang Cheng , Arjandas Mahadev , Matthew Chau Hsien Ng , Michaela Su-Fern Seng , Prasad Iyer , Pei Ling Chia , Shui Yen Soh , Qi Zeng Tags PRL3 , PTP4A3 , PRL3-zumab , Wilms tumor , neuroblastoma , non-rhabdomyosarcoma
- Orphan receptor GPR50 attenuates inflammation and insulin signaling in 3T3-L1 preadipocytes
Furthermore, GPR50 knockout in the 3T3-L1 cell line suppressed PPAR-γ expression. Authors Zhenyu Yao, Jun Meng, Jing Long, Long Li, Weicong Qiu, Cairong Li, Jian V Zhang, Pei-Gen Ren
- Session VIII | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
AGPCRs in the periphery ADGRG1/GPR56 regulates survival of terminally differentiated CD8+ T cells Cheng-Chih disease Douglas Tilley ADGRG1/GPR56 regulates survival of terminally differentiated CD8+ T cells Cheng-Chih Hsiao Abstract Only available for AGPCR 24 Attendees Authors & Affiliations "Cheng-Chih Hsiao1,2, Hendrik Departments of Neurology and Immunology, Erasmus Medical Center, Rotterdam, The Netherlands" About Cheng-Chih Netherlands Institute for Neuroscience; 2022 - present: Researcher associate, Netherlands Brain Bank" Cheng-Chih