Hansen et a l has introduced a sensitive method for detecting GPCR mRNAs in human immune cells and platelets reports that human white blood cells express an average of 160 GPCR mRNAs, ranging from 123 to 206, while platelets Therefore this study significantly advances our understanding of GPCR expression in human immune cells and platelets

September 2022 "Platelets are well characterized for their indispensable role in primary hemostasis to Research over the past years has provided a substantial body of evidence demonstrating that platelets The surface expression of pattern recognition receptors, such as TLR2 and TLR4, provides platelets with Platelet α-granules contain microbicidal proteins, chemokines and growth factors, which upon release In particular, platelets can activate neutrophils to form neutrophil extracellular traps (NETs).

September 2022 "Introduction Protease activated receptors 1 (PAR1) and 4 (PAR4) agonists are used to study platelet Data on platelet activation are extrapolated across experimental settings. C1-inhibitor (C1INH) is a protease inhibitor present in plasma but not in isolated platelet suspensions Here we show that C1INH affects platelet activation through PAR1 and PAR4 agonists. The platelet suspensions were exposed to PAR1 agonists SFLLRN, TFLLR and TFLLRN; PAR4 agonists AYPGKF

under Shear "Glycoprotein (GP)VI and integrin αIIbβ3 are key signaling receptors in collagen-dependent platelet PTK2 inhibition or of pGRP with pCIB > pCIBm in additive ways suppressed collagen- and GPVI-dependent platelet

Monserrat Avila-Zozaya , our incredible contributor, for her fantastic article on Profiling Immune Cell and Platelet receptor subunit interactions are modulated by agonists and determine signaling Distinct role of GRK3 in platelet

Receptor GPCRs in Cardiology, Endocrinology, and Taste Sodium/Potassium ATPase Alpha 1 Subunit Fine-tunes Platelet

wide spectrum of endocrine tumors G protein coupled receptor transcripts in human immune cells and platelets

Platelet P2Y1 receptor exhibits constitutive G protein signaling and β-arrestin 2 recruitment.