receptor-related gene signature through bioinformatics analysis to construct a risk model for ovarian cancer prognosis Inefficient early diagnosis and prognosis leads to poor survival in most patients. We aimed to identify GPCR-related gene (GPCRRG) signatures and develop a novel model to predict OV prognosis Results: Based on the risks scores, 17 GPCRRGs were associated with OV prognosis. prognosis and immune response prediction in patients with OV."

explore the relationship between GPR37 gene expression and the clinicopathological factors, patient prognosis significantly higher in the glioma tissues compared to the normal brain tissues, and was linked to poor prognosis positively correlated with increased infiltration of M2 macrophages, which in turn was associated with poor prognosis Finally, hypomethylation of the GPR37 promoter was associated with its high expression levels and poor prognosis Yanbin Ke , Zhaotao Wang , Yezhong Wang Tags GPR37 , M2 macrophages , glioma , immune infiltration , prognosis

GPCR News < GPCRs in Oncology and Immunology SSTR2 positively associates with EGFR and predicts poor prognosis belongs to the receptor tyrosine kinases family and overexpression of EGFR has been linked to poor prognosis expression of SSTR2, high expression of EGFR, and high coexpression of SSTR2 and EGFR had a poorer prognosis expression of EGFR, high coexpression of EGFR and SSTR2, and EGFR/SSTR2 anyone high expression had a better prognosis Additionally, SSTR2 has potential as a new biomarker for poor prognosis in NPC patients."

GPCRs in Oncology and Immunology PAXIP1-AS1 is associated with immune infiltration and predicts poor prognosis in OC cell lines, but the relationship between PAXIP1-AS1 expression and clinical characteristics, prognosis were used to evaluate the relationship between clinical characteristics and PAXIP1-AS1 expression, prognostic PAXIP1-AS1 could be a promising prognosis biomarker and response to immunotherapy for OC."

< GPCR News < GPCRs in Oncology and Immunology Exploration of prognostic and treatment markers in hepatocellular (HCC) was elucidated, and GPCR-related genes were employed for building a risk-score model for the prognosis Patients in the high-risk group exhibited a worse prognosis but demonstrated a more favorable immunotherapy Conclusions: In this study, an efficient HCC prognostic prediction model was constructed by only GPCR-related , Jiali Xing , Baoluhe Zhang , Xiaokun Chen , Xiao Liu , Xueshuai Wan , Shunda Du Tags GPCR ; HCC ; Prognosis

News < GPCRs in Oncology and Immunology Identification of S1PR4 as an immune modulator for favorable prognosis

We investigated the prognostic values of the guanine nucleotide-binding protein G(i) alpha subunit (GNAI association in the tumor microenvironment between the gene expression of GNAI subunit 3 (GNAI3) and a poor prognosis Our findings suggest that the GNAI3 gene holds potential as a prognostic biomarker for GBM. Tags G-protein-coupled receptor (GPCR) , genome , glioblastoma , malignancy , molecular biomarker , prognosis

June 24, 2024 Abstract "Pancreatic ductal adenocarcinoma (PDAC) remains a dreadful disease with poor prognosis While the prognosis of colorectal carcinoma (CRC) is better than that of PDAC, it still is the second-leading

tumors, particularly in non-small-cell lung cancer (NSCLC) METHODS: We explored the expression and prognosis We found that elevated GPR37 expression predicts an unfavorable prognosis. (2) It was demonstrated that

and clinical significance of beta 2-adrenergic receptor in oral squamous cell carcinoma: an emerging prognostic is significantly overexpressed in various types of malignancies, which is associated with the worst prognosis In the Cox proportional hazards model, β2-AR was identified as a prognostic biomarker of OSCC (p = 0.047 Conclusion: β2-AR protein level is identified as an independent significant prognostic factor in patients Mohanty, Rajender Singh, Vijay Kumar, Uma Shankar Singh, Rakesh Kumar Singh Tags GPCR; OSCC; Oral cancer; Prognostic

Several studies have suggested that SCI-IDS is an independent risk factor for poor neurological prognosis immunosuppression in the periphery results in increased susceptibility to infection, leading to poor neurological prognosis

specifically expressed on tumor cells from lung adenocarcinoma (LUAD) patients, closely related to their prognosis

associated with accelerated progression of glioblastomas, aggressive brain tumors with a generally poor prognosis

cancers, and its levels in prostate cancer significantly correlate with the metastatic stage and poor prognosis

899 CRC tissues revealed elevated RGS16 levels, correlating with clinicopathological features and CRC prognosis

cancer cell lines and cancer tissues and that coexpression of CXCR4 and HRH1 is associated with poor prognosis

3, 2023 Abstract " Purpose: Peripheral T-cell lymphoma (PTCL) is an aggressive disease with a poor prognosis

Our study aimed to identify the role of RGS20 in NSCLC prognosis and delineate associated cellular and

We found several genes that are known PCa prognostic factors or biomarker to be differentially expressed

findings shed light on the potential of non-canonical odorant receptors as therapeutic targets and prognostic

Survival analysis established the clinical prognostic relevance of identified hub genes in cancer.

correlates with survival outcomes and therapy response in ovarian cancer clinical samples, underscoring its prognostic

PR is an important prognostic factor in breast cancer.

of CELSR1, which would be missed in gene expression microarray analyses, we hope to illuminate the prognostic

Before joining UAB as a graduate student, he worked in the EuGEF Research Group to identify novel prognostic