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September 2022 Exploiting Dependence of Castration-Resistant Prostate Cancer on the Arginine Vasopressin Signaling Axis by Repurposing Vaptans "Men with advanced prostate cancer are treated by androgen deprivation therapy but the disease recurs as incurable castration-resistant prostate cancer (CRPC), requiring new Interrogation of prostate cancer patient sample data revealed that coexpression of AVPR1A and AVPR2 is

whereas OR51E1 and OR51E2 represent ubiquitously expressed ORs, although there are highly increased in prostate tissue, especially in prostate cancer (Maßberg D. and Hatt H. 2018). OR51E1 and OR51E2, initially assumed to be GPCRs only expressed in prostate tissue, play a role in prostate cancer epithelial cells proliferation via activation by β-ionone which initiates prostate cancer cell

more Elucidation of active components and target mechanism in Jinqiancao granules for the treatment of prostatitis and benign prostatic hyperplasia GPCRs in Cardiology, Endocrinology, and Taste Blockade of endothelial

Immunology Elucidation of active components and target mechanism in Jinqiancao granules for the treatment of prostatitis and benign prostatic hyperplasia Published date June 28, 2024 Abstract " Ethnopharmacological relevance : Prostatitis and benign prostatic hyperplasia (BPH) are inflammations of the prostate gland, which surrounds Aim of the study: We hypothesized that Jinqiancao granules could be a potential therapy for prostatitis hyperplasia , G-protein coupled receptor , Jinqiancao granules , Network pharmacology , Prostatitis

GPCR News < GPCRs in Oncology and Immunology Autocrine proteinase-activated receptor signaling in PC3 prostate

of the R4 family of RGS proteins, is overexpressed in many solid breast cancers, and its levels in prostate In addition, AJ-3 inhibited the migration of LNCaP prostate cancer cells in wound healing assays.