< GPCR News < GPCRs in Oncology and Immunology GPR97 depletion aggravates imiquimod-induced psoriasis pathogenesis via amplifying IL-23/IL-17 axis signal pathway Published date September 10, 2024 Abstract "Skin psoriasis This autoimmune loop in psoriasis pathogenesis is influenced by G protein-coupled receptor (GPCR) signalling transduction, and in particular, function of adhesion molecule GPR97 in psoriasis endures to be utterly It was found that significantly aggravated psoriasis-like lesion in GPR97-/- mice.

This pathway is implicated in mechanisms related to many diseases, such as cancer, psoriasis, multiple