GPCRs in Cardiology, Endocrinology, and Taste GPR97 deficiency ameliorates renal interstitial fibrosis Transcriptomic analysis of human cytomegalovirus to survey the indirect effects on renal transplant recipients

August 2022 A NanoBRET-Based H 3 R Conformational Biosensor to Study Real-Time H 3 Receptor Pharmacology

on the role of autoantibodies targeting GPCRs in various diseases, such as cardiovascular diseases, renal

to be discussed and to be put in context as soon as possible to be up-to-date and to accelerate the translation

HCC (p < 0.001), RGS20 was found to be an important factor for survival in four other cancers (clear renal

GPR97 deficiency ameliorates renal interstitial fibrosis in mouse hypertensive nephropathy. Molecular Pharmacology, Discovery Biology Staff Scientist/Senior Staff Scientist, Disease Biology and Translational

Novartis bolsters innovative medicines strategy and renal pipeline with agreement to acquire Chinook

protein-coupled receptor GPR52 Endosome positioning coordinates spatially selective GPCR signaling GRK5 promoted renal

In the human kidney ORs elicit intracellular Ca2+flux in renal proximal tubule cells via adenylyl cyclase

April 2022 "By Sophie Bradley | Apr 12, 2022 Summary Sophie Bradley, Translational Sciences Associate

August 2022 "A confluence of factors has renewed interest in the scientific understanding and translational

April 2022 "By Cliona MacSweeney | Apr 20, 2022 Cliona MacSweeney, a project director in our Translational

Neuropeptides exhibit distinct characteristics which includes their post-translational processing, release

and should benefit from and contribute to the implementation of the guidelines, together improving translation

We discuss the importance of understanding the translatability of cell and animal models to have more

such as transcriptomics and proteomics have provided insights into the expression patterns and post-translational clinical research has opened new avenues for exploring GPCR biology, developing targeted therapies, and translating

Our study provides mechanistic insights into the regulation of aGPCRs via post-translational modifications

While more work is needed to further elucidate the translational value of selectively targeting CB2 receptors

"New team focused on expanding its GPCR-focused structure-based drug design platform and enhancing translational

In addition, the molecular mechanisms underlying GPCR-induced post-translational signaling regulation

Erythrocytes are terminally differentiated anuclear cells with no transcription and limited translation

challenges in the study of GPCR action in multiple systems, but also offers exciting opportunities in the translational

Topics cover new cellular assays, real-time kinetics, and unique GPCR behaviors. Special Issue of Molecular Pharmacology GPCR Events, Meetings, and Webinars September 5 - 6, 2024 | 4th Transatlantic

GPCR Events, Meetings, and Webinars ONCORNET2.0 Final Symposium (August 31 - September 1, 2023) 3rd Transatlantic

advanced AI models like AlphaFold3, which can predict complex protein-molecule interactions and post-translational

Molecular Pharmacology, Discovery Biology Staff Scientist/Senior Staff Scientist, Disease Biology and Translational

October 31, November 7 - 14 -21, and December 5, 2024 (five sessions) Topics:  New cellular assays, real-time Possibilities in GLP-1R Drug Discovery GPCR Events, Meetings, and Webinars September 5 - 6, 2024 | 4th Transatlantic

cellular assays to analyze GPCR ligand behavior Predicting activity and in vivo target coverage with real-time Intralinks’ Virtual Data Room   GPCR Events, Meetings, and Webinars NEW September 5 - 6, 2024 | 4th Transatlantic