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25 items found for "Renal transplantation"
- Transcriptomic analysis of human cytomegalovirus to survey the indirect effects on renal transplant recipients
transplant recipients Published date May 30, 2023 Abstract "Post-transplant human cytomegalovirus (HCMV ) viremia has been linked to adverse "indirect effects" among transplant patients. Objective: In the present study, the RNA-Seq whole transcriptome of renal transplant (RT) patients was HCMV active infection and could be linked to the adverse indirect effects caused by HCMV infection in transplant Tags Human cytomegalovirus , Indirect effects , RNA-Seq , Renal transplantation , Transcriptome .
- Noval insights and therapeutic strategies for tumor-induced kidney pathologies
hormones in Drosophila models has provided valuable insights into the mechanisms underlying tumor-induced renal G protein-coupled receptor TkR99D in fruit flies, as a potential therapeutic target for alleviating renal of TACR3 and provided an in-depth analysis of cell type specific expression of TACR3 in response to renal injury and expressional dynamics during renal carcinoma progression. The implications of these findings for transforming the therapeutic approaches to renal complications
- Ovarian cancer G protein-coupled receptor 1 (OGR1) deficiency exacerbates crystal deposition and kidney injury in oxalate nephropathy in female mice
These receptors have various physiological and pathophysiological roles in renal acid-base physiology Their function in injured renal tissue, however, remains mostly unclear. . After 10 days of high-oxalate intake and 4 days of recovery, renal crystal content, histopathology
- Session VIII * | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
also highly expressed in the kidney, however, little is known about the function of this receptor in renal To provide the molecular basis for the renal phenotype, we analyzed in parallel differential expression The change in protein expression of key proteins including VEGFA is associated with the abnormal renal system phenotype such as learning and memory deficit and BBB dysfunction, our study revealed a new renal
- Exploiting frequent and specific expression of PRL3 in pediatric solid tumors for first-in-child use of PRL3-zumab humanized antibody
in neuroblastoma (100%), rhabdomyosarcoma and non-rhabdomyosarcoma soft tissue sarcomas (71%), and renal
- Ep 155 with Endocrine Metabolic GPCR Organizers
research focused on the cellular mechanisms by which mutations in a chloride-proton antiporter cause the renal
- Posters | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
This mouse model will be useful to delineate the collecting duct-specific role of GPR56 for renal function During my graduate studies, using various transgenic mouse models and expertise in intestinal and renal training, I have continued to develop my expertise to answer fundamental questions on adhesion GPCR in renal Neuroscience at American University in Washington, DC and her dual-title PhD in Neuroscience and Clinical and Translational
- Student Flash Presentations | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Gentile, Alessandra2; Petersen, Sarah C.3; Stainier, Didier Y.R.2; Engel, Felix B.1 1 Experimental Renal However, the molecular details underlying their activation and how mechanical forces are translated into Renal Adgrf5 is restricted to two distinct populations of cells: AICs and endothelial cells (ECs). We hypothesized that cell-specific Adgrf5 transcript variants are expressed in renal AICs and ECs, and
- Ep 148 with Dr Arthur Christopoulos
They also explored the significance of translating fundamental discoveries into clinical applications Collaborative Research and Translational Approach Arthur and Yamina from Monash University discussed Additionally, they explored the unique culture and structure of their Institute, highlighting its translational approach to research and its capacity to translate research into therapeutic commercialization. Translating Discovery Into Clinical Application Arthur and Yamina discussed the importance of translating
- Ep 71 with Dr. Jean Martin Beaulieu
Translational validation is important to validate findings obtained from experimental models research In addition to basic research, the Beaulieu group is also actively implicated in translational research
- Interrogating Multiscale Receptors Functions in Space
Translational validation is important to validate findings obtained from experimental models research In addition to basic research, the Beaulieu group is also actively implicated in translational research
- GPCR Retreat Logo Contest | Dr. GPCR Ecosystem
fields of study encompassing GPCR research, such as biochemistry, pharmacology, structural biology, and translational
- Ep 95 with Chris Langmead
editorial boards of the British Journal of Pharmacology, ACS Chemical Neuroscience, ACS Pharmacology & Translational
- Ep 103 with Dr Kathleen Caron
also past Associate Editor at JCI and served as the inaugural Associate Editor at ACS-Pharmacology and Translational
- Ep 104 with Dr. Raul Gainetdinov
Gainetdinov is the Institute of Translational Biomedicine Director at Saint Petersburg State University
- Ep 78 with Dr. Stuart Maudsley
At the NIH he was the recipient of the coveted NIH ‘Bench-to-Bedside’ Translational Research Grant Award
- Pharmacological and Genetic Preclinical Models of Ghrelin Receptor Functional Selectivity to Investigate Metabolic Disease Pathophysiology
Biology, Duke Trinity College of Arts and Sciences, Durham, NC 27710. 3-National Center for Advancing Translational
- GPCR signaling contributes to immune characteristics of microenvironment and process of EBV-induced lymphomagenesis
Collectively, our study identified a previously unknown GPCR-mediated malignant progression and translated
- Regulator of G protein signaling 16 restrains apoptosis in colorectal cancer through disrupting TRAF6-TAB2-TAK1-JNK/p38 MAPK signaling
study provides insights into addressing the challenges posed by CRC, offering avenues for clinical translation
- The pyruvate-GPR31 axis promotes transepithelial dendrite formation in human intestinal dendritic cells
G-protein-coupled receptors (GPCRs) sense metabolites and can act as key mediators that translate gut
- Ep 47 with Dr Simone Promel Dr Ines Liebscher
questions of how Adhesion GPCRs integrate the different signals on a molecular level and how these are translated
- GPCR Retreat 2023 | Dr. GPCR Ecosystem
and diverse GPCR scientists working in the arenas of structure and signaling, neuroscience, cancer, translational
- Session II | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
His research aims to translate these novel agents to testing in clinical trials with the hope to develop GPCR signaling and trafficking can be regulated by several different post-translational modifications
- Session IV | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
of Sheffield followed up by obtaining a PhD in molecular neuroscience at the Sheffield Institute for Translational
- Content and Conduct Policy | Dr. GPCR Ecosystem
perpetual, irrevocable, worldwide, royalty-free, and non-exclusive license to reproduce, adapt, modify, translate By "use" we mean use, copy, publicly perform and display, reproduce, distribute, modify, translate, remove