Search Results
33 items found for "Roberto P Garofalo"
- Chemokine Cxcl1-Cxcl2 heterodimer is a potent neutrophil chemoattractant
Authors Kirti V Sawant , Krishna Mohan Sepuru , Brigith Penaranda , Emily Lowry , Roberto P Garofalo
- Expression pattern and clinical significance of beta 2-adrenergic receptor in oral squamous cell carcinoma: an emerging prognostic indicator and future therapeutic target
higher in the case group as compared to the control group (positivity 40.31 ± 3.01 vs. 20.46 ± 1.93, p < 0.001; density 2.77 ± 1.17 vs. 1.28 ± 0.37, p < 0.001). mRNA level was also upregulated in patients compared to the controls (2.36 ± 1.30 vs. 1.09 ± 0.42, p < 0.001) and showed a positive correlation with immunostaining of protein in OSCC (r = 0.48, p = 0.011 differentiation (p = 0.013), clinical TNM stages (p = 0.014), and poor survival (p = 0.006) of patients
- Comparison of infectious complications with BCMA-directed therapies in multiple myeloma
significantly lower with CAR-T compared to BsAb at 1-year (incidence-rate-ratio [IRR] = 0.43, 95%CI 0.25-0.76, P treatment-emergent hypogammaglobulinemia, BsAb recipients had higher infection rates (IRR:2.27, 1.31-3.98, P = 0.004) and time to severe infection (HR 2.04, 1.05-3.96, P = 0.036) than their CAR-T counterparts. During periods of non-neutropenia, CAR-T recipients had a lower risk (HR 0.44, 95%CI 0.21-0.93, P = 0.032 ) and incidence rate (IRR:0.32, 95% 0.17-0.59, P < 0.001) of severe infections than BsAb.
- Severity of neurological long-COVID symptoms correlates with increased level of autoantibodies targeting vasoregulatory and autonomic nervous system receptors
of evaluated autoantibodes were significantly higher in Long-COVID compared to the 2 other groups (p higher number of patients with simultaneous detection of more than one autoantibody in Long-COVID group (p ARB1 and ARB2 correlated negatively CERAD Trail Marking A and B (R ≤ -0.26, p ≤ 0.043), while CHRM3 correlated positively with Chadler Fatigue Scale (R = 0.37, p = 0.0087).
- Molecular docking and dynamics simulation studies uncover the host-pathogen protein-protein interactions in Penaeus vannamei and Vibrio parahaemolyticus
However, Vibrio parahaemolyticus infection poses a major challenge in ensuring the success of P. vannamei conducted to identify the interaction sites and binding affinity between several immune-related proteins of P. The P. vannamei-V. parahaemolyticus protein-protein interaction of Complex 1 (Ferritin-HrpE/YscL family simulation analysis, which revealed these complexes greatly contribute to the interactions between P.
- The GPCR-Gαs-PKA signaling axis promotes T cell dysfunction and cancer immunotherapy failure
Authors Victoria H Wu , Bryan S Yung , Farhoud Faraji , Robert Saddawi-Konefka , Zhiyong Wang , Alexander Rebecca Berdeaux , Dario A A Vignali , Ramiro Iglesias-Bartolome , Hannah Carter , Eytan Ruppin , Jill P
- Ep 97 with Robert Laprairie
GPCR Podcast << Back to podcast list Robert Laprairie About Dr. Robert Laprairie Dr. Robert Laprairie is an Associate Professor and the Saskatchewan Research Chair in Drug Discovery and Robert Laprairie on the web University of Saskatchewan Twitter Instagram ResearchGate Google Scholar
- Removing the GPCR-mediated brake on exocytosis enhances insulin action, promotes adipocyte browning, and protects against diet-induced obesity
obesity Date & Time Friday, November 3rd / 2:45 PM Abstract Coming Soon Authors and Affiliations Ryan P. Ayala 5, Owen P. McGuinness 5, Sheila Collins 1,5, Heidi E.
- Ep 27 with Dr. Robert J. Lefkowitz
Robert J. Well, it’s the one and only Robert J. pressed record, I asked if I could call him Bob, and he answered that only his mom used to call him Robert Robert J.
- Ep 114 with Dr. Robert F. Bruns
Robert F. Bruns About Dr. Robert F. Robert F. Bruns on the web ResearchGate LinkedIn Dr.
- Ep 57 with Dr. Peter Robert Banks
Peter Robert Banks About Dr. Peter Robert Banks Peter Banks is currently the Scientific Director at BioTek Instruments , now a part Peter Robert Banks on the web LinkedIn Dr.
- Increased protease-activated receptor 1 autoantibodies are associated with severe COVID-19
Kristina Sterner , Susanne Schinke , Nadja Käding , Jens Y Humrich , Otávio Cabral-Marques , Joana P
- Neuroimmune interplay during type 2 inflammation: symptoms, mechanisms and therapeutic targets in atopic diseases
gamma-AS1 , Interferon regulatory factor 1 , Interferon-gamma , Interleukin , Interleukin-1 receptor alpha P Sialic-acid-binding immunoglobulin-like lectin 8 , Signal transducer and activator of transcription , Substance P
- Posters | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Functional Coupling Between Extracellular and Transmembrane Regions of a Holo-Adhesion GPCR Szymon P. Functional Coupling Between Extracellular and Transmembrane Regions of a Holo-Adhesion GPCR Szymon P. affiliation: Department of Structural Biology, Genentech, South San Francisco, CA, USA" About Szymon P. Szymon P. Hernández-Aranda Judith 2, Correoso-Braña Kerlys 1, Vialou Vincent 3, Leduc Richard 4, Olivares-Reyes Jesús Alberto
- CB2 stimulation of adipose resident ILC2s orchestrates immune balance and ameliorates type 2 diabetes mellitus
Shafiei-Jahani, Shi Yan, Mohammad H Kazemi, Xin Li, Amitis Akbari, Kei Sakano, Yoshihiro Sakano, Benjamin P
- C-Principles2 (List) | Dr. GPCR Ecosystem
T>P> Kenakin, Elsevier or ''A Pharmacology Primer' (6th ed.) T.P. Kenakin, Elsevier.
- Spliceosome mutations are associated with clinical response in a phase 1b/2 study of the PLK1 inhibitor onvansertib in combination with decitabine in relapsed or refractory acute myeloid leukemia
Authors Peter J P Croucher , Maya Ridinger , Pamela S Becker , Tara L Lin , Sandra L Silberman , Eunice
- Inhibition of Relaxin Autocrine Signaling Confers Therapeutic Vulnerability in Ovarian Cancer
Vulnerability in Ovarian Cancer Date & Time Friday, November 3rd / 3:55 PM Abstract Coming Soon About Robert Robert Rottapel on the web The Rottapel Lab Ontario Institute for Cancer Research University of Toronto
- Functional Assessment of Cancer-Linked Mutations in Sensitive Regions of Regulators of G Protein Signaling Predicted by Three-Dimensional Missense Tolerance Ratio Analysis
Subsequent permutation analysis can define the protein regions that are most significantly intolerant ( P
- Ep 68 with Dr. Matthew Eddy
Robert Griffin . Following this, Dr.
- Full Agenda for Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Lunch Read More 2:00 PM Posters Caroline Formstone · Jianxiang Xue · Virginea de Araujo Farias · Szymon P. Anti-Tumorigenic Role of Brain Angiogenesis Inhibitor 3 (BAI3) in WNT-Activated Medulloblastomas Szymon P.
- Ep 49 with Dr. Sudha Shenoy
Robert J. Lefkowitz (Nobel Laureate, 2012) at Duke University. Dr.
- Ep 100 with Dr Caron Tribute Part 1
Robert Lefkowitz (1973) Dr. Lee Limbird (1973) Dr.
- Distinct sub-cellular signal propagation as a component of functional selectivity
same university in 1985, he completed a post-doctoral fellow at Duke University in the laboratory of Robert
- Ep 130 with Dr. Richard Premont
In 1992, he won a Helen Hay Whitney Foundation fellowship to support his post-doctoral work with Robert
- Ep 72 with Dr. Stuart Maudsley
Maudsley was awarded a Howard Hughes Medical Institute Fellowship to train with Professor Robert Lefkowitz
- Ep 131 with Dr. Richard Premont
In 1992, he won a Helen Hay Whitney Foundation fellowship to support his post-doctoral work with Robert
- Ep 78 with Dr. Stuart Maudsley
Maudsley was awarded a Howard Hughes Medical Institute Fellowship to train with Professor Robert Lefkowitz