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20 items found for "Shan-He Yu"
- GPCR Therapeutics welcomes Dr. Ed Brennan as their new Vice President, Head of Clinical Development
He has led teams that have filed more than 10 Investigational New Drug Applications (IND), as well as In 2007 he formed IndiPharm which was a full-service Contract Research Organization whose operational He received his undergraduate Bachelor of Science Degree in Pharmacy from The Philadelphia College of He went on to study medicine at the Royal College of Surgeons in Ireland before receiving his Medical
- Drug Discovery Picks Up the Pace, Stays on Target
After all, he also complained that the perfect is the enemy of the good. He might reverse himself and declare that the perfect can in fact be the friend of the good.
- 🎧Episode 85 of the Dr. GPCR podcast is here!
Nicholas Holliday and how he has combined his university role with his leadership of Excellerate Bioscience
- Mark Schmeizl - Dr. GPCR Podcast
He is a pro at Matchmaking the top talent in the life sciences with the industry’s leading companies.
- Jan Steyaert Named 2022 Jacob and Louise Gabbay Award Winner
Jan Steyaert will be presented with the Gabbay Award at Brandeis University on October 27 when he will
- Inversago Pharma appoints Glenn S. Vraniak as Chief Financial Officer
Vraniak’s career spans more than 20 years of financial and commercial experience in the life sciences an executive in various innovative healthcare and technology companies including GE Capital, where he
- Decoding GPCR Function: The Role of Mutagenesis in Rational Drug Discovery
Additionally, deep mutational scanning can generate large-scale datasets, allowing researchers to determine Deep mutational scanning: a new style of protein science. Nature Methods , 11 (8), 801-807.
- Molecular basis for variations in the sensitivity of pathogenic rhodopsin variants to 9-cis-retinal
In this work, we utilize deep mutational scanning to quantitatively compare the plasma membrane expression
- Exendin-4 Attenuates Remodeling in the Remote Myocardium of Rats After an Acute Myocardial ...
Methods: Rats were divided into sham, sham + Exendin-4 (10 μg/day, i.p), MI, and MI + Exendin-4.
- Artificial intelligence – faster, smarter, cheaper GPCR drug discovery
BRS-3D was used to predict subtype-selective ligands for dopamine receptors and adenosine receptors (He , Ben, Kuang, Wang & Kong, 2016; Kuang, Feng, Hu, Wang, He & Kong, 2016). 5.
- From DNA day to GPCR genomics
., He, F., Maul, L., Gmeiner, P., Kobilka, B. K., Hildebrand, P. W., & Skiniotis, G. (2023).
- Targeted Drug Design through GPCR Mutagenesis: Insights from β2AR
Deep mutational scanning, for instance, is gaining popularity as a strategy due to its ability to comprehensively
- Unlock the Future of GPCR Science: Breakthroughs and Courses Await | Sep 2 - Sep 8, 2024
Terry Kenakin as he shares insights into what you can anticipate for the upcoming courses.
- 📰 GPCR Weekly News, February 5 to 11, 2024
Financial Expectations for 2024 Domain Therapeutics further strengthens leadership team with appointment of Sean
- 📰 GPCR Weekly News, April 15 to 21, 2024
Drug Discovery Nexus Salipro Biotech will participate in BioKorea2024 Domain Therapeutics Appoints Sean
- Overview of adhesion GPCRs self-activation
each G protein with the receptor showed that there are more polar interactions in Gq/Gs engagements than Xu, Z., Xia, R., Liang, J., Duan, Y., Yin, H., Xiong, Y., Zhang, A., Guo, C., Chen, Z., Huang, Z., & He
- New role of β-arrestins in MOR signaling
Reeves KC, Shah N, Muñoz B, Atwood BK.
- Ode to GPCRs
neurotransmitters such as dopamine, noradrenaline, and serotonin control neuronal excitability.[55,56] He
- 📰 GPCR Weekly Buzz: Exciting Schedule Shifts for Principles of Pharmacology I & II | August 12-18, 2024
GRK2 kinases in the primary cilium initiate SMOOTHENED-PKA signaling in the Hedgehog cascade Elita Yuliantie
- 📰 GPCR Weekly News, July 1 to 7, 2024
CXV: The Class F of G Protein-Coupled Receptors Yusman Manchanda , Dr. Jianming Han , Tao Che for their analysis of GPCR-G protein selectivity revealed by structural pharmacology Submit your abstract today; you have less than two weeks!