Search Results
57 items found for "Shan-He Yu"
- GPCR signaling contributes to immune characteristics of microenvironment and process of EBV-induced lymphomagenesis
Authors Jie Xiong , Yu-Ting Dai , Wen-Fang Wang , Hao Zhang , Chao-Fu Wang , Tong Yin , Shu Cheng , Hui-Juan Zhong , Shan-He Yu , Lu Jiang , Sheng-Yue Wang , Hai Fang , Rui-Hong Zhang , Yue Zhu , Hong-Mei Yi ,
- Ep 45 with Dr Ralf Jockers
For postdoctoral training, he joined the laboratory of Dr. Strosberg AD in France, where he worked on the regulation of ß-adrenergic receptors. He is the Research director at INSERM with a specific interest in G protein-coupled receptors by developing He showed the formation of melatonin receptor heteromers in vitro and in vivo and their importance in He is a highly cited researcher – 2019 and 2020 identified by Clarivate Web of Science ™. Dr.
- Ep 95 with Chris Langmead
He also directs a collaborative neuroscience R&D program with Servier (France) and is the co-founder company (2009-2012), where he was responsible all of the company’s discovery biology. He is an acknowledged expert in drug discovery, particularly in the field of psychiatry, where he has He has a degree and PhD in pharmacology from Queens' College, Cambridge and University College London He is also a corresponding member of NC-IUPHAR.
- Ep 69 with Dr. Stephen Ferguson
He did B.Sc. in biology at McGill University and received his Ph.D. under the mentorship of Dr. He did his postdoctoral training with Dr. Marc G. He has held four Canada Research Chairs since 2001 and was previously a Heart and Stroke Foundation of He was a recipient of Canada's Top 40 under 40 award in 2004 and received Queen Elizabeth II, Diamond Most recently, in 2021, he was elected as a Fellow of the Canadian Academy of Health Science (FCAHS).
- Ep 70 with Dr. Stephen Ferguson
He did B.Sc. in biology at McGill University and received his Ph.D. under the mentorship of Dr. He did his postdoctoral training with Dr. Marc G. He has held four Canada Research Chairs since 2001 and was previously a Heart and Stroke Foundation of He was a recipient of Canada's Top 40 under 40 award in 2004 and received Queen Elizabeth II, Diamond Most recently, in 2021, he was elected as a Fellow of the Canadian Academy of Health Science (FCAHS).
- Ep 63 with Dr. Khaled Abdelrahman
He joined the laboratory of Dr. William Cole at the University of Calgary in 2010 for his Ph.D. where he studied the molecular basis In 2015, He joined Dr. He has been also studying what aspects of GPCR signaling are regulated in a sex-selective manner and He received the Canadian Society of Pharmacology and Therapeutics Postdoctoral and Publication awards
- Ep 96 with R. Scott Struthers
Prior to Crinetics, he was senior director and head of endocrinology and metabolism at Neurocrine Biosciences At Neurocrine, he initiated and led the effort to discover and develop orally active, nonpeptide GnRH Prior to Neurocrine, from 1995 to 1998, he co-founded ScienceMedia Inc. to develop eLearning solutions In addition, he is a member of the board of directors of the San Diego Entrepreneurs Exchange, a nonprofit organization that provides resources for early-stage start-ups, which he co-founded in [2009.]
- Regulator of G protein signaling protein 6 alleviates acute lung injury by inhibiting inflammation and promoting cell self-renewal in mice
HE staining, ELISA, and immunohistochemistry were used to evaluate pathological changes and the degree Authors Juan Song , Miao Li , Cuicui Chen , Jian Zhou , Linlin Wang , Yu Yan , Jun She , Lin Tong , Yuanlin
- Ep 14 with Dr. Bryan Roth
Louis University in 1983, he subsequently trained in pharmacology (NIH), molecular biology, and psychiatry attending the lecture of a visiting professor on neurotransmission while in college in Montana, where he He was determined to work on psychiatric disorders and persevered even when he was told several times he would never make it as a basic scientist and would never publish anything important.
- Ep 27 with Dr. Robert J. Lefkowitz
., 2012 Nobel Prize in Chemistry, which he shared with Dr. Brian Kobilka . Before we pressed record, I asked if I could call him Bob, and he answered that only his mom used to then pressed record, and we chatted for almost 2h about Bob’s career, discoveries, difficulties (yes, he ’s had some too), Nobel week, and his memoir that he just published in collaboration with Dr. His legacy lies in the numerous discoveries he and his team made in the GPCR field and in all those who
- Ep 93 with Dr. Sri Kosuri
He is passionate about developing more rational ways to understand and engineer biology. Sri previously worked at the Wyss Institute and Harvard, where he built numerous technologies in gene He helped build Gen9, a gene synthesis company, as a member of the SAB and was the first employee of He is a Searle Scholar (2015), NIH New Innovator (2014), and received his ScD in Biological Engineering He enjoys eating, getting outdoors, and traveling with his wife and two children. Dr.
- Ep 110 with Dr. G. Aditya Kumar
He received his Ph.D. from the Centre for Cellular and Molecular Biology at Hyderabad, India, where he In addition, he explored the role of the host membrane in the entry of intracellular pathogens into macrophages He currently uses high-resolution fluorescence microscopy and biochemistry to study GPCR trafficking
- Illuminating Functional Selectivity and Allosterism at GPCRs.
He is also an Associate Leader of the Experimental Therapeutics and Metabolism Program and the Director He is a member of the Executive Committee of the Réseau québécois de recherche sur les médicaments. He has received many awards, including a Canada Research Chair, FRSQ scholarships and the CDA/CSEM/Merck He has developed innovative methods for in-cellulo measurement of protein-protein interactions, receptor He has contributed to the generation of many intellectual property agreements and patents, and published
- Ep 104 with Dr. Raul Gainetdinov
From 2013-2018, he was also a Professor at the Skolkovo Institute of Science and Technology (Skoltech Before joining the Department of Cell Biology in 1996 as a postdoc and becoming faculty at Duke in 2000, he He received a Ph.D. in pharmacology in 1992 from the Russian Academy of Medical Sciences and an M.D. Since 2013, he has been elected Chair of the subcommittee for the Dopamine receptors of the International As of August 2022, he has over 270 publications in scientific journals (including Science, Nature, Cell
- Ep 78 with Dr. Stuart Maudsley
At the end of his studies, he was awarded the Pfizer Prize for undergraduate research. He then completed his Ph.D. at Leeds as well as the University’s Ackroyd, Brotherton, and Brown Scholar Following this tremendous experience, he was recruited to be the Principal Investigator of the Receptor At the MRC he developed novel prostate cancer therapeutics based upon his research into GPCR pluridimensional At the NIH he was the recipient of the coveted NIH ‘Bench-to-Bedside’ Translational Research Grant Award
- Ep 37 with Dr. Samuel Hoare
He then moved to the National Institute of Mental Health, researching pharmacological mechanisms of Class As an industry pharmacologist, he consults with numerous pharma and biotechs in understanding and applying He specializes in kinetic analysis of drug action and is known for applying binding kinetics to the development He guided the in vitro biology efforts of the company for numerous drug discovery campaigns.
- Activation of orphan receptor GPR132 induces cell differentiation in acute myeloid leukemia
Authors Chunyang Yi, Jiacheng He, Dan Huang, Yumiao Zhao, Chan Zhang, Xiyun Ye, Ying Huang, Ruth Nussinov
- Ep 145 with Dr John Janetzko
He participated in various academic competitions, including math, physics, and chemistry contests. John explained that he was drawn to chemistry because it allowed him to build things in his mind and John also mentioned his university application process, which was less stressful than the US system. He then moved to Dan's lab where he met Suzanne and her project. He chose Brian's lab due to his interest in studying conformational changes.
- Advanced data analysis for GPCR pharmacology | Dr. GPCR Ecosystem
He consults with numerous pharmaceutical, biotech, life science and academic organizations in understanding He regularly teaches courses and publishes chapters and guides on basic and advanced pharmacology and He worked as a pharmacology leader in the pharmaceutical industry for 15 years at Neurocrine Biosciences He completed his Ph.D. in biochemistry, studying allosteric modulation of dopamine receptors, from the He completed postdoctoral training at the National Institute of Mental Health, researching the pharmacological
- Inhibition of Relaxin Autocrine Signaling Confers Therapeutic Vulnerability in Ovarian Cancer
Rottapel is a Senior Scientist at the Princess Margaret Cancer Centre where he holds the Amgen Chair He is a Professor in the Departments of Medicine, Immunology and Medical Biophysics at the University After completing his medical studies at George Washington University, the NIH and UCLA, he pursued his He has focussed on developing a comprehensive map of ovarian cancer essential genes using whole genome
- Ep 106 with Dr. Bruno Giros
at the Pierre and Marie Curie University in Paris and a short internship at Genentech Inc. in South San Schwartz in Paris, where he cloned and characterized dopamine D2 and D3 receptor subtypes. From 91 to 94, he was an assistant professor at Duke University in North Carolina, working with Marc Since 2008, he has arrived at McGill University as a Canada Research Chair. Giros has published more than 200 publications with an H factor of 79 and 32,000 citations (Google Scholar
- Ep 148 with Dr Arthur Christopoulos
He has received substantial, long-term support from international and national competitive, charitable He has also been the recipient of multiple awards, including the John J. In 2017, he was elected a Fellow of the Australian Academy of Health and Medical Sciences, in 2018 as a Fellow of the British Pharmacological Society, and in 2021 he was elected a Fellow of the Australian In 2023, he was elected a Fellow of the Pharmaceutical Society of Australia. " Dr.
- Ep 152 with Dr Arthur Christopoulos
He has received substantial, long-term support from international and national competitive, charitable He has also been the recipient of multiple awards, including the John J. In 2017, he was elected a Fellow of the Australian Academy of Health and Medical Sciences, in 2018 as a Fellow of the British Pharmacological Society, and in 2021 he was elected a Fellow of the Australian In 2023, he was elected a Fellow of the Pharmaceutical Society of Australia. " Dr.
- Ep 77 with Martin Audet
He is the head of the AudetLab located at the Institute of Pharmacology of Sherbrooke and is an emerging Michel Bouvier at Université de Montréal, followed by a Postdoctoral Fellow at Scripps Research in San
- Ep 55 with Mark Schmeizl
He has successfully built numerous global life science, leadership teams, & works closely with both clients
- Regulator of G protein signaling 16 restrains apoptosis in colorectal cancer through disrupting TRAF6-TAB2-TAK1-JNK/p38 MAPK signaling
Authors Hao Shen, Jie Yuan, Dafeng Tong, Bingchen Chen, Enda Yu, Guanglei Chen, Cheng Peng, Wenjun Chang
- Ep 120 with Brendan Wilkins
Since then, Brendan worked as a research assistant at the Victor Chang Cardiac Research Institute where he
- RGS5 maintaining vascular homeostasis is altered by the tumor microenvironment
Authors Peng Kong , Xu Wang , Ya-Kun Gao , Dan-Dan Zhang , Xiao-Fu Huang , Yu Song , Wen-Di Zhang , Rui-Juan Guo , Han Li , Mei Han Tags Breast cancer , Regulator of G protein signaling 5 , Vascular remodeling