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Shane Wright, Michel Bouvier, et al., for their work on Conformation- and activation-based BRET sensors

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June 2022 "Ottawa, Canada, May 10, 2022 — Orion Biotechnology Canada Ltd, a drug discovery and development company unlocking the therapeutic potential of G Protein-Coupled Receptors (GPCRs), today announced that it will be presenting important new data at both LSX World Congress and TIDES USA 2022 conference, taking place this week – May 10-12, 2022. Dr. Oliver Hartley, Orion’s Vice-President Drug Discovery, will present Orion’s novel technology for targeting undrugged peptidergic GPCRs. His presentations will describe Orion’s drug discovery platform, one of the fastest drug discovery solutions in the industry for targeting peptidergic GPCRs. Dr. Hartley will also present new data on Orion’s CCR2 antagonist, OB-004, demonstrating the ability of this powerful platform to rapidly identify best-in-class GPCR drug candidates." Read more at the source #DrGPCR #GPCR #IndustryNews

Latrophilin-1 drives neuron morphogenesis and shapes chemo- and mechanosensation-dependent behavior in

If you need a plasmid for your research or you want to share your materials, this is the place to go.

Choosing the Right Lab The lab you choose plays a pivotal role in shaping your PhD journey. However, with multiple great options, choosing the right lab wasn't easy. The right environment, paired with a supportive supervisor, laid the foundation for a fulfilling and The Role of Mentors and Supervisors Having the right mentor is indispensable for a successful PhD journey Supervisors not only guide your research but also shape your academic and professional growth.

Kevin Wright on his new position as Director of Targeted and Immuno-oncology at GPCR Therapeutics, our Kevin Wright Joins GPCR Therapeutics as Director of Targeted and Immuno-oncology Sosei Heptares Adds

Thomas Südhof, but did not start working on them right away. AB: The next workshop will likely bring together some of the hottest adhesion GPCR research going on right Day of the Dead celebrations: This happens over the weekend during the end of October and takes the shape The meat on a rotating spit with its bright red/orange chili-based marinade (spicy but not hot) catches

Ready for your GPCR quest, so bold and bright? Join us now, and let's explore with all our might! Let's make your brand shine like never before! in Neuroscience Ventral tegmental area amylin / calcitonin receptor signaling suppresses feeding and weight

In addition to its function about weight gain and appetite control mechanisms of MC3R, recent studies aimed to point out the importance of the MC3R regulations in three main concepts: 1) its impact on weight

Thank you for sharing your perspective and helping us shape the future of the Dr. GPCR ecosystem! accidental discoveries could revolutionise women’s health Seven unanswered questions about blockbuster weight-loss

Due to increasing numbers of people with excess body weight, the MC4R has become a target of interest setmelanotide, a novel synthetic MC4R agonist, suggest a predominant role of the Gq/11 pathway regarding weight

knock down SK and SKR reduced the transcription levels of the target genes and increased their body weight In parallel, injection of SK caused a significant reduction in body weight and increase in mortality

The reserved indications, where Addex retains exclusive rights to develop its own independent GABAB PAM program, have also been expanded to include chronic cough, in addition to the rights to develop certain

and, in this review, we have compared expression of GPCR mRNAs in human islets obtained from normal weight range donors, and those with a weight range classified as obese.

We are bursting with pride in sharing it with you, and we sincerely want to thank you for your support That's right, all the tidbits below will be for Premium Members ' eyes only. Septerna Touches New High, To Report SEP-786 Data In Mid-2025 How GPCR agonists, including antibodies, are shaping

The differentially expressed genes (DEGs) and weighted correlation network analysis (WGCNA) were performed

Moreover, independent of glucose control or weight loss, the anti-inflammatory actions of GLP-1RAs require

strategy is the so-called metabolic surgery whose beneficial effects are beyond dietary restrictions and weight

As we approach the event, we have some news to share: We’ve decided to make this event a trainee day Industry News Data shows nearly 19% weight loss in people with overweight or obesity in Boehringer Ingelheim

Bright illumination triggered Gαt1 translocation from the rod outer to inner segments in all three transgenic

If you want to share your work with our community, please don’t hesitate to fill out this form. You'll share your contributor articles with the community, stay updated with GPCR literature, join a Fragment-Based Design, Synthesis, and Characterization of Aminoisoindole-Derived Furin Inhibitors A Bright

That's right, you're about to level up your knowledge game! keep you on your toes  Direct line to all the cool cats in the GPCR community - Networking is key, right

Chemokines are low molecular weight proteins that their functional activities are achieved by binding

Heptares to receive US$2.5 million milestone payment from Formosa Pharmaceuticals Are GLP-1s finding the right

., Semaglutide vs Tirzepatide for Weight Loss in Adults With Overweight or Obesity.  

Bioscience Announces Site Relocation AI can help to speed up drug discovery — but only if we give it the right

More details will be shared soon, and registration will open in July 2024. Dr. GPCR Event Highlight We are thrilled to share the news of our in-person event in partnership with the binding genes unveiled via RNA polymerase II degradation Growth factor-dependent phosphorylation of Gαi shapes