Search Results
47 items found for "Siobán B Keel"
- Phase 1/2 study of sorafenib added to cladribine, high-dose cytarabine, G-CSF, and mitoxantrone in untreated AML
Authors Anna B Halpern , Eduardo Rodríguez-Arbolí , Megan Othus , Kelsey-Leigh A Garcia , Mary-Elizabeth Cassaday , Vivian G Oehler , Pamela S Becker , Jacob S Appelbaum , Janis L Abkowitz , Johnnie J Orozco , Siobán B Keel , Paul C Hendrie , Bart L Scott , M Cristina Ghiuzeli , Elihu H Estey , Roland B Walter Source
- Respiratory infections predominate after day 100 following B-cell maturation antigen-directed CAR T-cell therapy
News < GPCRs in Oncology and Immunology Respiratory infections predominate after day 100 following B-cell therapy Published date September 26, 2023 Abstract "Infections are an important complication after B-cell
- Combinatorial depletions of G-protein coupled receptor kinases in immune cells identify pleiotropic and cell type-specific functions
studies comparing the role of this GRK interplay for (a) multiple GPCRs within one leukocyte type, and (b) , combinatorial and complete GRK knockouts in four primary immune cell types (neutrophils, T cells, B Combined depletion of GRK2 and GRK6 in T cells and B cells shows distinct functional outcomes for (a) one GPCR type in different cell types, and (b) different GPCRs in one cell type. Authors Katharina M Glaser, Teresa K Tarrant, Tim Lämmermann Tags B cells; G-protein coupled receptors
- Chemoattractant receptor signaling in humoral immunity
2024 Abstract "Efficient induction of humoral immune responses depends on orchestrated migration of B recruits a specific GRK to chemoattractant receptors and plays an important role in the control of B Authors Taiichiro Shirai , Akiko Nakai , Kazuhiro Suzuki Tags B cell migration , COMMD3/8 complex , GRK
- Ep 30 with Dr. Elva Zhao
Her current research focuses on class B GPCRs and understanding how GPCR signaling and function is mediated Join me to learn more about Elva, class B GPCRs, and Tilly. Dr.
- Ep 26 with Dr. Debbie Hay
Her work is primarily focused on class B GPCRs and their interactions with RAMPs.
- Ep 44 with Dr. Steven Foord
These included the identification of RAMPs (solving some CGRP family issues) and the GABA B, carboxylic
- Comparison of infectious complications with BCMA-directed therapies in multiple myeloma
complications with BCMA-directed therapies in multiple myeloma Published date May 31, 2024 Abstract "B-cell-maturation-antigen Almeida Costa, Noriko Nishimura, Tasmin Farzana, Colin Rueda, David J Chung, Heather J Landau, Oscar B
- Ep 28 with Dr. Ross Cheloha
chatted about his work and transition to an independent investigator; join me to learn more about class B
- Ep 101 with Dr Caron Tribute Part 2
University School of Medicine in 1975 and then returned to join Duke’s faculty, where he remained as a James B. Neel Freedman (1994) Dr. Jacob Jacobson (2003) Dr. Stephane Laporte (1999) Dr.
- Ep 37 with Dr. Samuel Hoare
then moved to the National Institute of Mental Health, researching pharmacological mechanisms of Class B
- Ep 100 with Dr Caron Tribute Part 1
University School of Medicine in 1975 and then returned to join Duke’s faculty, where he remained as a James B.
- G protein coupled receptor transcripts in human immune cells and platelets
We have used the method to profile GPCR transcripts in white blood cells (WBCs)-B, CD4, CD8, NK, and
- Ep 27 with Dr. Robert J. Lefkowitz
Bob is James B.
- Ep 102 with Dr Caron Tribute Part 3
University School of Medicine in 1975 and then returned to join Duke’s faculty, where he remained as a James B.
- Chemokine Physiology in Cancer
Authors Donovan Drouillard, Brian T Craig, Michael B Dwinell Tags Chemokine receptor; cell migration;
- CCL5-producing migratory dendritic cells guide CCR5+ monocytes into the draining lymph nodes
Authors Kavita Rawat , Anita Tewari , Xin Li , Arlind B Mara , William T King , Sophie L Gibbings , Chinaza
- Observational Study of Repeat Immunoadsorption (RIA) in Post-COVID ME/CFS Patients with Elevated ß2-Adrenergic Receptor Autoantibodies-An Interim Report
for a randomised controlled trial (RCT), including sham apheresis, and for an RCT combining IA with B-cell
- Pan-cancer functional analysis of somatic mutations in G protein-coupled receptors
Authors Bongers B J , Gorostiola González M , Wang X , van Vlijmen HWT , Jespers W , Gutiérrez-de-Terán
- Ep 106 with Dr. Bruno Giros
Heinz Lehmann Award from the Canadian College of NeuroPsychopharmacology and the distinguished James B.
- Delivery of US28 by incoming HCMV particles rapidly attenuates Akt activity to suppress HCMV lytic replication in monocytes
Mahmud, Brittany W Geiler, Juthi Biswas, Michael J Miller, Julia E Myers, Stephen M Matthews, Amanda B
- Deletion of macrophage Gpr101 disrupts their phenotype and function dysregulating host immune responses in sterile and infectious inflammation
Authors Magdalena B Flak , Duco S Koenis , Maria Gonzalez-Nunez , Ana Chopo-Pizarro , Jesmond Dalli Tags
- Severity of neurological long-COVID symptoms correlates with increased level of autoantibodies targeting vasoregulatory and autonomic nervous system receptors
ARB1 and ARB2 correlated negatively CERAD Trail Marking A and B (R ≤ -0.26, p ≤ 0.043), while CHRM3 correlated
- S1P Signaling Genes as Prominent Drivers of BCR-ABL1-Independent Imatinib Resistance and Six Herbal Compounds as Potential Drugs for Chronic Myeloid Leukemia
six herbal compounds-ampelopsin, ellagic acid, colchicine, epigallocatechin-3-gallate, cucurbitacin B,
- Advanced data analysis for GPCR pharmacology | Dr. GPCR Ecosystem
training at the National Institute of Mental Health, researching the pharmacological mechanisms of Class B
- Characterization, expressional and evolutionary analysis of five fish-specific CCRs (CCR4La, CCR4Lc, CCR12a1, CCR12a2, and CCR12b) in largemouth bass (Micropterus salmoides)
largemouth bass CCR4La/Lc, and CCL5, CCL8, CCL7, CCL13 and CCL26 might be that of largemouth bass CCR12a1/a2/b.
- Comparative Analysis of the GNAI Family Genes in Glioblastoma through Transcriptomics and Single-Cell Technologies
regulation of actin cytoskeleton organization by the kinase effectors of Rho GTPases" and "Immune response B
- The β2-adrenergic receptor associates with CXCR4 multimers in human cancer cells
receptors (GPCR) dimers is well established, there is still a lack of consensus regarding class A and B