Stephen Ferguson About Dr. Stephen Ferguson Dr. Stephen Ferguson is a Professor in the Department of Cellular and Molecular Medicine at the University Marc G. receptor kinases and beta-arrestin in regulating G protein-coupled receptor endocytosis, trafficking Stephen Ferguson on the web Carlton University Canada Research Chairs Twitter ResearchGate LinkedIn Dr

Stephen Ferguson’s laboratory in the Departments of Cellular & Molecular Medicine and Neuroscience at the University of Ottawa as a Postdoctoral Fellow to explore novel G protein-coupled receptor (GPCR)

Stephen Ferguson’s laboratory in the Departments of Cellular & Molecular Medicine and Neuroscience at the University of Ottawa as a Postdoctoral Fellow to explore novel G protein-coupled receptor (GPCR)

and Immunology Functional Assessment of Cancer-Linked Mutations in Sensitive Regions of Regulators of G Three-Dimensional Missense Tolerance Ratio Analysis Published date January 1, 2023 Abstract Regulators of G regulators of G proteins. activation, G α binding properties, and downstream cAMP levels. Carolina Montañez-Miranda , Riley E Perszyk , Nicholas H Harbin , Jennifer Okalova , Suneela Ramineni , Stephen

Stephen Ferguson’s laboratory in the Departments of Cellular & Molecular Medicine and Neuroscience at the University of Ottawa as a Postdoctoral Fellow to explore novel G protein-coupled receptor (GPCR) Sakmar’s laboratory at The Rockefeller University, where she study’s the signaling and degradation of G

G. Aditya Kumar About Dr. G. Aditya Kumar Dr. G.

proteins by G protein-coupled receptors (GPCRs). for agonist-mediated activation of G proteins. changes in G protein structure. forms, specifically the short and long forms of the stimulatory G protein, Galpha-s(s) and Galpha-s( We demonstrated that Galpha-s(l), but not Galpha-s(s), regulates extracellularly regulated kinases (ERK

GPCR News < GPCRs in Oncology and Immunology Small-molecule targeting of GPCR-independent noncanonical G-protein signaling in cancer Published date April 25, 2023 Abstract " Activation of heterotrimeric G-proteins (Gαβγ) by G-protein-coupled receptors (GPCRs) is a quintessential mechanism of cell signaling widely However, it has become evident that heterotrimeric G-proteins can also be activated via GPCR-independent Tags G protein , GPCR , cancer , drug discovery .

< GPCR News < GPCRs in Oncology and Immunology Interplay between G protein-coupled receptors and nanotechnology Published date July 28, 2023 Abstract "G protein-coupled receptors (GPCRs), as the largest family of Wu , Rujing Wang , Mengnan Zhao , Canquan Mao , Sanjun Shi Tags Drug delivery , Endosomal delivery , G

< GPCR News < GPCRs in Oncology and Immunology G protein-coupled receptor-mediated signaling of immunomodulation in tumor progression Published date July 31, 2024 Abstract "G protein-coupled receptors (GPCRs) are

< GPCR News < GPCRs in Oncology and Immunology G protein coupled receptor transcripts in human immune cells and platelets Published date September 27, 2024 Abstract "G-protein coupled receptors (GPCRs)

Stephen Ferguson’s supervision.

Agenda Session II AGPCR signaling pathways and trafficking Localization of putative ligands for adhesion G Erwin G. Stephen, Caron Kathleen M Department of Cell Biology and Physiology at UNC Chapel Hill 111 Mason Farm Erwin G. Erwin G.

US28 is a virally encoded G protein-coupled receptor (GPCR) that is essential for silent infections within Authors Jamil Mahmud, Brittany W Geiler, Juthi Biswas, Michael J Miller, Julia E Myers, Stephen M Matthews

GPCR News < GPCRs in Oncology and Immunology Pan-cancer functional analysis of somatic mutations in G protein-coupled receptors Published date December 1, 2022 Abstract G Protein-coupled receptors (GPCRs

< GPCR News < GPCRs in Oncology and Immunology Signaling by Neutrophil G Protein-Coupled Receptors that Neutrophils, which express many receptors that are members of the large family of G protein-coupled receptors

Harrington Discovery Institute and Case Western Reserve University, where he studies GPCR regulation by S-nitrosylation For this, we have worked in three main areas: the regulation of G protein-coupled receptor signaling particularly by the G protein-coupled receptor kinase (GRK) – beta-arrestin system, the coordination of heterotrimeric G protein, small GTP-binding protein and protein kinase pathways by GIT/PIX scaffolding complexes during cellular signaling, and characterizing the role of protein S-nitrosylation as a signaling

Harrington Discovery Institute and Case Western Reserve University, where he studies GPCR regulation by S-nitrosylation For this, we have worked in three main areas: the regulation of G protein-coupled receptor signaling particularly by the G protein-coupled receptor kinase (GRK) – beta-arrestin system, the coordination of heterotrimeric G protein, small GTP-binding protein and protein kinase pathways by GIT/PIX scaffolding complexes during cellular signaling, and characterizing the role of protein S-nitrosylation as a signaling

Harrington Discovery Institute and Case Western Reserve University, where he studies GPCR regulation by S-nitrosylation For this, we have worked in three main areas: the regulation of G protein-coupled receptor signaling particularly by the G protein-coupled receptor kinase (GRK) – beta-arrestin system, the coordination of heterotrimeric G protein, small GTP-binding protein and protein kinase pathways by GIT/PIX scaffolding complexes during cellular signaling, and characterizing the role of protein S-nitrosylation as a signaling

Harrington Discovery Institute and Case Western Reserve University, where he studies GPCR regulation by S-nitrosylation For this, we have worked in three main areas: the regulation of G protein-coupled receptor signaling particularly by the G protein-coupled receptor kinase (GRK) – beta-arrestin system, the coordination of heterotrimeric G protein, small GTP-binding protein and protein kinase pathways by GIT/PIX scaffolding complexes during cellular signaling, and characterizing the role of protein S-nitrosylation as a signaling

< GPCR News < GPCRs in Oncology and Immunology Combinatorial depletions of G-protein coupled receptor cells identify pleiotropic and cell type-specific functions Published date November 1, 2022 Abstract G-protein They can be recruited to agonist-activated G-protein coupled receptors (GPCRs) and phosphorylate their Authors Katharina M Glaser, Teresa K Tarrant, Tim Lämmermann Tags B cells; G-protein coupled receptors

< GPCR News < GPCRs in Oncology and Immunology The orphan G protein-coupled receptor 141 expressed in myeloid cells functions as an inflammation suppressor Published date April 29, 2024 Abstract "G protein-coupled Authors Atsuya Sawabe, Shogo Okazaki, Akira Nakamura, Ryo Goitsuka, Tomonori Kaifu Tags G protein–coupled

< GPCR News < GPCRs in Oncology and Immunology Regulator of G protein signaling protein 6 alleviates Regulator of G protein signaling protein 6 (RGS6), identified as a tumor suppressor gene, has received Methods: Congruously regulated G protein-coupled receptor (GPCR)-related genes and differentially expressed Tong , Yuanlin Song Tags Acute lung injury , Apoptosis , Cell-renewal , Inflammation , Regulator of G

< GPCR News < GPCRs in Oncology and Immunology Regulator of G protein signaling 16 restrains apoptosis G protein signaling (RGS) protein family modulators play essential role within regulating downstream Our study focused on the expression patterns of RGS proteins in CRC, identifying Regulator of G protein

< GPCR News < GPCRs in Oncology and Immunology Identification of a G-protein coupled receptor-related G protein-coupled receptors (GPCRs, the largest family of human cell surface receptors) are associated Authors Shaohan Ma, Ruyue Li, Guangqi Li, Meng Wei, Bowei Li, Yongmei Li, Chunfang Ha Tags G protein-coupled

< GPCR News < GPCRs in Oncology and Immunology Gallein, G protein βγ subunits inhibitor, suppresses the carcinoma cells via inhibition of the c-Jun N-terminal kinase Published date November 13, 2024 Abstract "G protein-coupled receptor (GPCR) signaling regulates a wide range of pathophysiological cell functions via G

the nematode-trapping fungus, Arthrobotrys flagrans, that both are achieved through a dual-function G-protein-coupled revealed that ascarosides activate the fungal GPCR, GprC, at the plasma membrane and together with the G-protein Authors Xiaodi Hu, David S Hoffmann, Mai Wang, Lars Schuhmacher, Maria C Stroe, Birgit Schreckenberger

G-protein-coupled receptors (GPCRs) are the most intensively studied drug targets but are underexplored The Author(s), under exclusive licence to Springer Nature America, Inc." Authors Victoria H Wu , Bryan S Yung , Farhoud Faraji , Robert Saddawi-Konefka , Zhiyong Wang , Alexander T Wenzel , Miranda J Song , Meghana S Pagadala , Lauren M Clubb , Joshua Chiou , Sanju Sinha , Marin Matic , Francesco Raimondi , Thomas S Hoang , Rebecca Berdeaux , Dario A A Vignali , Ramiro Iglesias-Bartolome