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4 items found for "T2DM"
- Orphan receptor GPR50 attenuates inflammation and insulin signaling in 3T3-L1 preadipocytes
insulin signaling in 3T3-L1 preadipocytes Published date November 1, 2022 Abstract Type 2 diabetes (T2DM Although the mechanism of T2DM is not yet fully known, inflammation and insulin resistance play a central role in the pathogenesis of T2DM. GPR50 expression was observed to be significantly increased in the adipose tissue of obese T2DM mice,
- CB2 stimulation of adipose resident ILC2s orchestrates immune balance and ameliorates type 2 diabetes mellitus
2 diabetes mellitus Published date July 3, 2024 Abstract "Development of type 2 diabetes mellitus (T2DM vivo approaches to explore the functional and therapeutic impacts of CB2 engagement on VAT ILC2s in a T2DM The results reveal that the CB2 agonist can serve as a candidate for the prevention and treatment of T2DM Yoshihiro Sakano, Benjamin P Hurrell, Omid Akbari Tags CB2 , CP: Immunology , CP: Metabolism , ILC2 , T2DM
- Ep 62 with Dr. Sai Prasad Pydi
Pydi's laboratory is to develop GPCR-based drugs for the treatment of obesity and Type 2 Diabetes (T2D
- Ep 45 with Dr Ralf Jockers
MT2 variants are biased and their defects are signaling pathway-specific opening new perspectives for T2D