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August 2022 A new Kunitz-type snake toxin family associated with an original mode of interaction with the vasopressin 2 receptor "Abstract Background and purpose: Venomous animals express numerous Kunitz-type We aimed to exploit other mamba venoms to enlarge the V2R-Kunitz peptide family and gain insight into Sequence comparison between active and non-active V2R Kunitz peptides highlighted five positions, among Conclusions and implications: A new function and mode of action is associated with the Kunitz peptides

October 2022 Cholesterol-Dependent Dynamics of the Serotonin1A Receptor Utilizing Single Particle Tracking To explore the role of cholesterol in lateral dynamics of GPCRs, we utilized single particle tracking

We used TIRF microscopy and a statistical method to track and classify the motion of different receptor

GPCR Podcast << Back to podcast list Brian Shoichet About Dr. Brian Shoichet BSc in Chemistry from MIT, Ph.D. with Tack Kuntz at UCSF; Postdoc with Brian Matthews crystallography; started my independent lab at Northwestern University Medical School (1996) was recruited back

Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Download PDF Program HERE < Back to Full Agenda State of the Art Talk Adhesion GPCR in Mechanobiology Abstract Only Available for AGPCR24

< GPCR News < GPCRs in Oncology and Immunology From outside to inside and back again: the lysophosphatidic