Search Results
253 items found for "Tara L Lin"
- Spliceosome mutations are associated with clinical response in a phase 1b/2 study of the PLK1 inhibitor onvansertib in combination with decitabine in relapsed or refractory acute myeloid leukemia
Authors Peter J P Croucher , Maya Ridinger , Pamela S Becker , Tara L Lin , Sandra L Silberman , Eunice
- Cannabinoid compounds to augment L-DOPA treatment in Parkinson's Disease
Contest Committee Sponsors GPCR Retreat Program < Back to schedule Cannabinoid compounds to augment L-DOPA
- Neurotoxicity and accumulation of CPPD quinone at environmentally relevant concentrations in Caenorhabditis elegans
After exposure to 0.01-10 μg/L CPPDQ, obvious body accumulation of CPDDQ was detected. Meanwhile, exposure to CPPDQ (0.01-10 μg/L) decreased head thrash, body bend, and forward turn, and increased Nevertheless, only exposure to 10 μg/L CPPDQ induced neurodegeneration in GABAergic system. Exposure to CPPDQ (0.01-10 μg/L) further decreased expressions of daf-7 encoding TGF-β ligand, jnk-1 Additionally, among examined G protein-coupled receptor (GPCR) genes, exposure to CPPDQ (0.01-10 μg/L)
- [Inhibitory effect of downregulating G protein-coupled receptor class C group 5 member A expression on lipopolysaccharide-induced inflammatory response in human gingival fibroblasts]
GFs were isolated with enzymic digestion and transfected with 30, 50 and 80 μmol/L small interfering The mRNA and protein levels of GPRC5A in GFs under 1 mg/L LPS-induced GFs inflammatory state were evaluated The 50 μmol/L group displayed the most significant decrease in GPRC5A expression (31.16±3.29) compared Authors Y H Hu , L L Shang , S H Ge Source Contribute to the GPCR News Coming soon Become a Contributor
- Ep 107 with Dr. Roger Sunahara
forms, specifically the short and long forms of the stimulatory G protein, Galpha-s(s) and Galpha-s(l) We demonstrated that Galpha-s(l), but not Galpha-s(s), regulates extracellularly regulated kinases (ERK We speculate that these aberrations in Galpha-s(l), specifically, may be involved in other pathologies Roger Sunahara on the web UCSD Profile Google Scholar ResearchGate LinkedIn Dr.
- From odor to oncology: non-canonical odorant receptors in cancer
receptors, dysregulation of non-canonical odorant receptors such as trace amine-associated receptors (TAARs Authors Sung Jin Park , Paul L Greer , Namgyu Lee Source Contribute to the GPCR News Coming soon Become
- CCL5-producing migratory dendritic cells guide CCR5+ monocytes into the draining lymph nodes
Authors Kavita Rawat , Anita Tewari , Xin Li , Arlind B Mara , William T King , Sophie L Gibbings , Chinaza
- Phase 1/2 study of sorafenib added to cladribine, high-dose cytarabine, G-CSF, and mitoxantrone in untreated AML
Mary-Elizabeth M Percival , Ryan D Cassaday , Vivian G Oehler , Pamela S Becker , Jacob S Appelbaum , Janis L Abkowitz , Johnnie J Orozco , Siobán B Keel , Paul C Hendrie , Bart L Scott , M Cristina Ghiuzeli , Elihu
- LP2, a cyclic angiotensin-(1-7) analog extended with an N-terminal D-lysine, impairs growth of patient-derived xenografts of colorectal carcinoma in mice
xenografts of colorectal carcinoma in mice Published date February 1, 2023 Abstract " LP2 is a 4, 7 D, L warrant further evaluation of LP2's inhibitory potential of colorectal cancer. " Authors P Namsolleck , L
- Elucidation of active components and target mechanism in Jinqiancao granules for the treatment of prostatitis and benign prostatic hyperplasia
., Pyrrosia calvata (Baker) Ching, Plantago asiatica L. and stigma of Zea mays L. Nitric acid (NO) inhibition was tested on the macrophage cell line RAW264.7.
- Ep 105 with Annabelle Milner
In particular, she is looking at L- and D-lactate-activated HCAR1 signaling. Annabelle Milner on the web Linkedin Researchgate Pubmed Dr.
- Comparison of infectious complications with BCMA-directed therapies in multiple myeloma
Authors Karthik Nath, Tala Shekarkhand, David Nemirovsky, Andriy Derkach, Bruno Almeida Costa, Noriko Tasmin Farzana, Colin Rueda, David J Chung, Heather J Landau, Oscar B Lahoud, Michael Scordo, Gunjan L
- Student Flash Presentations | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Hsi-Hsien Lin as summer intern twice, and finally joined the lab of Prof. Engel. K, Murphy JM, Harvey CA, Dunlap S, Gehrs L, Lee H, Kim HG, Sah JP, Lee SN, Stanford D, Barrington RA Alex Torrelli-Diljohn on the web The University of Alabama at Birmingham LinkedIn GPR124 Mediates Adhesion Emmanouil Kyrloglou on the web Adhesion GPCR Consortium LinkedIn A single cell GPCR map of thermogenic Tyler Bernadyn on the web LinkedIn Next Generation MBD2 inhibitors for Brain Cancer Therapy Jesse Stillwell
- Dopamine-Mediated Motor Recovery after Ischemic Stroke
hope our research will aid in the development of new therapeutic interventions for the alleviation of L-DOPA-induced Mario Tiberi on the web University of Ottawa Pubmed Google Scholar ResearchGate LinkedIn Dr.
- GPR56: GPCR as a guardian against ferroptosis
Lin et al. demonstrated that GPR56, a G-protein-coupled receptor, can be activated by its agonist to
- Emerging GPCR targets for AUD: Insights from preclinical studies
Authors Roberta Goncalves Anversa, Maiya L Barron, Leigh C Walker, Andrew J Lawrence Source Contribute
- "Have a nice weekend, and I'll see you tomorrow!": RAMP-interacting GPCR Pathways
Caron, Ph.D. is the Frederik L. Kathleen Caron on the web UNC-Chapel Hill Department of Cell Biology and Physiology UNC Lineberger Comprehensive
- Ep 103 with Dr Kathleen Caron
Caron, Ph.D. is the Frederik L.
- Wnt pathway inhibition with the porcupine inhibitor LGK974 decreases trabecular bone but not fibrosis in a murine model with fibrotic bone
showed that ColI(2.3)+/Rs1+ mice, in which Gs-GPCR signaling was hyper-activated in osteoblastic cell lineages Authors Hsuan Lung, Kelly L Wentworth, Tania Moody, Ariane Zamarioli, Apsara Ram, Gauri Ganesh, Misun
- CaaX-motif-adjacent residues influence G protein gamma (Gγ) prenylation under suboptimal conditions
Prenyltransferases tether isoprenoid lipids to proteins via a thioether linkage during prenylation. Authors Mithila Tennakoon , Waruna Thotamune , John L Payton , Ajith Karunarathne Tags HMG-CoA reductase
- The binding mechanism of an anti-multiple myeloma antibody to the human GPRC5D homodimer
Authors Pengfei Yan, Xi Lin, Lijie Wu, Lu Xu, Fei Li, Junlin Liu, Fei Xu Source Contribute to the GPCR
- Identification of Small-Molecule Antagonists Targeting the Growth Hormone Releasing Hormone Receptor (GHRHR)
Papadourakis, Konstantinos Tsianakas, Robert P Millar, Ross C Anderson, Georgios A Spyroulias, Claire L
- Mutation Patterns Predict Drug Sensitivity in Acute Myeloid Leukemia
Authors Guangrong Qin, Jin Dai, Sylvia Chien, Timothy J Martins, Brenda Loera, Quy H Nguyen, Melanie L
- Stretch regulates alveologenesis and homeostasis via mesenchymal Gαq/11-mediated TGFβ2 activation
homeostasis. " Authors Amanda T Goodwin , Alison E John , Chitra Joseph , Anthony Habgood , Amanda L
- Ascitic Shear Stress Activates GPCRs and Downregulates Mucin 15 to Promote OvarianCancer Malignancy
Jackson, Ishwarya Venkata Narayanan, Fulei Wuchu, Minal Nenwani, Zachary Fischer, Alec Sunshine, Zequan Lin , Linh Tran, Deepak Nagrath, Mats Ljungman, Katherine Maturen, Analisa DiFeo, David Nordsletten Tags
- Single cell G-protein coupled receptor profiling of Transcription factor 21 expressing activated kidney fibroblasts
Kaur , Veera Ganesh Yerra , Sri Nagarjun Batchu , Duc Tin Tran , Md Golam Kabir , Youan Liu , Suzanne L
- G protein-coupled estrogen receptor (GPER)/GPR30 forms a complex with the β1-adrenergic receptor, a membrane-associated guanylate kinase (MAGUK) scaffold protein, and protein kinase A anchoring protein (AKAP) 5 in MCF7 breast cancer cells
Authors Julia Tutzauer , D Stephen Serafin , Tobias Schmidt , Björn Olde , Kathleen M Caron , L M Fredrik
- GPR97 depletion aggravates imiquimod-induced psoriasis pathogenesis via amplifying IL-23/IL-17 axis signal pathway
Authors Yaoxin Gao, Weirong Zhan, Dandan Guo, Haizhen Lin, Muhammad Asad Farooq, Chenxu Jin, Li Zhang