Search Results
63 items found for "Thomas S Hoang"
- The GPCR-Gαs-PKA signaling axis promotes T cell dysfunction and cancer immunotherapy failure
The Author(s), under exclusive licence to Springer Nature America, Inc." Authors Victoria H Wu , Bryan S Yung , Farhoud Faraji , Robert Saddawi-Konefka , Zhiyong Wang , Alexander T Wenzel , Miranda J Song , Meghana S Pagadala , Lauren M Clubb , Joshua Chiou , Sanju Sinha , Marin Matic , Francesco Raimondi , Thomas S Hoang , Rebecca Berdeaux , Dario A A Vignali , Ramiro Iglesias-Bartolome
- Ep 50 with Dr. Thomas P. Sakmar
Thomas P. Sakmar About Dr. Thomas P. dynamics simulations and coarse-grain sampling approaches for membrane proteins in collaborations with Thomas Thomas P.
- Ep 119 with Tanishka S. Saraf
GPCR Podcast << Back to podcast list Tanishka S. Saraf About Tanishka S. neurobiology of neuropsychiatric disorders and to develop safe and effective treatments. " Tanishka S.
- Ep 38 with Dr. Alexander S. Hauser
Alexander S. Hauser About Dr. Alexander S. Alexander S.
- Developing a PROTAC to Degrade the Constitutively Active Onco-GPCR in Uveal Melanoma
Thomas Sakmar’s laboratory at Rockefeller University, where she studies the signaling and degradation started her Ph.D. at the Tri-Institutional Ph.D. program in Chemical Biology, where she joined the lab of Thomas
- Ep 66 with Dr. Antony A. Boucard Jr
Thomas Südhof . Boucard´s lab focuses on molecular and cellular mechanisms underlying the function of adhesion GPCRs
- GPCR Retreat 2023 - Part II
Thomas Sakmar’s laboratory at The Rockefeller University, where she study’s the signaling and degradation started her Ph.D. at the Tri-Institutional Ph.D. program in Chemical Biology, where she joined the lab of Thomas
- Ep 56 with Dr. Adriano Marchese
He then moved to Thomas Jefferson University in Philadelphia, PA, for his postdoctoral training in Jeff
- Increased protease-activated receptor 1 autoantibodies are associated with severe COVID-19
Schinke , Nadja Käding , Jens Y Humrich , Otávio Cabral-Marques , Joana P Bernardes , Neha Mishra , Thomas
- Ep 18 with Dr. Yamina Berchiche
Oprea , Thomas Sakmar , Aurelien Rizk & Yaroslav Nikolaev .
- Using food perception and bioamine signaling networks to slow aging
Miller 1, Shijiao Huang 1, Elizabeth S. Dean 1, and Scott F. Leiser 1 1.
- Ep 42 with Dr. Randy Hall
to the Vollum Institute in Portland, Oregon, to do a post-doctoral fellowship in the laboratory of Thomas
- Respiratory infections predominate after day 100 following B-cell maturation antigen-directed CAR T-cell therapy
Authors Jessica S Little , Megha Tandon , Joseph Seungpyo Hong , Omar Nadeem , Adam S Sperling , Noopur
- CircFKBP5 Suppresses Apoptosis and Inflammation and Promotes Osteogenic Differentiation
differentiation of hDPSCs was investigated by performing alkaline phosphatase (ALP) staining and alizarin red S Authors Cuiwei Liang , Wenmiao Li , Qian Huang , Qitao Wen .
- Ep 107 with Dr. Roger Sunahara
G protein splice forms, specifically the short and long forms of the stimulatory G protein, Galpha-s( s) and Galpha-s(l), respectively. We demonstrated that Galpha-s(l), but not Galpha-s(s), regulates extracellularly regulated kinases (ERK We speculate that these aberrations in Galpha-s(l), specifically, may be involved in other pathologies
- Deciphering the genetic landscape of lumpy skin disease: Unraveling variable virulence through comprehensive genome sequence analysis in India
Authors R Mishra, S K Biswas, S Nandi, S Mahajan, K G Sai Balaji, V Gairola, D Poloju, S Gulzar, K P
- Blockade of vasoactive intestinal peptide receptor 2 (VIPR2) signaling suppresses cyclin D1-dependent cell-cycle progression in MCF-7 cells
The percentage of cells in the S-M phase was decreased in MCF-7 cells treated with KS-133. MEK) inhibitor U0126 and the class I PI3K inhibitor ZSTK474 decreased the percentage of cells in the S KS-133 reduced the percentage of cells in the S phase more than treatment with U0126 or ZSTK474 alone regulates cyclin D1 levels through the cAMP/PKA/ERK and PI3K/AKT/GSK3β pathways, and mediates the G1/S
- Stimulation of ectopically expressed muscarinic receptors induces IFN-γ but suppresses IL-2 production by inhibiting activation of pAKT pathways in primary T cells
Authors Trang T T Nguyen , Wen Lu , Wandi S Zhu , K Mark Ansel , Hong-Erh Liang , Arthur Weiss .
- GPR68-ATF4 signaling is a novel prosurvival pathway in glioblastoma activated by acidic extracellular microenvironment
Authors Charles H Williams , Leif R Neitzel , Jessica Cornell , Samantha Rea , Ian Mills , Maya S Silver Jovanni D Ahmad , Konstantin G Birukov , Anna Birukova , Henry Brem , Betty Tyler , Eli E Bar , Charles C Hong
- Phase 1/2 study of sorafenib added to cladribine, high-dose cytarabine, G-CSF, and mitoxantrone in untreated AML
Othus , Kelsey-Leigh A Garcia , Mary-Elizabeth M Percival , Ryan D Cassaday , Vivian G Oehler , Pamela S Becker , Jacob S Appelbaum , Janis L Abkowitz , Johnnie J Orozco , Siobán B Keel , Paul C Hendrie , Bart
- Ep 132 with Dr. Richard Premont
Harrington Discovery Institute and Case Western Reserve University, where he studies GPCR regulation by S-nitrosylation by GIT/PIX scaffolding complexes during cellular signaling, and characterizing the role of protein S-nitrosylation
- Ep 130 with Dr. Richard Premont
Harrington Discovery Institute and Case Western Reserve University, where he studies GPCR regulation by S-nitrosylation by GIT/PIX scaffolding complexes during cellular signaling, and characterizing the role of protein S-nitrosylation
- Ep 133 with Dr. Richard Premont
Harrington Discovery Institute and Case Western Reserve University, where he studies GPCR regulation by S-nitrosylation by GIT/PIX scaffolding complexes during cellular signaling, and characterizing the role of protein S-nitrosylation
- Ep 131 with Dr. Richard Premont
Harrington Discovery Institute and Case Western Reserve University, where he studies GPCR regulation by S-nitrosylation by GIT/PIX scaffolding complexes during cellular signaling, and characterizing the role of protein S-nitrosylation
- Proteogenomic landscape and clinical characterization of GH-producing pituitary adenomas/somatotroph pituitary neuroendocrine tumors
characteristics of growth hormone (GH)-producing pituitary adenomas/somatotroph pituitary neuroendocrine tumors (GHomas the genetic alterations, protein expression profiles, transcriptomes, and clinical characteristics of GHomas genes and nontargeted proteomics analysis were performed on fresh-frozen samples from 121 sporadic GHomas
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- Spliceosome mutations are associated with clinical response in a phase 1b/2 study of the PLK1 inhibitor onvansertib in combination with decitabine in relapsed or refractory acute myeloid leukemia
Authors Peter J P Croucher , Maya Ridinger , Pamela S Becker , Tara L Lin , Sandra L Silberman , Eunice S Wang , Amer M Zeidan Tags AML , Biomarker , Hypomethylating agents , Onvansertib , PLK1 , Splicing
- Ep 09 with Lauren Celano
GPCR podcast episode, we sat down to chat with Lauren Celano to talk about career options for Ph.D.’s.