., W. Ko, Z.Y. Weinberg, and M.A. Puthenveedu. 2021. Wickner, W., and R. Schekman. 2008. Membrane fusion. Nat. Struct. Mol. Biol. 15:658–664.

., Weis, W. I., & Kobilka, B. K. (2011). C., Gmeiner, P., Steyaert, J., Weis, W. I., Garcia, K. C., Wess, J., & Kobilka, B. K. (2013).

Nature 630, 493–500 (2024). https://doi.org/10.1038/s41586-024-07487-w

Earl W. Earl W. Earl W. Sir James W. Sir James W.

Thus, this finding raises the possibility that GPCR priming might result not only from intricate receptor-G Stallaert, W., et al., Purinergic Receptor Transactivation by the β(2)-Adrenergic Receptor Increases

Guo, W., et al., Crosstalk in G protein-coupled receptors: Changes at the transmembrane homodimer interface

W., & Skiniotis, G. (2023).

., Coyote-Maestas, W., & Aashish Manglik. (2024).

This week's highlight includes congrats to: Junyi Liang, Niña Caculitan, and Adam W Smith for their research

For example, OR4M1 was proposed to interfere with aberrant tau hyperphosphorylation (Zhao W. et. al 2013

development of biased ligands, which promote the engagement of the receptor with a certain effector, thus therapeutic applications are situated in the area of chronic inflammatory disease (Proudfoot, Power, and Schwarz

Thus, exploring large-scale protein-protein interaction datasets could shed light on connections between their imbalance is linked to pathological conditions, including cancer (Gros, R. et al. 2000, Sun, W.