August 2022 A NanoBRET-Based H 3 R Conformational Biosensor to Study Real-Time H 3 Receptor Pharmacology

This year Arum Wu et al. reported a library of Nbs to study the allosteric modulation of the rhodopsin H., Pautsch, A., Steyaert, J., Weis, W. I., & Kobilka, B. K. (2011). M., Manglik, A., Hu, J., Hu, K., Eitel, K., Hübner, H., Pardon, E., Valant, C., Sexton, P. O., Ploegh, H. L., & Garcia, K. C. (2015). Structural biology. Science (New York, N.Y.), 347(6226), 1113–1117. https://doi.org/10.1126/science.aaa5026 Wu, A., Salom

peroxidase enzyme that catalyzes the oxidation of specific substrates in the presence of hydrogen peroxide (H When AUR is oxidized by APEX2 in the presence of H 2 O 2 , it produces a fluorescent product that can

Authors Victoria H Wu , Bryan S Yung , Farhoud Faraji , Robert Saddawi-Konefka , Zhiyong Wang , Alexander

Constitutively Active Onco-GPCR in Uveal Melanoma Date & Time Friday, November 3rd / 4:20 PM About Victoria Rasmussen "Victoria Rasmussen is a graduate fellow in Dr. Victoria started her Ph.D. at the Tri-Institutional Ph.D. program in Chemical Biology, where she joined states to help test the feasibility of using protein-targeted degradation as a therapeutic strategy. " Victoria

RT-qPCR results showed that the gene expression levels of GPRC5A at different time point (2, 6, 12, 24 h) group (0.004±0.000, 0.004±0.000, 0.002±0.000, 0.007±0.000) (all P<0.001), respectively, and peaked at 6 h. Authors Y H Hu , L L Shang , S H Ge Source Contribute to the GPCR News Coming soon Become a Contributor