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10 items found for "Virulence"
- Molecular docking and dynamics simulation studies uncover the host-pathogen protein-protein interactions in Penaeus vannamei and Vibrio parahaemolyticus
between several immune-related proteins of P. vannamei with V. parahaemolyticus proteins associated with virulence
- Delivery of US28 by incoming HCMV particles rapidly attenuates Akt activity to suppress HCMV lytic replication in monocytes
US28 is a virally encoded G protein-coupled receptor (GPCR) that is essential for silent infections within We found that preformed US28 was rapidly delivered to monocytes by HCMV viral particles, whereas the A recombinant mutant virus lacking US28 (US28Δ) was unable to establish a quiescent infection, resulting in a fully productive lytic infection able to produce progeny virus. kinase Akt at Ser473 and Thr308, in contrast with the phosphorylation of Akt only at Ser473 after WT viral
- The EBI2 receptor is coexpressed with CCR5 in CD4+ T cells and boosts HIV-1 R5 replication
HIV-1 entry was quantified with virions harboring β-lactamase fused to the viral protein vpr, early and late HIV-1 transcriptions by qPCR, NFkB nuclear activation by immunofluorescence and transfection, and viral We observed that this coexpression reduced viral entry by 50%. It might be of interest to test the effect of EBI2 antagonists on the residual viral production persisting
- Ep 126 with Dr. Françoise Bachelerie
FB leads a team at Paris-Saclay University with expertise in immunology and virology related to Host/Virus the ligand for the CXCR4 receptor and can therefore prevent infection by the Human Immunodeficiency Virus
- A virally encoded GPCR drives glioblastoma through feed-forward activation of the SK1-S1P1 signaling axis
< GPCR News < GPCRs in Oncology and Immunology A virally encoded GPCR drives glioblastoma through feed-forward
- Ep 48 with Dr Nyla Naim Dr Michael Lemieux Dr Jason Nasse from Addgene
Jason Nasse is a senior scientist at Addgene specializing in the use of AAV viral vectors.
- Ep 53 with Dr. Timo De Groof
nanobody platform within the research group and used this platform to develop nanobodies targeting viral
- GPCR Retreat 2023 - Part II
Richard Vile's lab at Mayo Clinic where she aided the evaluation of tumor-specific oncolytic viruses.
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