Search Results
112 items found for "Vivian G Oehler"
- Ep 110 with Dr. G. Aditya Kumar
G. Aditya Kumar About Dr. G. Aditya Kumar Dr. G.
- G Proteins and GPCRs in Cancer: Novel Precision Targeted and Immunotherapies
About Program Registration Logo Contest Committee Sponsors GPCR Retreat Program < Back to schedule G His research team has pioneered the study of G proteins and G protein coupled receptors (GPCRs) in human
- G protein-coupled receptor-mediated signaling of immunomodulation in tumor progression
< GPCR News < GPCRs in Oncology and Immunology G protein-coupled receptor-mediated signaling of immunomodulation in tumor progression Published date July 31, 2024 Abstract "G protein-coupled receptors (GPCRs) are
- Functional Assessment of Cancer-Linked Mutations in Sensitive Regions of Regulators of G Protein Signaling Predicted by Three-Dimensional Missense Tolerance Ratio Analysis
and Immunology Functional Assessment of Cancer-Linked Mutations in Sensitive Regions of Regulators of G Three-Dimensional Missense Tolerance Ratio Analysis Published date January 1, 2023 Abstract Regulators of G protein signaling (RGS) proteins modulate G protein-coupled receptor (GPCR) signaling by acting as negative regulators of G proteins. activation, G α binding properties, and downstream cAMP levels.
- G Protein-coupled Receptor-mediated Membrane Targeting of PLCγ2 is Essential for Neutrophil Chemotaxis
< GPCR News < GPCRs in Oncology and Immunology G Protein-coupled Receptor-mediated Membrane Targeting Neutrophil Chemotaxis Published date April 11, 2023 Abstract " The current dogma is that chemoattractants G Tags G protein-coupled receptor (GPCR) , calcium-promoted Ras inactivator (CAPRI) , chemotaxis , neutrophils
- Signaling by Neutrophil G Protein-Coupled Receptors that Regulate the Release of Superoxide Anions
< GPCR News < GPCRs in Oncology and Immunology Signaling by Neutrophil G Protein-Coupled Receptors that Neutrophils, which express many receptors that are members of the large family of G protein-coupled receptors
- G protein-coupled receptors: A target for microbial metabolites and a mechanistic link to microbiome-immune-brain interactions
< GPCR News < GPCRs in Oncology and Immunology G protein-coupled receptors: A target for microbial metabolites studies have demonstrated that small-molecules from gut microbiota act as ligands for specific human G Authors Gajender Aleti , Emily A Troyer , Suzi Hong Tags G protein-coupled receptors , Gut microbiota
- CaaX-motif-adjacent residues influence G protein gamma (Gγ) prenylation under suboptimal conditions
< GPCR News < GPCRs in Oncology and Immunology CaaX-motif-adjacent residues influence G protein gamma Building on our previous finding that statins inhibit membrane association of G protein γ (Gγ) in a subtype-dependent findings indicate a plausible mechanism allowing for statins to differentially perturb heterotrimeric G
- The orphan G protein-coupled receptor 141 expressed in myeloid cells functions as an inflammation suppressor
< GPCR News < GPCRs in Oncology and Immunology The orphan G protein-coupled receptor 141 expressed in myeloid cells functions as an inflammation suppressor Published date April 29, 2024 Abstract "G protein-coupled Authors Atsuya Sawabe, Shogo Okazaki, Akira Nakamura, Ryo Goitsuka, Tomonori Kaifu Tags G protein–coupled
- Regulator of G protein signaling 16 restrains apoptosis in colorectal cancer through disrupting TRAF6-TAB2-TAK1-JNK/p38 MAPK signaling
< GPCR News < GPCRs in Oncology and Immunology Regulator of G protein signaling 16 restrains apoptosis G protein signaling (RGS) protein family modulators play essential role within regulating downstream Our study focused on the expression patterns of RGS proteins in CRC, identifying Regulator of G protein
- Systems modeling of oncogenic G-protein and GPCR signaling reveals unexpected differences in downstream pathway activation
< GPCR News < GPCRs in Oncology and Immunology Systems modeling of oncogenic G-protein and GPCR signaling In the present study, we first develop a mechanistic mathematical model of a G-protein coupled receptor
- G protein-coupled estrogen receptor (GPER)/GPR30 forms a complex with the β1-adrenergic receptor, a membrane-associated guanylate kinase (MAGUK) scaffold protein, and protein kinase A anchoring protein (AKAP) 5 in MCF7 breast cancer cells
< GPCR News < GPCRs in Oncology and Immunology G protein-coupled estrogen receptor (GPER)/GPR30 forms A anchoring protein (AKAP) 5 in MCF7 breast cancer cells Published date January 10, 2024 Abstract "G protein-coupled receptor 30 (GPR30), also named G protein-coupled estrogen receptor (GPER), and the β1 -adrenergic receptor (β1AR) are G protein-coupled receptors (GPCR) that are implicated in breast cancer
- Activation of PI3K/Akt pathway by G protein-coupled receptor 37 promotes resistance to cisplatin-induced apoptosis in non-small cell lung cancer
< GPCR News < GPCRs in Oncology and Immunology Activation of PI3K/Akt pathway by G protein-coupled receptor Among eukaryotes, the G protein-coupled receptor (GPCR) family stands as the largest group of membrane As a member of the GPCR family, G protein-coupled receptor 37 (GPR37) exhibits unknown functions in tumors
- Prediction of survival and immunotherapy response by the combined classifier of G protein-coupled receptors and tumor microenvironment in melanoma
Oncology and Immunology Prediction of survival and immunotherapy response by the combined classifier of G Wei , Tianyi Zhang , Yu Zhu , Jia Feng , Feng Qin , Yanwen Yang , Chuanyuan Wei , Jianying Gu Tags G
- Ep 70 with Dr. Stephen Ferguson
Marc G. Caron at Duke University (1994-1997), where he and his colleagues investigated the role of G protein-coupled receptor kinases and beta-arrestin in regulating G protein-coupled receptor endocytosis, trafficking His research career has focused on the investigation of the regulation of G protein-coupled receptors
- Ep 69 with Dr. Stephen Ferguson
Marc G. Caron at Duke University (1994-1997), where he and his colleagues investigated the role of G protein-coupled receptor kinases and beta-arrestin in regulating G protein-coupled receptor endocytosis, trafficking His research career has focused on the investigation of the regulation of G protein-coupled receptors
- [Inhibitory effect of downregulating G protein-coupled receptor class C group 5 member A expression on lipopolysaccharide-induced inflammatory response in human gingival fibroblasts]
< GPCR News < GPCRs in Oncology and Immunology [Inhibitory effect of downregulating G protein-coupled fibroblasts] Published date March 27, 2024 Abstract "Objective: To clarify the effect and the mechanism of G response in human gingival fibroblasts (GFs), thus to provide a foundation for delving into the role of G
- AGPCR 24 Session II
Agenda Session II AGPCR signaling pathways and trafficking Localization of putative ligands for adhesion G Erwin G. Proteolytic Processing, Trafficking And Signalling Pal Kasturi Localization of putative ligands for adhesion G Erwin G. Erwin G.
- Trainee Symposium II
GPCR Title: Balancing G Protein Selectivity and Efficacy in the Adenosine A2A Receptor About Louis-Philippe My primary research focus lies in gaining deeper insights into the structural mechanisms governing G protein-coupled receptors (GPCRs) and G protein activation. GPCR Title: Development of a Transgenic Mouse Platform for the Detection of Endogenous G protein Activity Mikel Garcia-Marcos which investigates GPCR and G protein signaling" Remi Janicot on the web Boston University
- Ep 125 with Dr. Gregory Tall
Tall moved upstairs to conduct his postdoctoral work on heterotrimeric G proteins and the novel interactor the Tall lab are to understand the basic mechanism by which Ric-8 proteins fold all heterotrimeric G protein alpha subunits, to exploit a Ric-8-based technology to purify recombinant G proteins and to use the G proteins in assays to explore the mechanisms of action of the 33-member adhesion GPCR family or
- Unveiling Non-Canonical Functions for Gαq Signaling Pathways
she has participated in the identification and characterization of proteins that act at the level of G proteins and which are part of a multimolecular signaling complex (AGS, de “Activators of G-protein signaling Ribas has also described a new protective role of G protein-coupled receptor kinase 2 (GRK2), a known
- Ep 131 with Dr. Richard Premont
For this, we have worked in three main areas: the regulation of G protein-coupled receptor signaling particularly by the G protein-coupled receptor kinase (GRK) – beta-arrestin system, the coordination of heterotrimeric G protein, small GTP-binding protein and protein kinase pathways by GIT/PIX scaffolding
- Ep 133 with Dr. Richard Premont
For this, we have worked in three main areas: the regulation of G protein-coupled receptor signaling particularly by the G protein-coupled receptor kinase (GRK) – beta-arrestin system, the coordination of heterotrimeric G protein, small GTP-binding protein and protein kinase pathways by GIT/PIX scaffolding
- Ep 132 with Dr. Richard Premont
For this, we have worked in three main areas: the regulation of G protein-coupled receptor signaling particularly by the G protein-coupled receptor kinase (GRK) – beta-arrestin system, the coordination of heterotrimeric G protein, small GTP-binding protein and protein kinase pathways by GIT/PIX scaffolding
- Removing the GPCR-mediated brake on exocytosis enhances insulin action, promotes adipocyte browning, and protects against diet-induced obesity
Her laboratory has been involved in studying G protein coupled signal transduction for many years and has made key discoveries in G protein structure and mechanisms of activation by GPCRs and activation cardiovascular system and regulation of vesicular exocytosis mediated by Gi/o-coupled receptors by G clocks and melatonin synthesis in the avian retina; her postdoctoral work investigated the role of the G
- AGPCR 24 Session V
function Structural Determinants Of GAIN Domain Autoproteolysis And Cleavage Resistance Of Adhesion G Seufert Structural Determinants Of GAIN Domain Autoproteolysis And Cleavage Resistance Of Adhesion G Fabian Pohl Abstract "The GPCR autoproteolysis-inducing (GAIN) domain is a hallmark feature of adhe-sion G-protein module of fourteen domains which regulates signaling Sumit Bandekar Abstract "Cadherin EGF Laminin G seven-pass G-type receptors (CELSRs) are conserved adhesion G protein-coupled receptors; they are essential
- GPCR Retreat 2023 | Dr. GPCR Ecosystem
November 2-4, 2023 We are pleased to welcome you at Le Château Montebello , the 22nd Annual Great Lakes G activity-modifying proteins or RAMPs regulate GPCR function, is confirmed as Plenary Speaker of the inaugural Marc G. Additionally, there will be a Marc G.
- AGPCR 24 Session I
Activation Mechanisms of Adhesion GPCRs Yan Zhang Heterogeneity of Tethered Agonist Signaling in Adhesion G Protein-Coupled Receptors Andrew Dates Discriminating between the extracellular scaffolding and G protein ) Structural Insights into the Activation Mechanisms of Adhesion GPCRs Yan Zhang Abstract "Adhesion G As an undergraduate, he studied opioid receptor trafficking and G protein conformational dynamics in Pan, Michael Holinstat and Gregory G.