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350 items found for "Wenmiao Li"
- CircFKBP5 Suppresses Apoptosis and Inflammation and Promotes Osteogenic Differentiation
This work focussed on exploring the functions and mechanism of circFKBP5 in DPSC dysfunction evoked by lipopolysaccharide Authors Cuiwei Liang , Wenmiao Li , Qian Huang , Qitao Wen .
- Identification of a G-protein coupled receptor-related gene signature through bioinformatics analysis to construct a risk model for ovarian cancer prognosis
The levels of GPCRRGs were examined in normal and OV cell lines using quantitative reverse-Etranscription Authors Shaohan Ma, Ruyue Li, Guangqi Li, Meng Wei, Bowei Li, Yongmei Li, Chunfang Ha Tags G protein-coupled
- RGS20 promotes non-small cell lung carcinoma proliferation via autophagy activation and inhibition of the PKA-Hippo signaling pathway
Authors Xiaoyan Ding , Xiaoxia Li , Yanxia Jiang , Yujun Li , Hong Li , Lipeng Shang , Guilin Feng , Huhu Zhang , Ziyuan Xu , Lina Yang , Bing Li , Robert Chunhua Zhao Tags Autophagy , NSCLC , PKA-Hippo
- Elucidation of active components and target mechanism in Jinqiancao granules for the treatment of prostatitis and benign prostatic hyperplasia
Ultra-performance liquid chromatography-mass spectrometry was used for compound separation and characterization Nitric acid (NO) inhibition was tested on the macrophage cell line RAW264.7. Authors Han Zhou, Tao Hou, Aijin Shen, Wenyi Yu, Liangliang Zhou, Wenjie Yuan, Wanxian Wang, Yumin Yao , Jixia Wang, Yanfang Liu, Xinmiao Liang Tags Benign prostatic hyperplasia , G-protein coupled receptor
- Orphan receptor GPR50 attenuates inflammation and insulin signaling in 3T3-L1 preadipocytes
secretion deficiencies and systemic insulin resistance (IR) in adipose tissue, skeletal muscle, and the liver Furthermore, GPR50 knockout in the 3T3-L1 cell line suppressed PPAR-γ expression. Authors Zhenyu Yao, Jun Meng, Jing Long, Long Li, Weicong Qiu, Cairong Li, Jian V Zhang, Pei-Gen Ren
- GPR37 promotes colorectal cancer against ferroptosis by reprogramming lipid metabolism via p38-SCD1 axis
GPCRs in Oncology and Immunology GPR37 promotes colorectal cancer against ferroptosis by reprogramming lipid that GPR37 protects cancer cells from ferroptosis by upregulating SCD1 expression, thereby modulating lipid Mechanistic studies have shown that GPR37 modulates lipid metabolism in tumor cells by promoting SCD1 Authors Jiamin Zhou, Xigan He, Weixing Dai, Qingguo Li, Zhen Xiang, Yixiu Wang, Ti Zhang, Weiqi Xu, Lu Wang, Anrong Mao Tags Ferroptosis , GPR37 , Lipid metabolism , SCD1 , p38 Source Contribute to the GPCR
- GPCR signaling contributes to immune characteristics of microenvironment and process of EBV-induced lymphomagenesis
Sheng-Yue Wang , Hai Fang , Rui-Hong Zhang , Yue Zhu , Hong-Mei Yi , Xu-Feng Jiang , Jia-Yi Chen , Li Wang , Peng-Peng Xu , Sai-Juan Chen , Wei-Li Zhao Tags CCR1 , Epstein-Barr virus , Lymphoma , Microenvironment
- Ep 122 with Dr. Nicolas Gilles
GPCR Podcast << Back to podcast list Dr. Nicolas Gilles About Dr. Nicolas Gilles "Dr. His strongest expertise lies in therapeutic target identification and all the steps from venom manipulations When the pharmacological properties of these new ligands are deemed exceptional, a lead optimization Nicolas Gilles on the web Google Scholar LinkedIn Dr. GPCR Thanks for listening to this podcast episode This short survey will help us understand your needs
- Unbiased multitissue transcriptomic analysis reveals complex neuroendocrine regulatory networks mediated by spinal cord injury-induced immunodeficiency
Authors Hong Zeng , Li Cheng , De-Zhi Lu , Shuai Fan , Ke-Xin Wang , Li-Li Xu , Bin Cai , Mou-Wang Zhou
- Role and recent progress of P2Y12 receptor in cancer development
Authors Yanni Xi, Zhenya Min, Mianxue Liu, Xueqin Li, Zhao-Hua Yuan Tags P2Y12R , P2Y12R inhibitors ,
- Ep 150 with Dr GPCR Team
Monserrat Avila Zozaya on the web LinkedIn Antony Boucard Lab Dr. John Azietaku on the web LinkedIn Dr. GPCR About Ya-Tzu Li Ya-Tzu is a Master's student at the University of South Florida, utilizing large-scale Ya-Tzu Li on the web LinkedIn Dr. Cam Sinh Lu on the web LinkedIn Dr.
- The binding mechanism of an anti-multiple myeloma antibody to the human GPRC5D homodimer
Authors Pengfei Yan, Xi Lin, Lijie Wu, Lu Xu, Fei Li, Junlin Liu, Fei Xu Source Contribute to the GPCR
- Ep 27 with Dr. Robert J. Lefkowitz
GPCR Podcast << Back to podcast list Dr. Robert J. His legacy lies in the numerous discoveries he and his team made in the GPCR field and in all those who GPCR Ecosystem Thanks for listening to this podcast episode This short survey will help us understand Listen and subscribe to where you get your podcasts. << Previous Podcast Episode Next Podcast Episode
- About Us | Dr. GPCR Ecosystem
GPCR programs including the: Summit Virtual Cafe Listening to podcast episodes before these are released with your target audience Access to all member perks for your entire team Add your product and service listings Monserrat Avila Zozaya Get in touch Scientific Associate Ya-Tzu Li Get in touch Scientific Associate
- CB2 stimulation of adipose resident ILC2s orchestrates immune balance and ameliorates type 2 diabetes mellitus
Authors Pedram Shafiei-Jahani, Shi Yan, Mohammad H Kazemi, Xin Li, Amitis Akbari, Kei Sakano, Yoshihiro
- CCL5-producing migratory dendritic cells guide CCR5+ monocytes into the draining lymph nodes
Authors Kavita Rawat , Anita Tewari , Xin Li , Arlind B Mara , William T King , Sophie L Gibbings , Chinaza
- Inhibition of Relaxin Autocrine Signaling Confers Therapeutic Vulnerability in Ovarian Cancer
Rottapel’s research interests lies in the elucidation of signal transduction pathways in cancer, immune The Rottapel Lab Ontario Institute for Cancer Research University of Toronto Pubmed Google Scholar LinkedIn
- Enterococcus-derived tyramine hijacks α2A-adrenergic receptor in intestinal stem cells to exacerbate colitis
tyramine, primarily produced by Enterococcus via tyrosine decarboxylase (tyrDC), serves as a microbial ligand Our findings highlight a microbial ligand-GPCR pair in ISCs, revealing a causal link between microbial Authors Chaoliang Li , Panrui Zhang , Yadong Xie , Shishan Wang , Meng Guo , Xiaowei Wei , Kaiguang Zhang
- Student Flash Presentations | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Abhishek Kumar Singh Investigating The Role of ADGRB3 Loss of Expression in Brain Tumor Formation in Li-Fraumeni Scholar X (Twitter) Investigating The Role of ADGRB3 Loss of Expression in Brain Tumor Formation in Li-Fraumeni Syndrome Alex Torrelli-Diljohn Abstract "Li-Fraumeni syndrome (LFS) is a rare cancer predisposition Authors & Affiliations "Vukadin L, Park B, Mohamed M, Li H, Elkholy A, Torrelli-Diljohn A, Kim JH, Jeong He is interested in working on Li-Fraumeni syndrome and helping patients afflicted with this condition
- RGS5 maintaining vascular homeostasis is altered by the tumor microenvironment
Xu Wang , Ya-Kun Gao , Dan-Dan Zhang , Xiao-Fu Huang , Yu Song , Wen-Di Zhang , Rui-Juan Guo , Han Li
- GPR97 depletion aggravates imiquimod-induced psoriasis pathogenesis via amplifying IL-23/IL-17 axis signal pathway
It was found that significantly aggravated psoriasis-like lesion in GPR97-/- mice. investigations indicated that beclomethasone dipropionate (BDP), an agonist of GPR97, attenuated the psoriasis-like Authors Yaoxin Gao, Weirong Zhan, Dandan Guo, Haizhen Lin, Muhammad Asad Farooq, Chenxu Jin, Li Zhang
- Systems Pharmacodynamic Model of Combination Gemcitabine and Trabectedin in Pancreatic Cancer Cells. Part II: Cell Cycle, DNA Damage Response, and Apoptosis Pathways
To investigate potential mechanisms underlying this synergistic pharmacodynamic interaction, liquid chromatography-mass Authors Xin Miao , Gilbert Koch , Shichen Shen , Xue Wang , Jun Li , Xiaomeng Shen , Jun Qu , Robert
- Prediction of survival and immunotherapy response by the combined classifier of G protein-coupled receptors and tumor microenvironment in melanoma
Authors Kangjie Shen , Qiangcheng Wang , Lu Wang , Yang Yang , Min Ren , Yanlin Li , Zixu Gao , Shaoluan
- Interplay between G protein-coupled receptors and nanotechnology
of the majority of marketed drugs, the poor pharmacokinetics and physicochemical properties of GPCR ligands greatly limit their clinical applicability. Nanotechnology, as versatile techniques, can encapsulate GPCR ligands to assemble synthetic nano-GPCRs Moreover, endosomal delivery of GPCR ligands by nanoparticles can precisely initiate sustained endosomal Authors Yuhong Jiang , Yuke Li , Xiujuan Fu , Yue Wu , Rujing Wang , Mengnan Zhao , Canquan Mao , Sanjun
- Coronavirus Porcine Epidemic Diarrhea Virus Utilizes Chemokine Interleukin-8 to Facilitate Viral Replication by Regulating Ca2+ Flux
epidemic diarrhea virus (PEDV) infection in African green monkey kidney epithelial cells (Vero) and Lilly Authors Xuyang Guo , Yingtong Feng , Xiaojing Zhao , Shuang Qiao , Zhiqian Ma , Zhiwei Li , Haixue Zheng
- Regulator of G protein signaling protein 6 alleviates acute lung injury by inhibiting inflammation and promoting cell self-renewal in mice
In an in vivo study, the effects of RGS6 knockout were studied in a mouse model of ALI induced by lipopolysaccharide Authors Juan Song , Miao Li , Cuicui Chen , Jian Zhou , Linlin Wang , Yu Yan , Jun She , Lin Tong , Yuanlin
- Trainee Symposium II
Back to schedule Trainee Symposium II Date & Time Thursday, November 2nd / 3:00 PM - 4:00 PM Title: Linking My primary research focus lies in gaining deeper insights into the structural mechanisms governing G protein engineering, receptor pharmacology, and structural biology to study how different types of ligands
- Removing the GPCR-mediated brake on exocytosis enhances insulin action, promotes adipocyte browning, and protects against diet-induced obesity
2,3,*, Analisa Thompson Gray 2, Feyisayo Adegboye 2, Ainsley McDonald-Boyer 3, Fubiao Shi 1, Dianxin Liu 1, Jose Maldonado 5, Jiesi Feng 4, Yulong Li 4, Simon Alford 5, Julio E. The Department’s strengths lie in GPCR signal transduction and neuroscience, and she has expanded it She gave the Fritz Lipmann Lecture at ASBMB in 2001. " Heidi Hamm on the web The Hamm Lab Vanderbilt School of Medicine Pubmed Google Scholar LinkedIn Twitter Dr.