September 2022 "The activation of phospholipase C (PLC) is thought to have a key role in the cardiomyocyte

This Week’s Highlights: Celebrating Excellence: Wessel A. C. Burger , Arthur Christopoulos , David M. Crinetics Pharmaceuticals Announces September 2024 Inducement Grants Under Nasdaq Listing Rule 5635(c)

Here, we provide evidence that distal carboxyl-terminal tail (C-tail), but not proximal, phosphorylation site-directed mutagenesis and bioluminescence resonance energy transfer approaches that distal, not proximal, C-tail In addition, we show that GPCRs that have similarly positioned C-tail phosphoresidues are also able to However, although necessary for some GPCRs, we found that distal C-tail sites might not be sufficient In conclusion, this study provides evidence that distal C-tail phosphorylation sites specify GRK-βarrestin-mediated

< GPCR News < GPCRs in Oncology and Immunology [1,2,4]Triazolo[1,5-c]pyrimidines as Tools to Investigate In this work, a structural investigation on the two position of the [1,2,4]triazolo[1,5-c]pyrimidines adenosine receptor antagonists like the ethyl 2-(4-methoxyphenyl)-5-(methylamino)-[1,2,4]triazolo[1,5-c]

Josh C Snyder (2012) Dr. William Wetsel (current) Memories our panelists shared with us Thanks for listening to this podcast episode

GPCRs in Oncology and Immunology [Inhibitory effect of downregulating G protein-coupled receptor class C 2024 Abstract "Objective: To clarify the effect and the mechanism of G protein-coupled receptor class C