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25 items found for "Wessel A. C. Burger"
- Ep 102 with Dr Caron Tribute Part 3
Josh C Snyder (2012) Dr. William Wetsel (current) Memories our panelists shared with us Thanks for listening to this podcast episode
- GprC of the nematode-trapping fungus Arthrobotrys flagrans activates mitochondria and reprograms fungal cells for nematode hunting
The C. elegans ascaroside-sensing GPCR, SRBC66 and GPCRs of many fungi are also predicted for dual localization An SRBC64/66-GprC chimaeric protein was functional in A. flagrans, and C. elegans SRBC64/66 and DAF38 Authors Xiaodi Hu, David S Hoffmann, Mai Wang, Lars Schuhmacher, Maria C Stroe, Birgit Schreckenberger
- Natural carboxyterminal truncation of human CXCL10 attenuates glycosaminoglycan binding, CXCR3A signaling and lymphocyte chemotaxis, while retaining angiostatic activity
However, the biological effect of natural posttranslational processing of CXCL10 at the carboxy (C)-terminus We studied CXCL10(1-73), lacking the four endmost C-terminal amino acids, which was previously identified In contrast, loss of the four endmost C-terminal residues did not affect the inhibitory properties of Conclusion: Our study shows that the C-terminal residues Lys74-Pro77 of CXCL10 are important for GAG
- Structural Basis for the Recognition of GPRC5D by Talquetamab, a Bispecific Antibody for Multiple Myeloma
G-protein-coupled receptor class C group 5 member D (GPRC5D), an orphan GPCR predominantly expressed Jeong, Junhyeon Park, Geun Young Mo, Jinwoo Shin, Yunje Cho Tags GPRC5D , Multiple myeloma , class C
- Simultaneous activation of CXC chemokine receptor 4 and histamine receptor H1 enhances calcium signaling and cancer cell migration
receptor H1 enhances calcium signaling and cancer cell migration Published date February 1, 2023 Abstract "C-X-C
- Ep 23 with Dr. Qing Fan
Qing is a structural biologist interested in the molecular mechanisms controlling how class C GPCRs transmit
- Exploration of prognostic and treatment markers in hepatocellular carcinoma via GPCR-related genes analysis
GPCR-related risk score containing eight GPCR-related genes (atypical chemokine receptor 3 (ACKR3), C-C
- Ep 20 with Dr. Jennifer Pluznick
Pluznick discovered that olfactory receptors in mice are also expressed in their kidneys and blood vessels
- Ep 140 with Dr Alix A J Rouault
described the molecular mechanisms of MRAP2 regulation of the GHSR1a, and where I notably developed the C-terminal This theory states that the post-translational modification of GHSR1a’ C-terminal tail is not a docking
- Chemoattractant receptor signaling in humoral immunity
binding, GPCRs are phosphorylated by different GPCR kinases (GRKs) at distinct sites on the receptor C
- Phase 1/2 study of sorafenib added to cladribine, high-dose cytarabine, G-CSF, and mitoxantrone in untreated AML
, Pamela S Becker , Jacob S Appelbaum , Janis L Abkowitz , Johnnie J Orozco , Siobán B Keel , Paul C
- CCL5-producing migratory dendritic cells guide CCR5+ monocytes into the draining lymph nodes
identified LN mononuclear phagocytes as monocytes, resident, or migratory type 1 and type 2 conventional (c)
- Ep 87 with Dr. Bianca Plouffe
molecular mechanisms involved in the opposite regulation of dopamine D1 and D5 receptors by protein kinase C.
- Session II | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
G-protein-coupled receptor (aGPCR) family, known to play a role in myelination, placentation, blood vessel GPCR-autoproteolysis site (GPS) enclosed within the larger GAIN domain to generate the N-terminal (NTF) and C-terminal
- NPFF stimulates human ovarian cancer cell invasion by upregulating MMP-9 via ERK1/2 signaling
Authors Ze Wu , Qiongqiong Jia , Boqun Liu , Lanlan Fang , Peter C K Leung , Jung-Chien Cheng Tags Invasion
- C5aR2 receptor: The genomic twin of the flamboyant C5aR1
generating highly refined model structures of C5aR2, respectively in free (inactive), complexed to C-terminal
- Delivery of US28 by incoming HCMV particles rapidly attenuates Akt activity to suppress HCMV lytic replication in monocytes
Biswas, Michael J Miller, Julia E Myers, Stephen M Matthews, Amanda B Wass, Christine M O'Connor, Gary C
- Gi/o GPCRs drive the formation of actin-rich tunneling nanotubes in cancer cells via a Gβγ/PKCα/FARP1/Cdc42 axis
Subsequent signaling analysis reveals a strict requirement of phospholipase C β3 (PLCβ3) and its downstream
- Ep 113 with Dr. Prasenjit Saha
marker for CVD as it causes serious fatal conditions such as thrombus formation, which can block blood vessels
- Session V | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
We assign the N-terminal CADH1-8 module as necessary for cell adhesion and we show the C-terminal CAHD9 Authors & Affiliations "Garbett, Krassimira, Kordon, Szymon P., Shearer, Tanner, Sando, Richard C.*,
- RGS5 maintaining vascular homeostasis is altered by the tumor microenvironment
expression was increased in the triple-negative breast cancer (TNBC) tissues and in the tumor blood vessels
- Session I | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Affiliations "Rosell, Júlia (1) Holmkvist, Jesper L. (1) Arastoo, Mohammad Reza (1) Vejre, Phillip C. Burruss (Harvard Medical School); Andrew Kruse (Harvard Medical School); Stephen C.
- Session III | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
autoproteolytic cleavage in the GAIN domain, creating a heterodimer of an N-terminal fragment (NTF) and a C-terminal
- Terms and Conditions | Dr. GPCR Ecosystem
that interferes with or disrupts the integrity or performance of the Services or its components, or (c) ; (b) changes to conform and adapt to technical requirements of connecting networks or devices and (c)
- Posters | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
hypothesis, we created WNT-like MB cell lines stably expressing tet-on wild-type BAI3 or a BAI3 lacking the C-terminal