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8 items found for "Won-Ki Huh"
- Actions of Parathyroid Hormone Ligand Analogues in Humanized PTH1R Knockin Mice
To overcome this potential uncertainty, we used a homologous recombination-based knockin (KI) approach The resulting homozygous hPTH1R-KI (humanized) mice were healthy over at least 10 generations and showed
- GPCR Agonist-to-Antagonist Conversion: Enabling the Design of Nucleoside Functional Switches for...
We synthesized and characterized a novel A2AAR antagonist, 2 (LJ-4517), with Ki = 18.3 nM.
- Discovery of 3(2-aminoethyl)-thiazolidine-2,4-diones as a novel chemotype of sigma-1 receptor ligand
displacement of the radioligand at 10 µM concentration with compound 6c resulting in 100% displacement and a Ki
- HBx induces hepatocellular carcinogenesis through ARRB1-mediated autophagy to drive the G 1/S cycle
; MAP1LC3B/LC3: microtubule associated protein 1 light chain 3 beta; MKI67: marker of proliferation Ki
- Glucagon receptor-mediated regulation of gluconeogenic gene transcription is endocytosis-dependent..
We show that epitope-tagged GCGRs undergo clathrin- and dynamin-dependent endocytosis in HEK293 and Huh
- 📰 GPCR Weekly News, February 27 to March 5, 2023
Charité to Advance Development of Precision Medicine Platform Sosei Heptares and Neurocrine Biosciences won
- 📰 GPCR Weekly News
Industry News Sosei Heptares and Neurocrine Biosciences won Out-Licensing Deal of the Year from Locust
- Ode to GPCRs
Carlsson, and Paul Greengard for research on signal transduction in the nervous system.[48–54] Carlsson won