GPCR Podcast << Back to podcast list Yao Lu (Jackie) About Yao Lu (Jackie) "Jackie is a Ph.D. student small molecules for their pre-clinical efficacy and to support the design of novel therapeutics. " Yao Lu

During that time, I investigated the effect of lung cancer-related mutations in the GAIN domain of the GPCR About Cam Sinh Lu Cam Sinh Lu is a PhD student at Monash Institute of Pharmaceutical Sciences, Monash Cam Sinh Lu on the web LinkedIn Dr.

Authors Pengfei Yan, Xi Lin, Lijie Wu, Lu Xu, Fei Li, Junlin Liu, Fei Xu Source Contribute to the GPCR

Huang, Yumiao Zhao, Chan Zhang, Xiyun Ye, Ying Huang, Ruth Nussinov, Junke Zheng, Mingyao Liu, Weiqiang Lu

The lung cancer cell line H1299-BRS3 was treated with MK-5046, an agonist of BRS3, for different durations Authors Miao Guo , Yan Zhang , Lehao Wu , Ye Sheng , Jiaqi Zhao , Zeyuan Wang , Huiyu Wang , Lu Zhang

Dai , Wen-Fang Wang , Hao Zhang , Chao-Fu Wang , Tong Yin , Shu Cheng , Hui-Juan Zhong , Shan-He Yu , Lu

Authors Trang T T Nguyen , Wen Lu , Wandi S Zhu , K Mark Ansel , Hong-Erh Liang , Arthur Weiss .

Authors Hong Zeng , Li Cheng , De-Zhi Lu , Shuai Fan , Ke-Xin Wang , Li-Li Xu , Bin Cai , Mou-Wang Zhou

Authors Yuxin Wang , Bao Jin , Xiangan Wu , Jiali Xing , Baoluhe Zhang , Xiaokun Chen , Xiao Liu , Xueshuai

Bernadyn, Mariane Nascimento, Xinyi Lu, Pauline L. Pan, Michael Holinstat and Gregory G.

News < GPCRs in Oncology and Immunology Regulator of G protein signaling protein 6 alleviates acute lung protein-coupled receptor (GPCR)-related genes and differentially expressed genes (DEGs) in an acute lung RGS6 plays a protective role in ALI not only in early inflammatory responses but also in endogenous lung Li , Cuicui Chen , Jian Zhou , Linlin Wang , Yu Yan , Jun She , Lin Tong , Yuanlin Song Tags Acute lung

G protein-coupled receptor 37 promotes resistance to cisplatin-induced apoptosis in non-small cell lung cancer Published date September 21, 2023 Abstract "Objectives: Lung cancer is a major public health protein-coupled receptor 37 (GPR37) exhibits unknown functions in tumors, particularly in non-small-cell lung

< GPCR News < GPCRs in Oncology and Immunology A2aR on lung adenocarcinoma cells: A novel target for Here, we identify that A2aR is specifically expressed on tumor cells from lung adenocarcinoma (LUAD) We hypothesize that blocking A2aR on LUAD cells will inhibit the role of TAMs and control tumor growth Constructing models of TAMs and LUAD mice, we find that A2aR highly expressed on LUAD cells promotes blockade of A2aR may support a novel and potent therapeutic option for LUAD."

Immunology Minireview: functional roles of tissue kallikrein, kinins, and kallikrein-related peptidases in lung Published date July 3, 2023 Abstract "Despite campaigns and improvements in detection and treatment, lung One approach to treating patients suffering from lung cancer is to target surface receptors overexpressed Since lung cancer is often diagnosed in advanced stages, our efforts should focus on early diagnosis, Furthermore, their modulation could be considered as a promising approach in lung cancer therapeutics

< GPCR News < GPCRs in Oncology and Immunology Deciphering the genetic landscape of lumpy skin disease virulence through comprehensive genome sequence analysis in India Published date May 23, 2024 Abstract "Lumpy Sai Balaji, V Gairola, D Poloju, S Gulzar, K P Singh, R K Singh, G K Sharma Tags Genome sequence , Lumpy

Frederik Leeb-Lundberg (1984) Dr. Robert Lefkowitz (1973) Dr. Lee Limbird (1973) Dr.

Washington University, the NIH and UCLA, he pursued his postdoctoral studies with Allan Bernstein at the Lunenfeld

DiGiacomo , Mariola Ferreras-Gutierrez , Shiva Dastjerdi , Alain Ibáñez de Opakua , Jong-Chan Park , Alex Luebbers

Monserrat Avila Zozaya "My doctoral research was focused on investigating the cellular effects of missense lung

Such pro-inflammatory immune cells may travel to tissues such as the brain, the lung, the kidney etc

Authors Mor Oron-Herman , David Kirmayer , Amelie Lupp , Stefan Schulz , Genady Kostenich , Michel Afargan

formation in human intestinal dendritic cells Published date October 29, 2024 Abstract "The intestinal lumen G-protein-coupled receptors (GPCRs) sense metabolites and can act as key mediators that translate gut luminal human gut organoid coculture system, we show that cDC1s extend their dendrites toward pyruvate on the luminal activation via pyruvate enhances the fundamental function of cDC1 by allowing efficient uptake of gut luminal

Authors Luna Dillemans , Karen Yu , Alexandra De Zutter , Sam Noppen , Mieke Gouwy , Nele Berghmans ,

multimeric complexes larger than dimers in MDA-MB-231 human breast cancer cells and in HCC4006 human lung

Mesothelioma and lung cancer induced by exposure to carcinogenic (e.g., certain asbestos) fibers in humans This theory is reviewed, implications of this theory are discussed in relation to mesothelioma and lung Author Kenneth T Bogen Tags Asbestos , Cytotoxicity , Inflammation , Lung cancer , Mesothelioma , Mutation

Monserrat Avila Zozaya "My doctoral research was focused on investigating the cellular effects of missense lung Van Meir pursued postdoctoral work at the Ludwig Institute for Cancer Research in San Diego and joined

Authors Chakit Arora, Marin Matic, Luisa Bisceglia, Pierluigi Di Chiaro, Natalia De Oliveira Rosa, Francesco Carli, Lauren Clubb, Lorenzo Amir Nemati Fard, Giorgos Kargas, Giuseppe R Diaferia, Ranka Vukotic, Luana

CELSR1 is reactivated in luminal-type ductal carcinomas. Notably, our pilot data from luminal-type breast cancer cell lines representative of breast carcinomas specific hypothesis that biased expression of CELSR1 isoforms will predict invasive potential of a luminal tumour invasive mechanism (b) quantify CELSR1 isoform expression (mRNA and protein) within patient luminal