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receptor class C group 5 member A expression on lipopolysaccharide-induced inflammatory response in human receptor class C group 5 member A (GPRC5A) on lipopolysaccharide (LPS)-induced inflammatory response in human RT-qPCR results showed that the gene expression levels of GPRC5A at different time point (2, 6, 12, 24 h) group (0.004±0.000, 0.004±0.000, 0.002±0.000, 0.007±0.000) (all P<0.001), respectively, and peaked at 6 h. Authors Y H Hu , L L Shang , S H Ge Source Contribute to the GPCR News Coming soon Become a Contributor

< GPCR News < GPCRs in Oncology and Immunology Pharmacological inhibition of neuropeptide Y receptors migration, proliferation, and signaling Published date May 30, 2023 Abstract "Background: Neuropeptide Y (NPY) is an abundant neurohormone in human breast carcinomas that acts on a class of G-protein coupled In human breast tumor tissue, we show via immunofluorescence that NPY5R protein levels and colocalization

mice at 10-12 weeks of age were given an oral gavage of ethanol (3 g/kg) or maltose (5.4 g/kg) at 1-4 h After 2-24 h, brains were collected for the analysis of gene expression by RT-PCR or protein expression microglia and peritoneal macrophages were isolated from adult WT mice and treated with 25 mM ethanol for 4 h and then with LPS (100 ng/ml) followed by 10 nM synaptamide for 2 h for gene expression and 12 h for

Harris , Alena Scharmacher , Hanna Graßhoff , Kristina Sterner , Susanne Schinke , Nadja Käding , Jens Y Humrich , Otávio Cabral-Marques , Joana P Bernardes , Neha Mishra , Thomas Bahmer , Jeanette Franzenburg

Reno Brooks, Xuesong Wang, Willem Jespers, Marina Gorostiola González, Gerard J P van Westen, Erik H J Danen, Laura H Heitman Tags 5-HT(2C) receptor , G protein-coupled receptor , cancer , mutation , serotonin

Identified intolerant residues with reported cancer-linked mutations RGS14-R173C/H and RGS4-K125Q/E126K SIGNIFICANCE STATEMENT: Human genetic variant/mutation information has expanded rapidly in recent years Authors Carolina Montañez-Miranda , Riley E Perszyk , Nicholas H Harbin , Jennifer Okalova , Suneela

hosted in the vibrant heart of Mexico City at the prestigious venue, CINVESTAV - Centro de Investigación y About the venue Cinvestav: Centro de investigación y de Estudios Avanzados del IPN Av.

Authors Carlos H Hiroki , Bryan G Yipp Source Contribute to the GPCR News Coming soon Become a Contributor

nematode-trapping fungus Arthrobotrys flagrans activates mitochondria and reprograms fungal cells for nematode hunting dual localization of GprC in A. flagrans resembles the localization of the cannabinoid receptor CB1 in humans Authors Xiaodi Hu, David S Hoffmann, Mai Wang, Lars Schuhmacher, Maria C Stroe, Birgit Schreckenberger

< GPCR News < GPCRs in Oncology and Immunology TIPE proteins control directed migration of human T cells Using both gene knockdown and biochemical methods, we demonstrated here that two human TIPE family members , TNFAIP8 and TIPE2 were essential for directed migration of human CD4+ T cells. Collectively, our work describes a new mechanistic paradigm for how human T cells integrate GPCR and Authors Jiyeon Yu , Ali Zamani , Jason R Goldsmith , Zienab Etwebi , Chin Nien Lee , Youhai H Chen ,

He has published more than 800 scientific publications, with an H-index of 115.

of the endocannabinoid system, is expressed on both visceral adipose tissue (VAT)-derived murine and human Authors Pedram Shafiei-Jahani, Shi Yan, Mohammad H Kazemi, Xin Li, Amitis Akbari, Kei Sakano, Yoshihiro Sakano, Benjamin P Hurrell, Omid Akbari Tags CB2 , CP: Immunology , CP: Metabolism , ILC2 , T2DM , adipose

Ribeiro H factor is 28, according to Web of Science, and she is an affiliated member of the Brazilian These drugs were shown to be very effective to rescue the cell death observed in a mouse model of Huntington

mutations found in patient samples derived from the Genomic Data Commons and compared it to the natural human Authors Bongers B J , Gorostiola González M , Wang X , van Vlijmen HWT , Jespers W , Gutiérrez-de-Terán H

Bruns has over 80 publications and 11,000 citations, with an h-index of 47. Dr. Robert F.

Our group previously reported that LPA induces production of CCN1 protein in human prostate cancer cell lines within 2-4 h.

Abstract Coming Soon Authors and Affiliations Gross JD -1 (lead author, presenter) Kohlenbach LM -2 Zhou Y

His papers were cited over 28,000 times (H-index – 81, ISI Web of Science). In 2018-2020, Raul R.

His work received more than 30,000 citations yielding an h-index of 95. Michel’s lab with some of his postdocs and although I was never officially a member of the lab, I am humbled

Jiawei Zhou , Jianqiang Guo , Yafeng Liu , Chao Liang , Wenyang Wang , Yingru Xing , Jing Wu , Dong Hu

Abkowitz , Johnnie J Orozco , Siobán B Keel , Paul C Hendrie , Bart L Scott , M Cristina Ghiuzeli , Elihu H

His work received more than 30,000 citations yielding an h-index of 95.

Giros has published more than 200 publications with an H factor of 79 and 32,000 citations (Google Scholar

Authors Guangrong Qin, Jin Dai, Sylvia Chien, Timothy J Martins, Brenda Loera, Quy H Nguyen, Melanie

Authors Victoria H Wu , Bryan S Yung , Farhoud Faraji , Robert Saddawi-Konefka , Zhiyong Wang , Alexander

Wiemers , Sarah Skrzypczyk , Maximillian Hogeweg , Sebastian Bertram , Julia Kurek , Moritz Anft , Timm H

independent investigator integrating the department of Cell Biology at the Centro de Investigación y

medical school and clinical training at Massachusetts General Hospital, Tom joined the laboratory of H. After moving to Rockefeller University with a Howard Hughes Medical Institute appointment, Tom advanced simulations and coarse-grain sampling approaches for membrane proteins in collaborations with Thomas Huber