GPCR Ecosystem is the ultimate resource for expanding your knowledge, making connections, and staying Terry Kenakin Principles of Pharmacology in Drug Discovery I Techniques for Effective Lead Optimization Terry Kenakin Applying Pharmacology to Drug Discovery ​ Watch Dr. Please let us know about this while filling out the registration form. Yes, you can upgrade at any time.

Authors R Mishra, S K Biswas, S Nandi, S Mahajan, K G Sai Balaji, V Gairola, D Poloju, S Gulzar, K P Singh, R K Singh, G K Sharma Tags Genome sequence , Lumpy skin disease , Molecular diversity , Virulence

< GPCR News < GPCRs in Oncology and Immunology Opposite Effects of Src Family Kinases on YAP and ERK combination of insulin and the GPCR agonist neurotensin induced rapid activation of Src family of tyrosine kinases the SFK inhibitors dasatinib, saracatinib, the preferential YES1 inhibitor CH6953755, siRNA-mediated knockdown Surprisingly, our results also demonstrate that exposure to SFK inhibitors, including dasatinib or knockdown of YES and Src induces ERK overactivation in PDAC cells.

Brian Kobilka . Bob doesn’t really need an introduction since his reputation precedes him. I then pressed record, and we chatted for almost 2h about Bob’s career, discoveries, difficulties (yes

Focus on study of drugs and toxins on GPCR (opioid, cannabinoid receptor) and ion channel (K, Ca, TRP

Using the siRNA-mediated knockdown approach, we showed that the stimulatory effect of NPFF on MMP-9 expression Authors Ze Wu , Qiongqiong Jia , Boqun Liu , Lanlan Fang , Peter C K Leung , Jung-Chien Cheng Tags Invasion

Mitochondrial Morphology in Axons Joseph Duman Bai1 Is A Novel Neuronal Substrate Of The Psychiatric Risk Kinase Of The Psychiatric Risk Kinase TNIK Simeon R. Affiliations "Flynn, Helen R.2, Sampedro-Castaneda, Marisol1, Claxton, Suzanne1, Skehel, Mark2, Ultanir, Sila K.1 I then moved to King's College London, where my interest and passion for kinases in brain health and I also work on multiple other kinases in our laboratory implicated in various neurodevelopmental and

Albert Kooistra, Gaspar Pandy-Szekeres September 13, 2021 at 2:00:00 PM Learn More >> CXCR4 heteromers Aaron K. molecules Ross AD Bathgate September 15, 2021 at 9:00:00 PM Learn More >> Profiling of GPCR complexes Kevin Learn More >> FR900359: nature’s weapon and treasure trove for basic and translational research Evi Kostenis

Kevin Pfleger About this episode Dr. I sat down with Kevin to chat about GPCRs, pharmacology, and his contributions to the field in both the Kevin is also Director, Biomedical Innovation at The University of Western Australia (UWA) and the MTPConnect Join me and learn more about Kevin’s work and how he manages all his responsibilities. Dr. Kevin Pfleger on the web LinkedIn ResearchGate Pubmed Google Scholar University of Western Australia

receptor (GPER)/GPR30 forms a complex with the β1-adrenergic receptor, a membrane-associated guanylate kinase (MAGUK) scaffold protein, and protein kinase A anchoring protein (AKAP) 5 in MCF7 breast cancer cells C-terminal tails through which they interact in the plasma membrane with membrane-associated guanylate kinase (MAGUK) scaffold proteins, and in turn protein kinase A anchoring protein (AKAP) 5. Authors Julia Tutzauer , D Stephen Serafin , Tobias Schmidt , Björn Olde , Kathleen M Caron , L M Fredrik

Kathryn E Livingston About Dr. Kathryn E Livingston Dr. Kathryn E Livingston is currently a Product Manager at Gator Bio , a biotechnology company providing Kathryn obtained her BS in Chemistry from Carnegie Mellon University and went on to receive a Ph.D. in Following this, Kathryn did a post-doctoral fellowship at UCSF in the laboratory of Dr. Kathryn E Livingston on the web LinkedIn ResearchGate Pubmed Google Scholar Dr.

< GPCR News < GPCRs in Oncology and Immunology Minireview: functional roles of tissue kallikrein, kinins receptors, and proteases that control tumor progression, such as kallikrein-related peptidases (KLKs In lung cancer to date, evidence indicates that KLK5, KLK6, KLK8, KLK11, and KLK14 are the major peptidases Considering the multiple functions of kinin receptors and KLKs, this review highlights their roles, even , Kallikrein-related peptidases , Kinin receptors , Kinins , Lung cancer , SARS-CoV-2 Source Contribute

Evi Kostenis About Dr. Evi Kostenis "Pharmacist by training - PhD in Pharmacology - Postdoc at the NIH with Dr. Evi Kostenis on the web University of Bonn ResearchGate LinkedIn Dr.

Katarina Nemec About Dr. Katarina Nemec " I am a pharmacist with an interest in systems pharmacology and precision medicine. During my PhD studies in Martin Lohse lab at the Max Delbrueck Center in Berlin, I consolidated my knowledge Katarina Nemec on the web Babu Lab ResearchGate Google Scholar ORCID LinkedIn Twitter Dr.

Terry Kenakin About Dr. Terry Kenakin After obtaining a BSc in chemistry at the University of Alberta Edmonton Canada, Terry Kenakin then moved to the UK, where he did a post-doctoral fellowship in University College London with Kenakin joined Glaxo Inc in RTP where he remained for 25 years through iterations of Glaxo Inc, GlaxoWellcome Terry Kenakin on the web LinkedIn UNC Department of Pharmacology Amazon ResearchGate Pubmed . Dr.

Kari Johnson About this episode Dr. Kari Johnson is currently an assistant professor at the Uniformed Services University of the Health Sciences Kari completed her Ph.D. in Pharmacology at Vanderbilt University before continuing her training as a Join me and learn more about how Kari studies GPCRs in basal ganglia circuits following chronic alcohol Kari Johnson on the web LinkedIn Google Scholar Research Gate USU Twitter Dr.

Kenneth A. Jacobson About Dr. Kenneth A. Jacobson Kenneth A. In 1983, he joined the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) at the Kenneth A. Jacobson on the web NIDDK Web of Science Google Scholar LinkedIn Twitter Dr.

Kaavya Krishna Kumar About Dr. Kaavya Krishna Kumar "I am a postdoc in Prof. Brian Kobilka's lab at Stanford University, USA. Kaavya Krishna Kumar on the web Journal of Biology Chemistry Stanford University Google Scholar LinkedIn

Khaled Abdelrahman About Dr. Khaled Abdelrahman Dr. Khaled Abdelrahman graduated in 2006 with a BSc in Pharmaceutical Sciences from Alexandria University Khaled Abdelrahman on the web Twitter PubMed Google Scholar Dr.

Kathleen Caron About Kathleen M. Caron Kathleen M. Caron, Ph.D. is the Frederik L. Keith Parker to elucidate the role of steroidogenesis in regulating sexual determination and adrenal Kathleen M.

GPCR Podcast << Back to podcast list Sri Kosuri About Dr. Sri Kosuri Sri is a biologist that has helped build technologies, labs, and companies in synthetic biology Sri is originally from New Jersey, Philadelphia, and Kansas and was born in North Carolina. Sri Kosuri on the web Octant ​​​​​​Kosuri Lab ​​​​​​Twitter LinkedIn Dr.

Ilana Kotliar About Dr. Ilana Kotliar "Ilana Kotliar is a postdoctoral associate in the lab of Tom Sakmar at The Rockefeller Ilana Kotliar on the web Google Scholar LinkedIn Twitter Dr.

Aditya Kumar About Dr. G. Aditya Kumar Dr. Aditya Kumar is a postdoctoral fellow at the University of Michigan Medical School. Aditya Kumar on the web University of Michigan Puthenveedu Lab Google Scholar NIH ORCID LinkedIn Twitter

Expression analyses of key enzymes of the glutamate glutamine cycle and the glutamate metabolism indicated /University of Karlsruhe/Institute of Technology (KIT), Germany. His lab is well-known in the research on the cellular function of proteins and their networks related Injection of low-dose ketamine, an antidepressant, can lead to acute (in several hours) and sustained Authors & Affiliations "Groff, Karenna; Donaldson, Hayley; Anderson, Sebastian; Pitti, Kiran; Wang, Shuai

G protein signaling roles of GPR56/ADGRG1 via the characterization of a non-cleavable point mutant knock-in mouse, H381S Frank Kwarcinski Tethered Peptide Activation Mechanism of Adhesion GPCRs Peng Xiao Signaling Szymon P.1, 2, Cechova Kristina3, Bandekar Sumit J.1, 2, Ethan Dintzner1, 2, Leon Katherine1, 2, Dutka We also identified key motifs involved in aGPCR activation. Burruss (Harvard Medical School); Andrew Kruse (Harvard Medical School); Stephen C.

Yuling Feng The ADGRF5/GPR116 receptor is a key regulator of lymphatic endothelial cell identity and Yuling Feng on the web LinkedIn The ADGRF5/GPR116 receptor is a key regulator of lymphatic endothelial Kathleen Caron's laboratory at UNC. Kathryn Defea at the University of California, Riverside. Pal Kasturi on the web Ashoka University < Previous Session Next Session >

Vasiliki1*, Kardinal Ronja2, Jäckstein Michelle3 Yvonne, Kumar Jha Ankush1, Krokidi Sissy Thodou1, Wachten GPR110 is also highly expressed in the kidney, however, little is known about the function of this receptor level in mice devoid of GPR110 gene (GPR110 KO) compared to the wild type (WT). proteins in GPR110 KO and WT mice by label-free LC-MS/MS and pathway analysis. phenotype of albumin urea in GPR110 KO mice.

Authors & Affiliations "Fabian Pohl1, Florian Seufert2, Yin Kwan Chung3, Daniela Volke1, Ralf Hoffmann1 Authors & Affiliations "Garbett, Krassimira, Kordon, Szymon P., Shearer, Tanner, Sando, Richard C.*, Authors & Affiliations "Chung, Yin Kwan2, Pohl, Fabian2, Batebi, Hossein1 Sträter, Norbert3 , Langenhan