Search Results
32 items found for "Yezhong Wang"
- Exploiting frequent and specific expression of PRL3 in pediatric solid tumors for first-in-child use of PRL3-zumab humanized antibody
Abstract "Phosphatase of regenerating liver 3 (PRL3) is a specific tumor antigen overexpressed in a broad range Amos Hong Pheng Loh , Min Thura , Abhishek Gupta , Sheng Hui Tan , Kelvin Kam Yew Kuan , Koon Hwee Ang , Khurshid Merchant , Kenneth Tou En Chang , Hui Yi Yon , Yong Chen , Mathew Hern Wang Cheng , Arjandas
- Comparative Analysis of the GNAI Family Genes in Glioblastoma through Transcriptomics and Single-Cell Technologies
Authors Ahmad Raza , Meng-Chi Yen , Gangga Anuraga , Iram Shahzadi , Muhammad Waqar Mazhar , Hoang Dang Khoa Ta , Do Thi Minh Xuan , Sanskriti Dey , Sachin Kumar , Adrian Wangsawijaya Santoso , Bianca Tobias William , Chih-Yang Wang Tags G-protein-coupled receptor (GPCR) , genome , glioblastoma , malignancy
- Context-dependent ciliary regulation of hedgehog pathway repression in tissue morphogenesis
Authors Sun-Hee Hwang , Kevin Andrew White , Bandarigoda Nipunika Somatilaka , Baolin Wang , Saikat Mukhopadhyay
- Enterococcus-derived tyramine hijacks α2A-adrenergic receptor in intestinal stem cells to exacerbate colitis
Authors Chaoliang Li , Panrui Zhang , Yadong Xie , Shishan Wang , Meng Guo , Xiaowei Wei , Kaiguang Zhang , Dan Cao , Rongbin Zhou , Sheng Wang , Xinyang Song , Shu Zhu , Wen Pan Tags Enterococcus , IBD , ISCs
- Prediction of survival and immunotherapy response by the combined classifier of G protein-coupled receptors and tumor microenvironment in melanoma
Authors Kangjie Shen , Qiangcheng Wang , Lu Wang , Yang Yang , Min Ren , Yanlin Li , Zixu Gao , Shaoluan Zheng , Yiteng Ding , Jiani Ji , Chenlu Wei , Tianyi Zhang , Yu Zhu , Jia Feng , Feng Qin , Yanwen Yang
- SSTR2 positively associates with EGFR and predicts poor prognosis in nasopharyngeal carcinoma
Authors Yue Xu , Zihan Quan , Yuting Zhan , Haihua Wang , Jiadi Luo , Weiyuan Wang , Songqing Fan Tags
- Unbiased multitissue transcriptomic analysis reveals complex neuroendocrine regulatory networks mediated by spinal cord injury-induced immunodeficiency
Authors Hong Zeng , Li Cheng , De-Zhi Lu , Shuai Fan , Ke-Xin Wang , Li-Li Xu , Bin Cai , Mou-Wang Zhou , Jin-Wu Wang Tags Hypothalamo-pituitary-adrenal axis , Neuroendocrine immunomodulatory axis , Neuroinflammation
- Elucidation of active components and target mechanism in Jinqiancao granules for the treatment of prostatitis and benign prostatic hyperplasia
Authors Han Zhou, Tao Hou, Aijin Shen, Wenyi Yu, Liangliang Zhou, Wenjie Yuan, Wanxian Wang, Yumin Yao , Jixia Wang, Yanfang Liu, Xinmiao Liang Tags Benign prostatic hyperplasia , G-protein coupled receptor
- GprC of the nematode-trapping fungus Arthrobotrys flagrans activates mitochondria and reprograms fungal cells for nematode hunting
Authors Xiaodi Hu, David S Hoffmann, Mai Wang, Lars Schuhmacher, Maria C Stroe, Birgit Schreckenberger
- miR-19a may function as a biomarker of oral squamous cell carcinoma (OSCC) by regulating the signaling pathway of miR-19a/GRK6/GPCRs/PKC in a Chinese population
Authors Jijun Chen , Liang Wang , Danhua Ma , He Zhang , Jiayan Fan , Hongyan Gao , Xinyu Xia , Wei Wu
- Purinergic GPCR-integrin interactions drive pancreatic cancer cell invasion
its potential for therapeutic targeting. " Authors Elena Tomas Bort , Megan Daisy Joseph , Qiaoying Wang
- The GPCR-Gαs-PKA signaling axis promotes T cell dysfunction and cancer immunotherapy failure
Authors Victoria H Wu , Bryan S Yung , Farhoud Faraji , Robert Saddawi-Konefka , Zhiyong Wang , Alexander
- Identification of S1PR4 as an immune modulator for favorable prognosis in HNSCC through machine learning
Authors Chenshen Huang , Fengshuo Zhu , Hao Zhang , Ning Wang , Qi Huang Tags Cancer , Machine learning
- Spliceosome mutations are associated with clinical response in a phase 1b/2 study of the PLK1 inhibitor onvansertib in combination with decitabine in relapsed or refractory acute myeloid leukemia
Authors Peter J P Croucher , Maya Ridinger , Pamela S Becker , Tara L Lin , Sandra L Silberman , Eunice S Wang
- Activation of PI3K/Akt pathway by G protein-coupled receptor 37 promotes resistance to cisplatin-induced apoptosis in non-small cell lung cancer
Authors Han Liu , Yingjie Zhu , Huikun Niu , Jing Jie , Shucheng Hua , Xiaoxue Bai , Shuai Wang , Lei
- Ep 44 with Dr. Steven Foord
He introduced molecular pharmacology to a wide range of the company's GPCR projects and was able to initiate
- Ep 30 with Dr. Elva Zhao
run in the mountains, play with Tilly (a 9-year old retired greyhound), collecting mini shoes, and hang
- Increased protease-activated receptor 1 autoantibodies are associated with severe COVID-19
Hoyer , Andreas Glück , Martina Guggeis , Alexander Ossysek , Andre Küller , Derk Frank , Christoph Lange
- AGPCR 24 Session VI
Authors & Affiliations "Groff, Karenna; Donaldson, Hayley; Anderson, Sebastian; Pitti, Kiran; Wang, Shuai
- Ep 33 with Dr. David E. Gloriam
identified physiological hormones of such under characterized ‘orphan’ receptors and functional probes for a range
- CCR6 as a Potential Target for Therapeutic Antibodies for the Treatment of Inflammatory Diseases
Abstract " The CC chemokine receptor 6 (CCR6) is a G protein-coupled receptor (GPCR) involved in a wide range
- CCR7 acts as both a sensor and a sink for CCL19 to coordinate collective leukocyte migration
We further show that these self-generated gradients can sustain the long-range guidance of DCs, adapt
- GPR4 in the pH-dependent migration of melanoma cells in the tumor microenvironment
Migration of GPR4 overexpressing SK-Mel-28 cells was enhanced in a range of pH 6.5 - pH 7.5 as compared
- GPR56 signaling pathway network and its dynamics in the mesenchymal transition of glioblastoma
receptor 56 (GPR56/ADGRG1) is a multifunctional adhesion GPCR involved in diverse biological processes ranging
- NPFF stimulates human ovarian cancer cell invasion by upregulating MMP-9 via ERK1/2 signaling
Authors Ze Wu , Qiongqiong Jia , Boqun Liu , Lanlan Fang , Peter C K Leung , Jung-Chien Cheng Tags Invasion
- G protein-coupled receptors: A target for microbial metabolites and a mechanistic link to microbiome-immune-brain interactions
gut microbiota act as ligands for specific human G protein-coupled receptors (GPCRs) and modulate a range
- Wnt pathway inhibition with the porcupine inhibitor LGK974 decreases trabecular bone but not fibrosis in a murine model with fibrotic bone
Authors Hsuan Lung, Kelly L Wentworth, Tania Moody, Ariane Zamarioli, Apsara Ram, Gauri Ganesh, Misun Kang
- Principles of Pharmacology in Drug Discovery I
of how pharmacology can greatly extend the ability to predict a candidate's therapeutic value in a range