Search Results
74 items found for "Yong Chen"
- Exploiting frequent and specific expression of PRL3 in pediatric solid tumors for first-in-child use of PRL3-zumab humanized antibody
A 28.6% reduction in maximum target lesion diameter was achieved when PRL3-zumab was administered concurrently Authors Amos Hong Pheng Loh , Min Thura , Abhishek Gupta , Sheng Hui Tan , Kelvin Kam Yew Kuan , Koon Hwee Ang , Khurshid Merchant , Kenneth Tou En Chang , Hui Yi Yon , Yong Chen , Mathew Hern Wang Cheng
- GPCR signaling contributes to immune characteristics of microenvironment and process of EBV-induced lymphomagenesis
Authors Jie Xiong , Yu-Ting Dai , Wen-Fang Wang , Hao Zhang , Chao-Fu Wang , Tong Yin , Shu Cheng , Hui-Juan Zhong , Shan-He Yu , Lu Jiang , Sheng-Yue Wang , Hai Fang , Rui-Hong Zhang , Yue Zhu , Hong-Mei Yi , Xu-Feng Jiang , Jia-Yi Chen , Li Wang , Peng-Peng Xu , Sai-Juan Chen , Wei-Li Zhao Tags CCR1 , Epstein-Barr
- Session VIII * | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
The GAIN Domain Tobias Langenhan Characterization of Phenotypes Associated with GPR110 Deletion Hee-Yong on the web Langenhan Lab LinkedIn Characterization of Phenotypes Associated with GPR110 Deletion Hee-Yong , National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, USA" About Hee-Yong Kim "Senior Investigator and Chief of the Laboratory of Molecular Signaling at NIAAA, NIH" Hee-Yong
- Regulator of G protein signaling 16 restrains apoptosis in colorectal cancer through disrupting TRAF6-TAB2-TAK1-JNK/p38 MAPK signaling
Authors Hao Shen, Jie Yuan, Dafeng Tong, Bingchen Chen, Enda Yu, Guanglei Chen, Cheng Peng, Wenjun Chang
- Deciphering a GPCR-lncRNA-miRNA Nexus: Identification of an Aberrant Therapeutic Target in Ovarian Cancer
earlier transcriptomic analysis identified Urothelial Carcinoma Associated-1 (UCA1) as an LPA-stimulated long Srishti Kashyap , Kar-Ming Fung , Chao Xu , Resham Bhattacharya , Priyabrata Mukherjee , Ciro Isidoro , Yong Sang Song , Danny N Dhanasekaran Tags GPCR , High Grade Serous Ovarian Carcinoma , Let-7 miRNAs , Oncogenic
- The β2-adrenergic receptor associates with CXCR4 multimers in human cancer cells
Authors Junyi Liang , Mohamed Seghiri , Pradeep Kumar Singh , Hyeon Gyu Seo , Ji Yeong Lee , Yoonjung Jo , Yong Bhum Song , Chulo Park , Piotr Zalicki , Jae-Yeon Jeong , Won-Ki Huh , Niña G Caculitan ,
- A GPCR-neuropeptide axis dampens hyperactive neutrophils by promoting an alternative-like polarization during bacterial infection
Authors Naina Gour , Hwan Mee Yong , Aishwarya Magesh , Aishwarya Atakkatan , Felipe Andrade , Stephane Lajoie , Xinzhong Dong Tags IFNγ , Mrgpra1 GPCR , NPFF , lung infection , neuropeptide FF , neutrophil
- Small-molecule targeting of GPCR-independent noncanonical G-protein signaling in cancer
Zhao , Vincent DiGiacomo , Mariola Ferreras-Gutierrez , Shiva Dastjerdi , Alain Ibáñez de Opakua , Jong-Chan Park , Alex Luebbers , Qingyan Chen , Aaron Beeler , Francisco J Blanco , Mikel Garcia-Marcos .
- Full Agenda for Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Kordon · Tingzhen Shen · Bill Huang · Júlia Rosell · Sheila Ribalta-Mena · Mariam Melkumyan Read More Zozaya Read More 11:30 AM Session VIII Physiological and pathological roles of AGPCRs in the periphery Cheng-Chih pathological roles of AGPCRs in the periphery Tobias Langenhan · Anastasia Georgiadi · Douglas Tilley · Hee-Yong Identity Andrew Dates Heterogeneity of Tethered Agonist Signaling in Adhesion G Protein-Coupled Receptors Cheng-Chih CD97 in glioblastoma Florian Seufert Unveiling the GPS Cleavage Mechanism in ADGRL1 with QM/MM Hee-Yong
- Noval insights and therapeutic strategies for tumor-induced kidney pathologies
Authors Meng Wang, Yong Han, Chao Zhang Source Contribute to the GPCR News Coming soon Become a Contributor
- GPR143 controls ESCRT-dependent exosome biogenesis and promotes cancer metastasis
promote cancer cell motility. " Authors Yu Jin Lee , Kyeong Jin Shin , Hyun-Jun Jang , Jin-Sun Ryu , Chae Young Lee , Jong Hyuk Yoon , Jeong Kon Seo , Sabin Park , Semin Lee , A Reum Je , Yang Hoon Huh , Sun-Young Kong , Taejoon Kwon , Pann-Ghill Suh , Young Chan Chae Tags GPR143 , HRS , MVB , breast cancer , exosomal
- Regulator of G protein signaling protein 6 alleviates acute lung injury by inhibiting inflammation and promoting cell self-renewal in mice
Authors Juan Song , Miao Li , Cuicui Chen , Jian Zhou , Linlin Wang , Yu Yan , Jun She , Lin Tong , Yuanlin Song Tags Acute lung injury , Apoptosis , Cell-renewal , Inflammation , Regulator of G protein signaling
- PAXIP1-AS1 is associated with immune infiltration and predicts poor prognosis in ovarian cancer
infiltration and predicts poor prognosis in ovarian cancer Published date August 15, 2023 Abstract "The long Authors Buze Chen , Xiaoyuan Lu , Qingmei Zhou , Qing Chen , Siyan Zhu , Guilin Li , Hui Liu Source Contribute
- Exacerbating effects of single-dose acute ethanol exposure on neuroinflammation and amelioration by GPR110 (ADGRF1) activation
Authors Sharmistha Banerjee , Taeyeop Park , Yoo Sun Kim , Hee-Yong Kim Tags Adenylyl cyclase , Cytokines
- Session VIII | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
of AGPCRs in the periphery ADGRG1/GPR56 regulates survival of terminally differentiated CD8+ T cells Cheng-Chih and disease Douglas Tilley ADGRG1/GPR56 regulates survival of terminally differentiated CD8+ T cells Cheng-Chih Hsiao Abstract Only available for AGPCR 24 Attendees Authors & Affiliations "Cheng-Chih Hsiao1,2, Hendrik Departments of Neurology and Immunology, Erasmus Medical Center, Rotterdam, The Netherlands" About Cheng-Chih Netherlands Institute for Neuroscience; 2022 - present: Researcher associate, Netherlands Brain Bank" Cheng-Chih
- Molecular docking and dynamics simulation studies uncover the host-pathogen protein-protein interactions in Penaeus vannamei and Vibrio parahaemolyticus
type III secretion apparatus protein), Complex 2 (Protein kinase domain-containing protein-Chemotaxis CheY protein), and Complex 3 (GPCR-Chemotaxis CheY protein) was found to interact with -4319.76, -5271.39 Muhamad Arif Mohamad Jamali , Siti Aishah Sufira , Khor Waiho , Hanafiah Fazhan , Noraznawati Ismail , Yeong
- Itaconate in host inflammation and defense
Authors Dan Ye , Pu Wang , Lei-Lei Chen , Kun-Liang Guan , Yue Xiong Tags IRG1/ACOD1 , cancer , inflammatory
- Ep 50 with Dr. Thomas P. Sakmar
This work involved active long-term collaborators, including Richard Mathies and Fritz Siebert , and functional micro-domains” and the “helix movement model of receptor activation” were confirmed later when Recently, Tom’s lab discovered, along with Yu Chen and Ping Chi , that a mutant of CYSLTR2 is a driver
- miR-19a may function as a biomarker of oral squamous cell carcinoma (OSCC) by regulating the signaling pathway of miR-19a/GRK6/GPCRs/PKC in a Chinese population
Authors Jijun Chen , Liang Wang , Danhua Ma , He Zhang , Jiayan Fan , Hongyan Gao , Xinyu Xia , Wei Wu
- TIPE proteins control directed migration of human T cells by directing GPCR and lipid second messenger signaling
Authors Jiyeon Yu , Ali Zamani , Jason R Goldsmith , Zienab Etwebi , Chin Nien Lee , Youhai H Chen ,
- Activation of orphan receptor GPR132 induces cell differentiation in acute myeloid leukemia
Authors Chunyang Yi, Jiacheng He, Dan Huang, Yumiao Zhao, Chan Zhang, Xiyun Ye, Ying Huang, Ruth Nussinov
- Posters | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Kordon Deorphanization Of The Adhesion GPCRs GPR110 and GPR116 Tingzhen Shen Self-Cleavage of GPR110 the web Araç Laboratory at UChicago Deorphanization Of The Adhesion GPCRs GPR110 and GPR116 Tingzhen Shen Tingzhen Shen on the web University of Michigan Self-Cleavage of GPR110 SEA Domain and Its Impact on Autoproteolysis Bill Huang Abstract Only available for AGPCR 24 Workshop Attendees Authors & Affiliations "Hee-Yong consequences associated with the GPR110 receptor. " Authors & Affiliations "Joel Toro, Bill Huang, Hee-Yong
- GPR37 expression as a prognostic marker in gliomas: a bioinformatics-based analysis
Authors Kairong Liang , Zhaoxiong Guo , Shizhen Zhang , Danmin Chen , Renheng Zou , Yuhao Weng , Chengxiang
- Exploration of prognostic and treatment markers in hepatocellular carcinoma via GPCR-related genes analysis
Authors Yuxin Wang , Bao Jin , Xiangan Wu , Jiali Xing , Baoluhe Zhang , Xiaokun Chen , Xiao Liu , Xueshuai
- Unbiased multitissue transcriptomic analysis reveals complex neuroendocrine regulatory networks mediated by spinal cord injury-induced immunodeficiency
Authors Hong Zeng , Li Cheng , De-Zhi Lu , Shuai Fan , Ke-Xin Wang , Li-Li Xu , Bin Cai , Mou-Wang Zhou
- NPFF stimulates human ovarian cancer cell invasion by upregulating MMP-9 via ERK1/2 signaling
Authors Ze Wu , Qiongqiong Jia , Boqun Liu , Lanlan Fang , Peter C K Leung , Jung-Chien Cheng Tags Invasion
- LPA1-mediated inhibition of CXCR4 attenuates CXCL12-induced signaling and cell migration
Authors Jong Min Hong , Jin-Woo Lee , Dong-Seung Seen , Jae-Yeon Jeong , Won-Ki Huh Tags Cancer , Chemokine
- GPR97 depletion aggravates imiquimod-induced psoriasis pathogenesis via amplifying IL-23/IL-17 axis signal pathway
Authors Yaoxin Gao, Weirong Zhan, Dandan Guo, Haizhen Lin, Muhammad Asad Farooq, Chenxu Jin, Li Zhang , Ying Zhou, Jie Yao, Yixin Duan, Cong He, Shuai Jiang, Wenzheng Jiang Tags DCs , GPR97 , Keratinocytes