studies show that β-arrestin1 drives tauopathy by destabilizing microtubules and impeding p62/SQSTM1 autophagy

for complete autophagy. Inhibition of autophagy by 3-methyladenine or interference of ATG5 or ATG7 attenuated HBx-induced cell The absence of autophagy abolished the phosphorylation of CDK2 and the activity of the CDK2-CCNE1 complex Our results demonstrate that ARRB1 plays a critical role in HBV-related HCC via modulating autophagy related 5; ATG7: autophagy related 7; Baf A1: bafilomycin A1; CDK2: cyclin dependent kinase 2; CDKN1B

taste receptor agonists attenuate macrophage IL‐1β expression and eosinophilic inflammation linked to autophagy Autophagy deficiency in myeloid cells plays a causal role in eosinophilic CRS (ECRS) via macrophage IL ‐1β overproduction, thereby suggesting autophagy regulation as a potential therapeutic modality. Trehalose is a disaccharide sugar with known pro‐autophagy activity and effective in alleviating diverse We sought to investigate the therapeutic potential of autophagy‐enhancing agent, trehalose, or related

mTOR) senses upstream stimuli to regulate numerous cellular functions such as metabolism, growth, and autophagy

Receptor Deciphering the role of glycosaminoglycans in GPCR signaling G protein-coupled receptor-mediated autophagy

identification of a G protein-biased allosteric modulator of cannabinoid receptor CB1 GPCR function in autophagy

circuits GPCRs in Oncology and Immunology RGS20 promotes non-small cell lung carcinoma proliferation via autophagy

High expression of GPR50 promotes the proliferation, migration and autophagy of hepatocellular carcinoma

and Signaling Butyrate induces STAT3/HIF-1α/IL-22 signaling via GPCR and HDAC3 inhibition to activate autophagy

astrocytes for Parkinson's disease therapy: unraveling the Foxg1-mediated neuroprotective mechanism through autophagy-mediated

β-arrestins and its potential role in heart failure GPCRs in Neuroscience Role of lipids in the control of autophagy

The adhesion G-protein-coupled receptor VLGR1/ADGRV1 controls autophagy.

and Immunology GPR176 Promotes Cancer Progression by Interacting with G Protein GNAS to Restrain Cell Mitophagy