of Technology in Genova, Italy (2008-2016) and an Associate Research Professor in the Department of Cell Biology at Duke University in North Carolina, USA (1996-2008). Before joining the Department of Cell Biology in 1996 as a postdoc and becoming faculty at Duke in 2000 As of August 2022, he has over 270 publications in scientific journals (including Science, Nature, Cell

Cardarelli is a drug development leader with extensive experience driving drug discovery teams in bringing biologics She has expertise in cell biology, pharmacology, translational medicine, oncology, immuno-oncology, immunology Previously, she held the position of Vice President of Cell Biology & Pharmacology, at Bristol-Myers She has extensive experience working with Biologics, and Antibody Drug Conjugates as well as experience

Beatriz Blanco Redondo The Adhesion GPCR Latrophilin Interacts With The Notch Pathway To Control Germ Cell Johannisallee 30, 04103 Leipzig, Germany 2Laboratory of Neurovascular Signaling, Department of Molecular Biology Biology, Department of Biology, Heinrich Heine University Düsseldorf, Düsseldorf, Germany 2 Rudolf Schönheimer Biology at Heinrich Heine University in Düsseldorf, Germany. Willem Berend Post on the web Cell Biology LinkedIn < Previous Session Next Session >

Eldridge Distinguished Professor and Chair of the Department of Cell Biology & Physiology at The University Caron received a BS in Biology and BA in Philosophy at Emory University and a PhD at Duke University special emphasis on G protein coupled receptors and receptor activity modifying proteins in vascular biology Kathleen Caron on the web UNC-Chapel Hill Department of Cell Biology and Physiology UNC Lineberger Comprehensive

Fan is currently an associate professor of Pharmacology and Pathology and Cell Biology at Columbia University Qing is a structural biologist interested in the molecular mechanisms controlling how class C GPCRs transmit

News < GPCRs in Oncology and Immunology Purinergic GPCR-integrin interactions drive pancreatic cancer cell P2RY2 presents as the purinergic gene with the strongest association with hypoxia, the highest cancer cell-specific receptor-integrin interactions were required for effective downstream signalling, leading to cancer cell Samadi , Hemant M Kocher , Sabrina Simoncelli , Peter J McCormick , Richard Philip Grose Tags cancer biology , cell biology , human.

employed by these atypical 7-transmembrane receptors, combining biochemical and structural approaches with cell biology and in vivo models. GPCR signaling pathways that operate within the primary cilium, a tiny antenna-shaped structure at the cell

Sudha Shenoy is currently an Associate Professor in Medicine & Cell Biology in the Division of Cardiovascular

Eldridge Distinguished Professor and Chair of the Department of Cell Biology & Physiology at The University Caron received a BS in Biology and BA in Philosophy at Emory University and a PhD at Duke University special emphasis on G protein coupled receptors and receptor activity modifying proteins in vascular biology

Lauren Slosky About Irfan Dhanidina "My interest in oncology research led me to pursue a BSc in Biology Eldridge Distinguished Professor and Chair of the Department of Cell Biology & Physiology at The University Caron received a BS in Biology and BA in Philosophy at Emory University and a PhD at Duke University Kathleen Caron on the web UNC-Chapel Hill Department of Cell Biology and Physiology UNC Lineberger Comprehensive Integrating GPCR biology, behavioral pharmacology, and systems neuroscience approaches, the Slosky Lab

I completed my Ph.D. in molecular and cell biology at UConn and then joined Addgene as a Quality Control

Stephen, Caron Kathleen M Department of Cell Biology and Physiology at UNC Chapel Hill 111 Mason Farm Van Meir’s research examines how genetic alterations and hypoxia induce changes in cell biology that To address these gaps in knowledge, we used biochemical and cell-biological approaches using cell-lines : Department of Biology, Ashoka University. Currently: University of Leipzig Mansi Tiwari: Department of Biology, Ashoka University.

author, presenter) Kohlenbach LM -2 Zhou Y -1 Marugan JJ -3 Barak LS -1 (senior author) 1-Department of Cell Biology, Duke University Medical Center, Durham, NC 27710. 2-Department of Biology, Duke Trinity College

Simone Prömel Simone Prömel is currently a professor of cell biology at the Heinrich Heine University of action of Adhesion GPCRs and found that they do not only mediate classical G protein signals into cells

roles of AGPCRs in the periphery ADGRG1/GPR56 regulates survival of terminally differentiated CD8+ T cells health and disease Douglas Tilley ADGRG1/GPR56 regulates survival of terminally differentiated CD8+ T cells Centre for Experimental Medicine, Institute for Biocehmistry and Molecular Cell Biology, University Medical Cancer, Helmholtz Diabetes Centre, Munich 2015 - 2018 Postdoctoral fellow, Department of Adipose Tissue Biology and Molecular Biology, Karolinska Institute, Sweden" Anastasia Georgiadi on the web Endocrine Pharmacology

moved to Mexico City to establish himself as an independent investigator integrating the department of Cell Biology at the Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional (Cinvestav-IPN as various alternatively spliced isoforms thus potentially resulting in differential modulation of cell

Vanderbilt University, Nashville, TN 37232, USA 4 Peking University, China 5 Department of Anatomy and Cell Biology, University of Illinois at Chicago, Chicago, IL 60612, USA. She oversaw an increase of the size of the Department, as well as a quintupling of its NIH funding, in transduction and neuroscience, and she has expanded it in the areas of drug discovery and structural biology Stanley Cohen Award “For Research Bringing Diverse Disciplines, such as Chemistry or Physics, to Solving Biology

developed expertise over the past two decades studying structure/function relationships of GPCRs using live-cell Her work focused on chemokine receptors, members of the GPCR family that control cell movement in the Monserrat Avila Zozaya I did a PhD in cell biology at CINVESTAV, Mexico. About John Azietaku John Teye Azietaku,PhD is a trained pharmacist, holding a Ph.D. in Drug Discovery Biology

Under nutrient depletion, the model choanoflagellate Salpingoeca rosetta forms distinct cell types that We found that the knock-out of cupidon induces a gain in cell adhesion and cell fusion, resembling the mating behavior of wild-type cells under nutrient depletion. Cupidon mutants, similar to starved wild-type cells, upregulate various extracellular matrix-related Biology, University of California Berkeley" About Alain Garcia De Las Bayonas "Hi everyone!

developmental biologist with a focus on how planar cell polarity drives complex tissue morphogenesis Jianxiang Xue "I am a postdoctoral researcher working in the Department of Biochemistry and Molecular Biology Department of Biochemistry and Molecular Biology, The University of Chicago, Chicago, IL, USA; 2. Current affiliation: Department of Structural Biology, Genentech, South San Francisco, CA, USA" About Biology PhD student " Sheila Ribalta-Mena on the web CINVESTAV ResearchGate LinkedIn GPR110 modulates

Registration Logo Contest Committee Sponsors GPCR Retreat Program < Back to schedule Interaction with the cell adhesion molecule NEGR1 affects mGluR5 cell signalling Date & Time Friday, November 3rd / 1:30 PM Abstract Ribeiro has supervised eleven M.Sc. and six Ph.D. students, as well as five post-doctorate fellows. Nowadays, her research group comprises four undergraduates, two M.Sc., and six Ph.D. students, as well These drugs were shown to be very effective to rescue the cell death observed in a mouse model of Huntington

combination of brentuximab vedotin and chidamide synergistically suppresses the proliferation of T-cell lymphoma cells through the enhancement of apoptosis Published date November 3, 2023 Abstract " Purpose : Peripheral T-cell lymphoma (PTCL) is an aggressive disease with a poor prognosis. HH cells, originating from an aggressive cutaneous T-cell lymphoma, were used as an experimental model The combined effects of chidamide and BV were demonstrated in a study of HH-cell xenograft mice; mean

types (neutrophils, T cells, B cells and dendritic cells) and systematically addressed the functional consequences on GPCR-controlled cell migration and tissue localization. Combined depletion of GRK2 and GRK6 in T cells and B cells shows distinct functional outcomes for (a) one GPCR type in different cell types, and (b) different GPCRs in one cell type. ; GRK; T cells; dendritic cells; immune cell trafficking; leukocytes; neutrophils.

< GPCR News < GPCRs in Oncology and Immunology Molecular characterization of breast cancer cell pools to control T-47D cells. More than 6000 genes were DE in control T-47D cells upon stimulation with P4 or P4 plus E2. GO analysis revealed seven significantly enriched biological processes affected by PR and associated Many of the genes affected by PR are part of central biological processes of tumorigenesis."

Metallo-protease Peptidase M84 from Bacillusaltitudinis induces ROS-dependent apoptosis in ovarian cancer cells This metallo-protease had no discernible impact on normal cell survival, but it specifically induced apoptosis in ovarian cancer cells. This evoked apoptotic death of the ovarian cancer cells through the intrinsic route. Das, Elizabeth Mahapatra, Saibal Saha, Ananda Pal, Parash Prasad, Amit Pal Tags Cancer , Molecular biology

and Immunology Dynamic Phosphoproteomics of BRS3 Activation Reveals the Hippo Signaling Pathway for Cell receptor (GPCR) that is involved in a variety of pathological and physiological processes, while its biological The lung cancer cell line H1299-BRS3 was treated with MK-5046, an agonist of BRS3, for different durations dephosphorylation and nucleus localization of the Yes-associated protein (YAP), and its association with cell Our data collectively demonstrate that BRS3 activation contributes to cell migration through downregulation

progression in MCF-7 cells Published date March 1, 2024 Abstract "Vasoactive intestinal peptide (VIP In this study, we examined the role of VIPR2 in cell cycle progression. in MCF-7 cells. The percentage of cells in the S-M phase was decreased in MCF-7 cells treated with KS-133. In MCF-7 cells stably-expressing VIPR2, KS-133 decreased PI3K activity and cAMP levels.

News < GPCRs in Oncology and Immunology Respiratory infections predominate after day 100 following B-cell maturation antigen-directed CAR T-cell therapy Published date September 26, 2023 Abstract "Infections are an important complication after B-cell maturation antigen (BCMA)-directed chimeric antigen receptor (CAR) T-cell therapy and risks may differ between the early and late periods. Respiratory infections predominate after BCMA CAR T-cell therapy, particularly after day 100.