October 2022 GPR15 expressed in T lymphocytes from RA patients is involved in leukocyte chemotaxis to

focus is currently being directed towards CXCR1/2 inhibitors, as these receptors primarily induce the chemotaxis

focus is currently being directed towards CXCR1/2 inhibitors, as these receptors primarily induce the chemotaxis

Immunology G Protein-coupled Receptor-mediated Membrane Targeting of PLCγ2 is Essential for Neutrophil Chemotaxis GPCR-mediated phospholipase C (PLC) signaling and is essential for neutrophil polarization and migration during chemotaxis dynamics of actin polymerization; and consequently, defects in cell polarization and migration during chemotaxis targeting of PLCγ2 and the signaling pathways by which PLCγ2 plays an essential role in neutrophil chemotaxis Tags G protein-coupled receptor (GPCR) , calcium-promoted Ras inactivator (CAPRI) , chemotaxis , neutrophils

carboxyterminal truncation of human CXCL10 attenuates glycosaminoglycan binding, CXCR3A signaling and lymphocyte chemotaxis Interferon-γ-inducible protein of 10 kDa (IP-10/CXCL10) is a dual-function CXC chemokine that coordinates chemotaxis Furthermore, CXCL10(1-73) incited significantly less primary human T lymphocyte chemotaxis in vitro and residues Lys74-Pro77 of CXCL10 are important for GAG binding, signaling through CXCR3A, T lymphocyte chemotaxis

Oncology and Immunology GPR15 expressed in T lymphocytes from RA patients is involved in leukocyte chemotaxis Tags C10ORF99; GPR15; GPR15L; T lymphocytes; chemotaxis; rheumatoid arthritis; synovium.