humanized antibody Activation of PI3K/Akt pathway by G protein-coupled receptor 37 promotes resistance to cisplatin-induced

and Immunology Activation of PI3K/Akt pathway by G protein-coupled receptor 37 promotes resistance to cisplatin-induced Most importantly, we investigated whether GPR37 affects cisplatin-induced drug resistance in NSCLC. NSCLC cell invasion, migration, and proliferation, suppresses cell apoptosis, heightens resistance to cisplatin NSCLC cell invasion, migration, and proliferation, promotes cell apoptosis, increases sensitivity to cisplatin , Shucheng Hua , Xiaoxue Bai , Shuai Wang , Lei Song Tags EMT , GPR37 , NSCLC , PI3K/Akt pathway , cisplatin

More significantly, intratumoral delivery of UCA1-specific siRNAs inhibits the growth of cisplatin-refractory