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August 2022 "Epithelial tube formation requires Rho1-dependent actomyosin contractility to generate the We also report on unexpected Fog-independent roles for Smog in maintaining epithelial integrity and organizing wherein Smog regulates distinct myosin pools and actin cytoskeleton in a ligand-dependent manner during epithelial

September 2022 "Epithelial tube formation requires Rho1-dependent actomyosin contractility to generate We also report on unexpected Fog-independent roles for Smog in maintaining epithelial integrity and organizing wherein Smog regulates distinct myosin pools and actin cytoskeleton in a ligand-dependent manner during epithelial

pathophysiology is not fully understood, but the working hypothesis postulates that a combination of epithelial However, in epithelial cells, OGR1 promotes epithelial to mesenchymal transition (EMT) and inflammation

is an autocleavable adhesion GPCR that traffics with Dlg1 to the basolateral membrane and regulates epithelial Here, we show that human GPR125 likely undergoes cis-autoproteolysis when expressed in canine kidney epithelial GPR125, an autocleavable adhesion GPCR, appears to play a crucial role in apicobasal polarization in epithelial

Here, we discovered that the epithelial-cell-derived antimicrobial peptides defensins activated orphan This study demonstrated the importance of epithelial-neutrophil signaling via the defensin-Mrgpra2 axis

a key transducer of the hedgehog (HH) morphogen, which plays an essential role in the patterning of epithelial Here, we examine how HH controls SMO subcellular localization and activity in a polarized epithelium

2022 Microbial Metabolites Orchestrate a Distinct Multi-Tiered Regulatory Network in the Intestinal Epithelium That Directs P-Glycoprotein Expression "P-glycoprotein (P-gp) is a key component of the intestinal epithelium RNA sequencing of intestinal epithelial cells responding to butyrate and secondary bile acids in combination

Uterine Corpus Endometrial Carcinoma (UCEC) isa malignanttumorofendometrium epithelial, whichis alsooneofthemostcommonfemalereproductivesystemtumors

In vitro, we used IFNα to stimulate human salivary gland epithelial cells (HSGECs), and the results showed signaling is involved in the pathogenesis of pSS and that β-arrestin2 encourages inflammation-induced epithelial

, the channel is expressed in various tissues and cell types including neurons as well as glial and epithelial

pregnancy, the mammary gland (MG) undergoes remodeling, which involves alveolar differentiation of mammary epithelial

receptors (PAR), a subgroup of GPCRs, form a family of four members (PAR1-4) centrally involved in epithelial

MDA-MB-231 cells are metastatic when implanted in mice while BT-20 are not and remain epithelial-like

Drugs, and more Selenomethionine Promotes Milk Protein and Fat Synthesis and Proliferation of Mammary Epithelial

analysis uncover GPR183 as a key mediator for methionine to stimulate milk synthesis in mouse mammary epithelial

Comparison of the Genomic Activity of an EP4-Receptor and β2-Adrenoceptor Agonist in BEAS-2B Human Bronchial Epithelial

mediated non-canonical pathway GPCR Screening Reveals that the Metabolite Receptor HCAR3 Regulates Epithelial

FFAR4 improves the senescence of tubular epithelial cells by AMPK/SirT3 signaling in acute kidney injury

GPCR Activation and Signaling GPCR screening reveals that the metabolite receptor HCAR3 regulates epithelial

Receptor, GPR3 After wounding, a G-protein coupled receptor promotes the restoration of tension in epithelial

phosphorylation After wounding, a G-protein coupled receptor promotes the restoration of tension in epithelial

OR51E2, initially assumed to be GPCRs only expressed in prostate tissue, play a role in prostate cancer epithelial