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22 items found for "epithelial"
- Multifunctional role of GPCR signaling in epithelial tube formation
August 2022 "Epithelial tube formation requires Rho1-dependent actomyosin contractility to generate the We also report on unexpected Fog-independent roles for Smog in maintaining epithelial integrity and organizing wherein Smog regulates distinct myosin pools and actin cytoskeleton in a ligand-dependent manner during epithelial
- Multifunctional role of GPCR signaling in epithelial tube formation
September 2022 "Epithelial tube formation requires Rho1-dependent actomyosin contractility to generate We also report on unexpected Fog-independent roles for Smog in maintaining epithelial integrity and organizing wherein Smog regulates distinct myosin pools and actin cytoskeleton in a ligand-dependent manner during epithelial
- Cell-Type-Specific Effects of the Ovarian Cancer G-Protein Coupled Receptor (OGR1) on Inflammation..
pathophysiology is not fully understood, but the working hypothesis postulates that a combination of epithelial However, in epithelial cells, OGR1 promotes epithelial to mesenchymal transition (EMT) and inflammation
- GPR125 (ADGRA3) is an autocleavable adhesion GPCR that traffics with Dlg1 to the basolateral...
is an autocleavable adhesion GPCR that traffics with Dlg1 to the basolateral membrane and regulates epithelial Here, we show that human GPR125 likely undergoes cis-autoproteolysis when expressed in canine kidney epithelial GPR125, an autocleavable adhesion GPCR, appears to play a crucial role in apicobasal polarization in epithelial
- Keratinocyte-derived defensins activate neutrophil-specific receptors Mrgpra2a/b to prevent skin...
Here, we discovered that the epithelial-cell-derived antimicrobial peptides defensins activated orphan This study demonstrated the importance of epithelial-neutrophil signaling via the defensin-Mrgpra2 axis
- High hedgehog signaling is transduced by a multikinase-dependent switch controlling the...
a key transducer of the hedgehog (HH) morphogen, which plays an essential role in the patterning of epithelial Here, we examine how HH controls SMO subcellular localization and activity in a polarized epithelium
- Microbial Metabolites Orchestrate a Distinct Multi-Tiered Regulatory Network in the Intestinal Epith
2022 Microbial Metabolites Orchestrate a Distinct Multi-Tiered Regulatory Network in the Intestinal Epithelium That Directs P-Glycoprotein Expression "P-glycoprotein (P-gp) is a key component of the intestinal epithelium RNA sequencing of intestinal epithelial cells responding to butyrate and secondary bile acids in combination
- A correlation study of adhesion G protein-coupled receptors as potential therapeutic targets in...
Uterine Corpus Endometrial Carcinoma (UCEC) isa malignanttumorofendometrium epithelial, whichis alsooneofthemostcommonfemalereproductivesystemtumors
- Deficiency of β-arrestin2 alleviates apoptosis through GRP78-ATF6-CHOP signaling pathway in ...
In vitro, we used IFNα to stimulate human salivary gland epithelial cells (HSGECs), and the results showed signaling is involved in the pathogenesis of pSS and that β-arrestin2 encourages inflammation-induced epithelial
- TRPM3 in the eye and in the nervous system - from new findings to novel mechanisms
, the channel is expressed in various tissues and cell types including neurons as well as glial and epithelial
- Effect Delta-9-tetrahydrocannabinol and cannabidiol on milk proteins and lipid levels in HC11 cells
pregnancy, the mammary gland (MG) undergoes remodeling, which involves alveolar differentiation of mammary epithelial
- PH-Binding Motif in PAR4 Oncogene: From Molecular Mechanism to Drug Design
receptors (PAR), a subgroup of GPCRs, form a family of four members (PAR1-4) centrally involved in epithelial
- Lack of Oestrogen Receptor Expression in Breast Cancer Cells Does Not Correlate with Kisspeptin...
MDA-MB-231 cells are metastatic when implanted in mice while BT-20 are not and remain epithelial-like
- 📢 GPCR Update: August 19-25, 2024 | Thrilling Announcement: New Pharmacology Course Dates & Exclusive Discounts Inside!
Drugs, and more Selenomethionine Promotes Milk Protein and Fat Synthesis and Proliferation of Mammary Epithelial
- 📰 GPCR Weekly News, June 3 to June 9, 2024
analysis uncover GPR183 as a key mediator for methionine to stimulate milk synthesis in mouse mammary epithelial
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Comparison of the Genomic Activity of an EP4-Receptor and β2-Adrenoceptor Agonist in BEAS-2B Human Bronchial Epithelial
- 📰 GPCR Weekly News, May 27 to June 2, 2024
mediated non-canonical pathway GPCR Screening Reveals that the Metabolite Receptor HCAR3 Regulates Epithelial
- 📰 GPCR Weekly News
FFAR4 improves the senescence of tubular epithelial cells by AMPK/SirT3 signaling in acute kidney injury
- 📰 GPCR Weekly News, December 11 to 17, 2023
GPCR Activation and Signaling GPCR screening reveals that the metabolite receptor HCAR3 regulates epithelial
- 📰 GPCR Weekly News, February 19 to 25, 2024
Receptor, GPR3 After wounding, a G-protein coupled receptor promotes the restoration of tension in epithelial
- 📰 GPCR Weekly News, March 25 to March 31, 2024
phosphorylation After wounding, a G-protein coupled receptor promotes the restoration of tension in epithelial
- Odorant receptors – a bit of smell for drug discovery
OR51E2, initially assumed to be GPCRs only expressed in prostate tissue, play a role in prostate cancer epithelial