Ecosystem
Beta Site
Search Results
15 items found for "epithelial"
- Coronavirus Porcine Epidemic Diarrhea Virus Utilizes Chemokine Interleukin-8 to Facilitate Viral Replication by Regulating Ca2+ Flux
Viral Replication by Regulating Ca2+ Flux Published date May 29, 2023 Abstract "Chemokine production by epithelial However, the effect of chemokine on epithelia and how chemokine is involved in coronavirus infection promote coronavirus porcine epidemic diarrhea virus (PEDV) infection in African green monkey kidney epithelial cells (Vero) and Lilly Laboratories cell-porcine kidney 1 epithelial cells (LLC-PK1). This study evaluated the effect of IL-8 on PEDV infection in epithelia.
- Enterococcus-derived tyramine hijacks α2A-adrenergic receptor in intestinal stem cells to exacerbate colitis
Using an engineered tyrDC-deficient Enterococcus faecalis strain and intestinal epithelial cell-specific knockout mice, we show that Enterococcus-derived tyramine suppresses ISC proliferation, thereby impairing epithelial
- Ascitic Shear Stress Activates GPCRs and Downregulates Mucin 15 to Promote OvarianCancer Malignancy
shear stresses display heightened G protein-coupled receptor mechanosignaling and the induction of an epithelial DiFeo, David Nordsletten Tags G-protein coupled receptors (GPCR) , NF-κB , PLCβ , ascitic currents , epithelial
- Regulator of G protein signaling protein 6 alleviates acute lung injury by inhibiting inflammation and promoting cell self-renewal in mice
Organoid culture was used to assess the stemness and self-renewal capacity of alveolar epithelial type production as well as proinflammatory factor transcription in macrophages and decreased apoptosis in epithelial
- GPR176 promotes fibroblast-to-myofibroblast transition in organ fibrosis progression
Furthermore, fibroblasts abundantly expressed Gpr176 compared to alveolar epithelial cells, endothelial
- NPFF stimulates human ovarian cancer cell invasion by upregulating MMP-9 via ERK1/2 signaling
Epithelial ovarian cancer (EOC) is a leading cause of death among gynecological malignancies.
- Stretch regulates alveologenesis and homeostasis via mesenchymal Gαq/11-mediated TGFβ2 activation
protein α subunits Gαq and Gα11 (Gαq/11) transmit mechanical and chemical signals to activate TGFβ in epithelial
- Identification of a G-protein coupled receptor-related gene signature through bioinformatics analysis to construct a risk model for ovarian cancer prognosis
protein-coupled receptor , Immune infiltration , Molecular marker , Ovarian cancer , Prognostic model , epithelial
- A disturbed metabolite-GPCR axis is associated with microbial dysbiosis in IBD patients: Potential role of GPR109A in macrophages
The role of GPR109A was studied in depth and increased expression of this receptor was detected in epithelial
- G protein-coupled receptors: A target for microbial metabolites and a mechanistic link to microbiome-immune-brain interactions
molecular interactions with specific human cell receptors, particularly expressed on human intestinal epithelial
- Lactate receptor GPR81 drives breast cancer growth and invasiveness through regulation of ECM properties and Notch ligand DLL4
Key findings were additionally studied in other breast cancer cell lines and in mammary epithelial cells
- Activation of PI3K/Akt pathway by G protein-coupled receptor 37 promotes resistance to cisplatin-induced apoptosis in non-small cell lung cancer
tumor formation and growth. (3) GPR37 activates PI3K/Akt/mTOR signal transduction pathways to mediate epithelial-mesenchymal
- Ep 146 with Dr Michael Feigin
He also discussed his experiments and discoveries about GPR161 in mammary epithelial cells, the effect
- SSTR2 positively associates with EGFR and predicts poor prognosis in nasopharyngeal carcinoma
evaluated by immunohistochemistry (IHC) in 491 cases of NPC and 50 cases of non-cancerous nasopharyngeal epithelium SSTR2 and EGFR was significantly increased in NPC patients compared with non-cancerous nasopharyngeal epithelium
- Ep 126 with Dr. Françoise Bachelerie
innate control of the life cycle of papillomavirus, which are commensal inhabiting the healthy human epithelium
