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13 items found for "fibrous dysplasia (FD)"

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Role of G Protein-Coupled Receptors in Hepatic Stellate Cells and Approaches to Anti-Fibrotic ...
Role of G Protein-Coupled Receptors in Hepatic Stellate Cells and Approaches to Anti-Fibrotic Treatment
The complicated lives of GPCRs in cardiac fibroblasts
We also review the hierarchy of signaling events driving the fibrotic response and the communications
GPR84 signaling promotes intestinal mucosal inflammation via enhancing NLRP3 inflammasome activation
lipopolysaccharide (LPS) and TNFα suggests that it may play a role in the development of inflammatory and fibrotic

Wnt pathway inhibition with the porcupine inhibitor LGK974 decreases trabecular bone but not fibrosis in a murine model with fibrotic bone
Fibrous dysplasia (FD) of the bone is characterized by fibrotic, expansile bone lesions caused by activating There are no effective therapies for FD. components of the downstream signaling pathway could serve as a promising therapeutic strategy for FD The Wnt signaling pathway has been implicated in the pathogenesis of FD-like bone, but the specific Wnts bone disease , fibrous dysplasia (FD) , osteoblasts , trabecular bone , G-protein coupled receptor signaling
GPCRs and fibroblast heterogeneity in fibroblast-associated diseases
Sadikot , Apar K Ganti , Surinder K Batra , Maneesh Jain Tags GPCR signaling , fibroblast behavior , fibrotic
GPR176 promotes fibroblast-to-myofibroblast transition in organ fibrosis progression
abundantly expressed Gpr176 compared to alveolar epithelial cells, endothelial cells, and macrophages in the fibrotic