October 2022 Increased Anxiety-like Behaviors in Adgra1-/- Male But Not Female Mice are Attributable To this end, we comprehensively analyzed the potential role of ADGRA1 in the neurobehaviors of mice by We found that Adgra1-/- male but not female mice exhibited elevated anxiety levels in the open field, and spine density as evidenced by elevated expression levels of SYN and PSD95 in amygdalae of male mice activated when compared to wt male mice.

The resulting homozygous hPTH1R-KI (humanized) mice were healthy over at least 10 generations and showed The initial evaluation of these mice and their potential utility for predicting behavior of PTH analogues

September 2022 Angiotensin-(1-7) improves cognitive function and reduces inflammation in mice following

Administration , VIP , Vasoactive intestinal peptide , Voltage-gated sodium channel , gamma chain , mAb , mIgE

Mike then joined the lab of Dr. Muthuswamy moved to the University of Toronto, Mike joined the laboratory of Dr. Mike's Research on Cell Polarity and GPCRs in Cancer Mike shared his research on cell polarity and its Career Trajectory and Faculty Position Yamina and Mike discussed Mike's career trajectory and his decision Towards the end, Yamina asked about job opportunities in Mike's lab, to which Mike responded that potential

Gpr141 -/- mice, which we independently generated, displayed almost no abnormalities in myeloid cell Gpr141 -/- mice showed increased CD11b + Gr1+ neutrophils, CD11b + Gr1- monocytes, CD11c+ dendritic cells the experimental autoimmune encephalomyelitis-induced spinal cord compared with littermate control mice high amounts of interferon-γ, interleukin-17A, and interleukin-6 compared with those from wild-type mice Moreover, CD11c+ dendritic cells (DCs) purified from Gpr141 -/- mice increased cytokine production of