Search Results
29 items found for "malignancy"
- GPR4 in the pH-dependent migration of melanoma cells in the tumor microenvironment
tumor microenvironment Published date December 23, 2022 Abstract Due to its high metastatic potential, malignant proton-sensitive GPCR (pH-GPCR) GPR4, are considered as potential initiators of the signaling cascades relevant to malignant , Frank Haubner , Joachim Wegener , Stephan Schreml Tags Boyden chamber , ECIS , GPR4 , impedance , malignant
- GPCR signaling contributes to immune characteristics of microenvironment and process of EBV-induced lymphomagenesis
Enhanced expression of chemokine receptor-1 (CCR1) on malignant and immunosuppressive cells modulated Collectively, our study identified a previously unknown GPCR-mediated malignant progression and translated
- Comparative Analysis of the GNAI Family Genes in Glioblastoma through Transcriptomics and Single-Cell Technologies
demonstrated that GNAI family genes, specifically GNAI3, were significantly associated with carcinogenesis and malignancy Bianca Tobias William , Chih-Yang Wang Tags G-protein-coupled receptor (GPCR) , genome , glioblastoma , malignancy
- G Proteins and GPCRs in Cancer: Novel Precision Targeted and Immunotherapies
research team has pioneered the study of G proteins and G protein coupled receptors (GPCRs) in human malignancies
- Noval insights and therapeutic strategies for tumor-induced kidney pathologies
fruit flies, as a potential therapeutic target for alleviating renal tubular dysfunction in mice with malignant
- GPR37 promotes colorectal cancer against ferroptosis by reprogramming lipid metabolism via p38-SCD1 axis
via p38-SCD1 axis Published date September 21, 2024 Abstract "Colorectal cancer (CRC) is a prevalent malignant
- GPCRs and fibroblast heterogeneity in fibroblast-associated diseases
personalized medicine approaches to achieve better therapeutic outcomes for fibrosis and fibrosis associated malignancies
- A virally encoded GPCR drives glioblastoma through feed-forward activation of the SK1-S1P1 signaling axis
Here, we showed that US28 increased the malignancy of U251 glioblastoma cells by enhancing signaling
- Structural Basis for the Recognition of GPRC5D by Talquetamab, a Bispecific Antibody for Multiple Myeloma
Multiple Myeloma Published date August 22, 2024 Abstract "Multiple myeloma (MM) is a complex hematological malignancy
- NPFF stimulates human ovarian cancer cell invasion by upregulating MMP-9 via ERK1/2 signaling
Epithelial ovarian cancer (EOC) is a leading cause of death among gynecological malignancies.
- Minireview: functional roles of tissue kallikrein, kinins, and kallikrein-related peptidases in lung cancer
fact, KLK3 is the specific prostate antigen, the only tissue-specific biomarker used to diagnose this malignancy
- Deciphering a GPCR-lncRNA-miRNA Nexus: Identification of an Aberrant Therapeutic Target in Ovarian Cancer
date April 18, 2024 Abstract "Ovarian cancer ranks as a leading cause of mortality among gynecological malignancies
- Identification of a G-protein coupled receptor-related gene signature through bioinformatics analysis to construct a risk model for ovarian cancer prognosis
cancer prognosis Published date June 18, 2024 Abstract " Background: Ovarian cancer (OV) is a common malignant
- Session VI | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Dimitris Placantonakis Abstract "Glioblastoma (GBM) is the most common and aggressive primary brain malignancy His laboratory studies oncogenesis in glioblastoma, the most common brain malignancy, and chromatin organization
- Activation of PI3K/Akt pathway by G protein-coupled receptor 37 promotes resistance to cisplatin-induced apoptosis in non-small cell lung cancer
GPCR gene expression and dysregulation of signal transduction have been recognized as the markers of malignancy
- Expression pattern and clinical significance of beta 2-adrenergic receptor in oral squamous cell carcinoma: an emerging prognostic indicator and future therapeutic target
Abstract Purpose: Beta 2-Adrenergic Receptor (β2-AR) is significantly overexpressed in various types of malignancies
- GPR37 expression as a prognostic marker in gliomas: a bioinformatics-based analysis
that is implicated in different physiological pathways in the brain, and has been linked to various malignancies
- GPR68-ATF4 signaling is a novel prosurvival pathway in glioblastoma activated by acidic extracellular microenvironment
Importantly, OGM was not-acutely toxic to zebrafish and its inhibitory effects were found to spare non-malignant
- Session III | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
professor working on the role of TNF receptors in immunological memory, inflammation and hematological malignancies
- Ep 146 with Dr Michael Feigin
at CSHL where he participated in the development of an organoid system for the culture of normal and malignant
- Ep 124 with Gáspár Pándy-Szekeres
pipeline for GPCRs and since have branched out to multiple areas of GPCR research such as sequence alignments
- Ep 123 with Dr. Lukas Grätz
pipeline for GPCRs and since have branched out to multiple areas of GPCR research such as sequence alignments
- Comparison of infectious complications with BCMA-directed therapies in multiple myeloma
Michael Scordo, Gunjan L Shah, Hani Hassoun, Kylee Maclachlan, Neha Korde, Urvi A Shah, Carlyn Rose Tan, Malin
- Sponsorship Prospectus for Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Align your brand with scientific excellence and innovation.
- Ep 153 with Dr Jacek Mokrosiński
They emphasized the importance of finding a job that aligns with one's interests and strengths and being
- Ep 152 with Dr Arthur Christopoulos
proposed compiling a book on GPCR history through collaborative interviews, considering a symposium to align
- Ep 154 with Dr Badr Sokrat
strategy for finding a suitable postdoc lab, which involved reaching out to labs whose recent research aligned
- Ep 145 with Dr John Janetzko
explained the collaborative culture in Brian's lab, where individuals are encouraged to pursue projects aligned