Search Results

orphan G protein-coupled receptors in pain GPCRs in Oncology and Immunology Deciphering a GPCR-lncRNA-miRNA

We detected the mRNA and protein expression of the melatonin MT2 but not the MT1 receptor in native human reversed by the Gαi protein inhibitor pertussis toxin or knockdown of the MT2 receptor by its specific siRNA

published in Scientific Data by Arne Hansen et a l has introduced a sensitive method for detecting GPCR mRNAs The study reports that human white blood cells express an average of 160 GPCR mRNAs, ranging from 123 to 206, while platelets exhibit a distinct profile with 69 GPCR mRNAs. analysis with previous studies, notably the work by Groot-Kormelink et al., which reported 165 GPCR mRNAs

< GPCR News < GPCRs in Oncology and Immunology Deciphering a GPCR-lncRNA-miRNA Nexus: Identification In this study, we elucidate the tripartite interaction between LPA-signaling, UCA1, and let-7 miRNAs Mechanistically, UCA1 sequesters let-7 miRNAs, effectively neutralizing their tumor-suppressive functions More significantly, intratumoral delivery of UCA1-specific siRNAs inhibits the growth of cisplatin-refractory Isidoro , Yong Sang Song , Danny N Dhanasekaran Tags GPCR , High Grade Serous Ovarian Carcinoma , Let-7 miRNAs

the TGFβ and IFNγ dataset revealed association of genes with different biological processes such as miRNA-mediated

Zhang , Jiayan Fan , Hongyan Gao , Xinyu Xia , Wei Wu , Yuyuan Shi Tags GPCR , GRK6 , OSCC , PKC , miRNA