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September 2022 PLC-IP3-ORAI pathway participates in the activation of the MRGPRB2 receptor in mouse peritoneal

Additionally, we detect a shortening of PC in PINK1-deficient human cellular and mouse models of familial

The mouse cytomegalovirus G protein-coupled receptor homolog, M33, coordinates key features of in vivo The mouse cytomegalovirus (MCMV) GPCR, M33, facilitates dendritic cell (DC)-dependent viremia, the extravasation The mouse CMV (MCMV) GPCR homolog, designated M33, is important for cell-associated virus spread and

Here we used zebrafish and mouse models to probe the role of BLT2 in macrophage function during inflammation We detected BLT2 expression in bone marrow derived and peritoneal macrophages of mouse models. Raghavendra G Mirmira Tags G-protein coupled receptor (GPCR) , Macrophage , inflammation , metabolism , mouse

Oncology and Immunology The GPCR adaptor protein Norbin controls the trafficking of C5aR1 and CXCR4 in mouse Norbin suppresses C5aR1 signalling in mouse neutrophils by limiting the C5a-stimulated membrane translocation

Methods: We studied human and mouse PMN signaling elicited by mtDAMPs (GPCR surface expression; protein Predicted rescue therapies were assessed in cell systems and mouse injury-dependent pneumonia models. Either GRK2 or HDAC inhibition prevented loss of mouse lung bacterial clearance, but only the combination