Danger-signaling molecular patterns such as the N-formylated peptides that are formed during bacterial and mitochondrial protein synthesis and recognized by formyl peptide receptors (FPRs) and free fatty acids recognized by free fatty acid receptors (FFARs) regulate neutrophil functions. Martina Sundqvist, Lena Björkman, Jonas Mårtensson Tags GPCR , allosteric modulation , biased signaling , pattern recognition , receptor transactivation Source Contribute to the GPCR News Coming soon Become a Contributor

< GPCR News < GPCRs in Oncology and Immunology Structural Basis for the Recognition of GPRC5D by Talquetamab complexed with the Fab fragment of talquetamab, using cryo-electron microscopy, providing the basis for recognition

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ML/AI can be powerful for identifying abstract patterns within large data where traditional methods would

We have decoded the mechanisms underlying recognition of fish oil (unsaturated fatty acids) and other lipids by GPCRs (Science 2023, Science Advance 2021, PNAS 2023, Nature Metabolism 2023), recognition

He is currently the Senior Investigator and Chief of the Molecular Recognition Section, Laboratory of

The winning logo designer will receive well-deserved recognition and a cash prize of $250.

Understanding the dynamics of GPCR signaling in fibroblasts with disease progression can help in the recognition

However, it was unclear how chemokine ligands, activators and antagonists recognize hCCR3, and quantitative This study constructed a nanogold receptor sensor using hCCR3 as the molecular recognition element and

Retreat Program < Back to schedule A positive Allosteric Modulator of M1 Acetylcholine Receptors Improves Cognitive

Hence, Remo is proteolytically processed, either by the GAIN domain or an alternative protease that cleaved Collectively these proteins form a cell surface complex that acts as a recognition platform for Wnt ligands

in Oncology and Immunology A GPCR-neuropeptide axis dampens hyperactive neutrophils by promoting an alternative-like counter-regulated interferon (IFN) γ-mediated neutrophil polarization during acute lung infection by favoring an alternative-like

protein) within patient luminal carcinoma samples exhibiting non-invasive or invasive features, the latter and synaptogenesis during development, and the absence of the ligand-induced signaling causes object recognition