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Axon regeneration in response to injury is determined by the interaction between the extracellular environment In this study, we investigated the role of chemical signaling in axon regeneration in Caenorhabditis However, it remains unclear what signals activate the EGL-30 pathway in axon regeneration. Consistent with this, we found that ascr#5 activates the axon regeneration pathway via SRG-36/SRG-37 Thus, ascaroside signaling promotes axon regeneration by activating the GPCR-Gqα pathway.

2022 GPR3 expression in retinal ganglion cells contributes to neuron survival and accelerates axonal regeneration However, the potential role of GPR3 in axonal regeneration after neuronal injury has not been elucidated Herein, we investigated retinal GPR3 expression and its possible involvement in axonal regeneration after Evaluation of the effect of GPR3 on axonal regeneration using GPR3 knockout mice revealed that GPR3 in RGCs participates in axonal regeneration after optic nerve crush (ONC) under zymosan stimulation.

systems, where it regulates various processes including neuroendocrine release, cognition, and nerve regeneration

Session VI AGPCRs shaping the nervous system ADGRCs in glutamatergic synapse formation, maintenance and degeneration dopaminergic neurotransmission Nicole Perry-Hauser ADGRCs in glutamatergic synapse formation, maintenance and degeneration

Vanhollebeke Benoit2, Langenhan Tobias1 1Rudolf Schönheimer Institute of Biochemistry, Division of General research scientist at Columbia University, New York, where I studied the mechanisms of motor neuron degeneration Langenhan where I am studying and characterizing newly generated adhesion GPCR receptors in Drosophila